Gene name: SOP4
Reference locus (S288C): YJL192C
Gene biotype: protein_coding
Description: ER-membrane protein; subunit of evolutionarily conserved EMC (Endoplasmic Reticulum Membrane Complex) implicated in ERAD (ER-associated degradation) and proper assembly of multi-pass transmembrane (TM) proteins; EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein Tom5 of TOM (Translocase of the Mitochondrial Outer Membrane) complex; suppressor of pma1-7, deletion of SOP4 slows down export of wild-type Pma1p and Pma1-7 from the ER
Top 10 interactors (score): EMC10 (0.994); EMC3 (0.983); EMC6 (0.979); EMC2 (0.968); EMC4 (0.967); EMC5 (0.965); EMC1 (0.961); YOR1 (0.756); YET2 (0.698); ILM1 (0.666); SSH1 (0.621); EMP65 (0.617); APM1 (0.613); PMA1 (0.592); YIP4 (0.59); GSF2 (0.573); ARE1 (0.573); PER33 (0.572); ERG9 (0.568); GTO3 (0.53)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:61109-61813:- | gene-YJL192C_AKU4011 | rna-NM_001181625.1_AKU4011 | cds-NP_012343.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000181.1:38390-39094:- | gene-YJL192C_BG1 | rna-NM_001181625.1_BG1 | cds-NP_012343.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:72928-73632:- | gene-YJL192C_Bruggeman | rna-NM_001181625.1_Bruggeman | cds-NP_012343.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:76132-76836:- | gene-YJL192C_CAT1 | rna-NM_001181625.1_CAT1 | cds-NP_012343.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:66744-67448:- | gene-YJL192C_CBS1585 | rna-NM_001181625.1_CBS1585 | cds-NP_012343.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:91492-92196:- | gene-YJL192C_CBS436 | rna-NM_001181625.1_CBS436 | cds-NP_012343.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:63226-63930:- | gene-YJL192C_CBS6412 | rna-NM_001181625.1_CBS6412 | cds-NP_012343.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:64219-64923:- | gene-YJL192C_CBS6413 | rna-NM_001181625.1_CBS6413 | cds-NP_012343.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:55175-55879:- | gene-YJL192C_CENPK1137D | rna-NM_001181625.1_CENPK1137D | cds-NP_012343.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:65408-66112:- | gene-YJL192C_EthanolRed | rna-NM_001181625.1_EthanolRed | cds-NP_012343.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:70688-71392:- | gene-YJL192C_FaliES1 | rna-NM_001181625.1_FaliES1 | cds-NP_012343.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000164.1:47359-48063:+ | gene-YJL192C_JAY291 | rna-NM_001181625.1_JAY291 | cds-NP_012343.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:74656-75360:- | gene-YJL192C_MUCL30387 | rna-NM_001181625.1_MUCL30387 | cds-NP_012343.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:70817-71521:- | gene-YJL192C_MUCL30388 | rna-NM_001181625.1_MUCL30388 | cds-NP_012343.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:65486-66190:- | gene-YJL192C_MUCL39482 | rna-NM_001181625.1_MUCL39482 | cds-NP_012343.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:70088-70792:- | gene-YJL192C_MUCL42920 | rna-NM_001181625.1_MUCL42920 | cds-NP_012343.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:72689-73393:- | gene-YJL192C_NCIM3186 | rna-NM_001181625.1_NCIM3186 | cds-NP_012343.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:64096-64800:- | gene-YJL192C_NCYC1407 | rna-NM_001181625.1_NCYC1407 | cds-NP_012343.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:76790-77494:- | gene-YJL192C_PE2H3 | rna-NM_001181625.1_PE2H3 | cds-NP_012343.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:76429-77133:- | gene-YJL192C_PE2H4 | rna-NM_001181625.1_PE2H4 | cds-NP_012343.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:72710-73414:- | gene-YJL192C_S288C | rna-NM_001181625.1_S288C | cds-NP_012343.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000022.1:80468-81172:+ | gene-YJL192C_SA1 | rna-NM_001181625.1_SA1 | cds-NP_012343.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:63880-64584:- | gene-YJL192C_ThermosaccDry | rna-NM_001181625.1_ThermosaccDry | cds-NP_012343.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:70750-71454:- | gene-YJL192C_VR1 | rna-NM_001181625.1_VR1 | cds-NP_012343.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:51464-52168:- | gene-YJL192C_ZTW1 | rna-NM_001181625.1_ZTW1 | cds-NP_012343.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:75792-76496:- | gene-YJL192C_Sparadoxus | rna-NM_001181625.1_Sparadoxus | cds-NP_012343.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |