SNT2 (YGL131C)


Gene profile

Gene name: SNT2
Reference locus (S288C): YGL131C
Gene biotype: protein_coding

Description: Subunit of Snt2C complex, RING finger ubiquitin ligase (E3); physically associates with Ecm5p and Rpd3p; along with Ecm5p, recruits Rpd3p to small number of promoters; colocalizes with Ecm5p, independently of Rpd3p, to promoters of stress response genes upon oxidative stress; involved in ubiquitination, degradation of excess histones; interacts with Ubc4p; role in regulating genes encoding amine transporters; relocalizes from nucleus to cytoplasm upon DNA replication stress

Top 10 interactors (score): ECM5 (0.956); RPD3 (0.949); VMA6 (0.896); MET2 (0.896); ATG7 (0.896); EAF6 (0.782); SET1 (0.74); SET3 (0.696); SIF2 (0.692); SPP1 (0.687); FAR11 (0.677); SDC1 (0.662); YDR306C (0.654); SPT6 (0.646); VAM6 (0.626); YLR352W (0.612); SAS3 (0.602); SAS2 (0.602); ESA1 (0.602); MET18 (0.602)

Homologues (species, bitscore): PHF14 (Homo sapiens, 80.5); Phf14 (Mus musculus, 84.7); phf14 (Danio rerio, 82.0); phf14 (Xenopus tropicalis, 79.0); rno (Drosophila melanogaster, 78.6); zfp-1 (Caenorhabditis elegans, 71.6); SDG14 (Arabidopsis thaliana, 76.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:264461-268672:- gene-YGL131C_AKU4011 rna-NM_001180996.1_AKU4011 cds-NP_011384.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:136505-140716:+ gene-YGL131C_BG1 rna-NM_001180996.1_BG1 cds-NP_011384.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:267160-271371:- gene-YGL131C_Bruggeman rna-NM_001180996.1_Bruggeman cds-NP_011384.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:262749-266960:- gene-YGL131C_CAT1 rna-NM_001180996.1_CAT1 cds-NP_011384.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:267788-271999:- gene-YGL131C_CBS1585 rna-NM_001180996.1_CBS1585 cds-NP_011384.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:262701-266912:- gene-YGL131C_CBS436 rna-NM_001180996.1_CBS436 cds-NP_011384.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:253429-257640:- gene-YGL131C_CBS6412 rna-NM_001180996.1_CBS6412 cds-NP_011384.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:262649-266860:- gene-YGL131C_CBS6413 rna-NM_001180996.1_CBS6413 cds-NP_011384.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:261907-266118:- gene-YGL131C_CENPK1137D rna-NM_001180996.1_CENPK1137D cds-NP_011384.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:254173-258384:- gene-YGL131C_EthanolRed rna-NM_001180996.1_EthanolRed cds-NP_011384.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:256129-260340:- gene-YGL131C_FaliES1 rna-NM_001180996.1_FaliES1 cds-NP_011384.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000408.1:8851-13062:+ gene-YGL131C_JAY291 rna-NM_001180996.1_JAY291 cds-NP_011384.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:264130-268341:- gene-YGL131C_MUCL30387 rna-NM_001180996.1_MUCL30387 cds-NP_011384.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:267248-271459:- gene-YGL131C_MUCL30388 rna-NM_001180996.1_MUCL30388 cds-NP_011384.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:264874-269085:- gene-YGL131C_MUCL39482 rna-NM_001180996.1_MUCL39482 cds-NP_011384.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:268122-272333:- gene-YGL131C_MUCL42920 rna-NM_001180996.1_MUCL42920 cds-NP_011384.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:261648-265859:- gene-YGL131C_NCIM3186 rna-NM_001180996.1_NCIM3186 cds-NP_011384.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:256364-260575:- gene-YGL131C_NCYC1407 rna-NM_001180996.1_NCYC1407 cds-NP_011384.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:257754-261965:- gene-YGL131C_PE2H3 rna-NM_001180996.1_PE2H3 cds-NP_011384.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:262752-266963:- gene-YGL131C_PE2H4 rna-NM_001180996.1_PE2H4 cds-NP_011384.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:261648-265859:- gene-YGL131C_S288C rna-NM_001180996.1_S288C cds-NP_011384.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000064.1:6533-10744:- gene-YGL131C_SA1 rna-NM_001180996.1_SA1 cds-NP_011384.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:256358-260569:- gene-YGL131C_ThermosaccDry rna-NM_001180996.1_ThermosaccDry cds-NP_011384.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:366486-370697:- gene-YGL131C_VR1 rna-NM_001180996.1_VR1 cds-NP_011384.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:253937-258148:- gene-YGL131C_ZTW1 rna-NM_001180996.1_ZTW1 cds-NP_011384.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:259963-264174:- gene-YGL131C_Sparadoxus rna-NM_001180996.1_Sparadoxus cds-NP_011384.1_Sparadoxus 85.9 99.8 Verified 1 1 1 False True False False False

Additional files