Gene name: SOD1
Reference locus (S288C): YJR104C
Gene biotype: protein_coding
Description: Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS complements a null allele; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex; Belongs to the Cu-Zn superoxide dismutase family
Top 10 interactors (score): SOD2 (0.999); CCS1 (0.999); CTT1 (0.998); CTA1 (0.997); YNK1 (0.987); CDC42 (0.982); MRP1 (0.981); RSM26 (0.981); TPI1 (0.98); COX17 (0.977); TSA1 (0.969); ATX1 (0.954); MIA40 (0.945); GLR1 (0.93); TRX2 (0.929); ACO1 (0.922); AHP1 (0.916); KRS1 (0.915); GPX2 (0.913); GSH1 (0.909)
Homologues (species, bitscore): SOD1 (Homo sapiens, 167.9); Sod1 (Mus musculus, 173.3); sod1 (Danio rerio, 184.1); sod1 (Xenopus tropicalis, 174.9); Sod (Drosophila melanogaster, 146.4); sod-1 (Caenorhabditis elegans, 177.6); CSD2 (Arabidopsis thaliana, 173.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:594054-594518:- | gene-YJR104C_AKU4011 | rna-NM_001181762.1_AKU4011 | cds-NP_012638.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:13076-13540:+ | gene-YJR104C_BG1 | rna-NM_001181762.1_BG1 | cds-NP_012638.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:609782-610246:- | gene-YJR104C_Bruggeman | rna-NM_001181762.1_Bruggeman | cds-NP_012638.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:613262-613726:- | gene-YJR104C_CAT1 | rna-NM_001181762.1_CAT1 | cds-NP_012638.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:606110-606574:- | gene-YJR104C_CBS1585 | rna-NM_001181762.1_CBS1585 | cds-NP_012638.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:624701-625165:- | gene-YJR104C_CBS436 | rna-NM_001181762.1_CBS436 | cds-NP_012638.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:593257-593721:- | gene-YJR104C_CBS6412 | rna-NM_001181762.1_CBS6412 | cds-NP_012638.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:595518-595982:- | gene-YJR104C_CBS6413 | rna-NM_001181762.1_CBS6413 | cds-NP_012638.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:604868-605332:- | gene-YJR104C_CENPK1137D | rna-NM_001181762.1_CENPK1137D | cds-NP_012638.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:598472-598936:- | gene-YJR104C_EthanolRed | rna-NM_001181762.1_EthanolRed | cds-NP_012638.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:609938-610402:- | gene-YJR104C_FaliES1 | rna-NM_001181762.1_FaliES1 | cds-NP_012638.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:79019-79483:+ | gene-YJR104C_JAY291 | rna-NM_001181762.1_JAY291 | cds-NP_012638.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:608331-608795:- | gene-YJR104C_MUCL30387 | rna-NM_001181762.1_MUCL30387 | cds-NP_012638.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:606301-606765:- | gene-YJR104C_MUCL30388 | rna-NM_001181762.1_MUCL30388 | cds-NP_012638.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:599578-600042:- | gene-YJR104C_MUCL39482 | rna-NM_001181762.1_MUCL39482 | cds-NP_012638.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:603829-604293:- | gene-YJR104C_MUCL42920 | rna-NM_001181762.1_MUCL42920 | cds-NP_012638.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:622529-622993:- | gene-YJR104C_NCIM3186 | rna-NM_001181762.1_NCIM3186 | cds-NP_012638.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:597136-597600:- | gene-YJR104C_NCYC1407 | rna-NM_001181762.1_NCYC1407 | cds-NP_012638.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:615033-615497:- | gene-YJR104C_PE2H3 | rna-NM_001181762.1_PE2H3 | cds-NP_012638.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:608722-609186:- | gene-YJR104C_PE2H4 | rna-NM_001181762.1_PE2H4 | cds-NP_012638.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:622550-623014:- | gene-YJR104C_S288C | rna-NM_001181762.1_S288C | cds-NP_012638.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:81107-81571:- | gene-YJR104C_SA1 | rna-NM_001181762.1_SA1 | cds-NP_012638.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:603872-604336:- | gene-YJR104C_ThermosaccDry | rna-NM_001181762.1_ThermosaccDry | cds-NP_012638.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:605977-606441:- | gene-YJR104C_VR1 | rna-NM_001181762.1_VR1 | cds-NP_012638.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:583237-583701:- | gene-YJR104C_ZTW1 | rna-NM_001181762.1_ZTW1 | cds-NP_012638.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:617081-617545:- | gene-YJR104C_Sparadoxus | rna-NM_001181762.1_Sparadoxus | cds-NP_012638.1_Sparadoxus | 94.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |