SOK1 (YDR006C)


Gene profile

Gene name: SOK1
Reference locus (S288C): YDR006C
Gene biotype: protein_coding

Description: Protein of unknown function; overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13

Top 10 interactors (score): UBR1 (0.85); CUP9 (0.817); EFG1 (0.694); MBR1 (0.682); TAF11 (0.681); TPK1 (0.681); FIG4 (0.647); TPK2 (0.62); TPK3 (0.592); NRG1 (0.581); CYR1 (0.58); SOK2 (0.561); RAS1 (0.526); TMA19 (0.489); RIM1 (0.481); ZAP1 (0.481); RPN11 (0.474); YNR021W (0.473); ENT2 (0.465); ENT1 (0.465)

Homologues (species, bitscore): TCP11L2 (Homo sapiens, 74.3); Tcp11x2 (Mus musculus, 79.0); tcp11l1 (Danio rerio, 70.1); tcp11l2 (Xenopus tropicalis, 77.0); CG16721 (Drosophila melanogaster, 65.1); M05D6.2 (Caenorhabditis elegans, 54.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:443793-446498:- gene-YDR006C_AKU4011 rna-NM_001180314.3_AKU4011 cds-NP_010289.3_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:102653-105358:+ gene-YDR006C_BG1 rna-NM_001180314.3_BG1 cds-NP_010289.3_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:464399-467104:- gene-YDR006C_Bruggeman rna-NM_001180314.3_Bruggeman cds-NP_010289.3_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:457244-459949:- gene-YDR006C_CAT1 rna-NM_001180314.3_CAT1 cds-NP_010289.3_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:441005-443710:- gene-YDR006C_CBS1585 rna-NM_001180314.3_CBS1585 cds-NP_010289.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:457774-460479:- gene-YDR006C_CBS436 rna-NM_001180314.3_CBS436 cds-NP_010289.3_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:438252-440957:- gene-YDR006C_CBS6412 rna-NM_001180314.3_CBS6412 cds-NP_010289.3_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:459943-462648:- gene-YDR006C_CBS6413 rna-NM_001180314.3_CBS6413 cds-NP_010289.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:457405-460110:- gene-YDR006C_CENPK1137D rna-NM_001180314.3_CENPK1137D cds-NP_010289.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:452624-455329:- gene-YDR006C_EthanolRed rna-NM_001180314.3_EthanolRed cds-NP_010289.3_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:458795-461500:- gene-YDR006C_FaliES1 rna-NM_001180314.3_FaliES1 cds-NP_010289.3_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000442.1:10559-13264:+ gene-YDR006C_JAY291 rna-NM_001180314.3_JAY291 cds-NP_010289.3_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:458272-460977:- gene-YDR006C_MUCL30387 rna-NM_001180314.3_MUCL30387 cds-NP_010289.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:448732-451437:- gene-YDR006C_MUCL30388 rna-NM_001180314.3_MUCL30388 cds-NP_010289.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:442374-445079:- gene-YDR006C_MUCL39482 rna-NM_001180314.3_MUCL39482 cds-NP_010289.3_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:363805-366510:- gene-YDR006C_MUCL42920 rna-NM_001180314.3_MUCL42920 cds-NP_010289.3_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:458465-461170:- gene-YDR006C_NCIM3186 rna-NM_001180314.3_NCIM3186 cds-NP_010289.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:441296-444001:- gene-YDR006C_NCYC1407 rna-NM_001180314.3_NCYC1407 cds-NP_010289.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:456911-459616:- gene-YDR006C_PE2H3 rna-NM_001180314.3_PE2H3 cds-NP_010289.3_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:456216-458921:- gene-YDR006C_PE2H4 rna-NM_001180314.3_PE2H4 cds-NP_010289.3_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:458542-461247:- gene-YDR006C_S288C rna-NM_001180314.3_S288C cds-NP_010289.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000099.1:10720-13425:+ gene-YDR006C_SA1 rna-NM_001180314.3_SA1 cds-NP_010289.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:458274-460979:- gene-YDR006C_ThermosaccDry rna-NM_001180314.3_ThermosaccDry cds-NP_010289.3_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:462714-465419:- gene-YDR006C_VR1 rna-NM_001180314.3_VR1 cds-NP_010289.3_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:456170-458875:- gene-YDR006C_ZTW1 rna-NM_001180314.3_ZTW1 cds-NP_010289.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:460526-463231:- gene-YDR006C_Sparadoxus rna-NM_001180314.3_Sparadoxus cds-NP_010289.3_Sparadoxus 92.4 99.9 Verified 1 1 1 False True False False False

Additional files