SOK2 (YMR016C)


Gene profile

Gene name: SOK2
Reference locus (S288C): YMR016C
Gene biotype: protein_coding

Description: Nuclear protein that negatively regulates pseudohyphal differentiation; plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; relocalizes to the cytosol in response to hypoxia; SOK2 has a paralog, PHD1, that arose from the whole genome duplication

Top 10 interactors (score): TPK2 (0.94); TPK1 (0.914); TPK3 (0.911); TEC1 (0.907); MSN2 (0.883); YAP6 (0.857); NRG1 (0.831); SKO1 (0.819); STE12 (0.806); FLO11 (0.787); CIN5 (0.787); ROX1 (0.781); YAK1 (0.772); EFG1 (0.757); RIM101 (0.748); SWI4 (0.746); TUP1 (0.732); UME6 (0.73); ASH1 (0.722); SKN7 (0.716)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:352860-355190:- gene-YMR016C_AKU4011 rna-NM_001182512.1_AKU4011 cds-NP_013729.1_AKU4011 98.1 98.8 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:187657-190011:+ gene-YMR016C_BG1 rna-NM_001182512.1_BG1 cds-NP_013729.1_BG1 99.6 99.8 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:292803-295133:- gene-YMR016C_Bruggeman rna-NM_001182512.1_Bruggeman cds-NP_013729.1_Bruggeman 98.5 98.8 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:295296-297653:- gene-YMR016C_CAT1 rna-NM_001182512.1_CAT1 cds-NP_013729.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:285801-288131:- gene-YMR016C_CBS1585 rna-NM_001182512.1_CBS1585 cds-NP_013729.1_CBS1585 98.1 98.8 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:291324-293681:- gene-YMR016C_CBS436 rna-NM_001182512.1_CBS436 cds-NP_013729.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:399205-401535:- gene-YMR016C_CBS6412 rna-NM_001182512.1_CBS6412 cds-NP_013729.1_CBS6412 98.1 98.8 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:285057-287387:- gene-YMR016C_CBS6413 rna-NM_001182512.1_CBS6413 cds-NP_013729.1_CBS6413 98.1 98.8 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:297967-300324:- gene-YMR016C_CENPK1137D rna-NM_001182512.1_CENPK1137D cds-NP_013729.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:285608-287962:- gene-YMR016C_EthanolRed rna-NM_001182512.1_EthanolRed cds-NP_013729.1_EthanolRed 99.1 99.8 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:288791-291145:- gene-YMR016C_FaliES1 rna-NM_001182512.1_FaliES1 cds-NP_013729.1_FaliES1 99.2 99.8 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:145788-148142:+ gene-YMR016C_JAY291 rna-NM_001182512.1_JAY291 cds-NP_013729.1_JAY291 99.6 99.8 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:290514-292844:- gene-YMR016C_MUCL30387 rna-NM_001182512.1_MUCL30387 cds-NP_013729.1_MUCL30387 98.6 98.8 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:295188-297518:- gene-YMR016C_MUCL30388 rna-NM_001182512.1_MUCL30388 cds-NP_013729.1_MUCL30388 98.2 98.8 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:286086-288416:- gene-YMR016C_MUCL39482 rna-NM_001182512.1_MUCL39482 cds-NP_013729.1_MUCL39482 98.1 98.8 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:291871-294225:- gene-YMR016C_MUCL42920 rna-NM_001182512.1_MUCL42920 cds-NP_013729.1_MUCL42920 99.6 99.8 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:303190-305547:- gene-YMR016C_NCIM3186 rna-NM_001182512.1_NCIM3186 cds-NP_013729.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:286003-288333:- gene-YMR016C_NCYC1407 rna-NM_001182512.1_NCYC1407 cds-NP_013729.1_NCYC1407 98.1 98.8 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:291930-294284:- gene-YMR016C_PE2H3 rna-NM_001182512.1_PE2H3 cds-NP_013729.1_PE2H3 99.6 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:298025-300379:- gene-YMR016C_PE2H4 rna-NM_001182512.1_PE2H4 cds-NP_013729.1_PE2H4 99.6 99.8 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:303236-305593:- gene-YMR016C_S288C rna-NM_001182512.1_S288C cds-NP_013729.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:232673-235030:+ gene-YMR016C_SA1 rna-NM_001182512.1_SA1 cds-NP_013729.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:285860-288214:- gene-YMR016C_ThermosaccDry rna-NM_001182512.1_ThermosaccDry cds-NP_013729.1_ThermosaccDry 99.3 99.8 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:289814-292171:- gene-YMR016C_VR1 rna-NM_001182512.1_VR1 cds-NP_013729.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:264907-267237:- gene-YMR016C_ZTW1 rna-NM_001182512.1_ZTW1 cds-NP_013729.1_ZTW1 98.2 98.8 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:298752-301106:- gene-YMR016C_Sparadoxus rna-NM_001182512.1_Sparadoxus cds-NP_013729.1_Sparadoxus 87.0 99.5 Verified 1 1 1 False True False False False

Additional files