SND2 (YLR065C)


Gene profile

Gene name: SND2
Reference locus (S288C): YLR065C
Gene biotype: protein_coding

Description: Protein involved in SRP-independent targeting of substrates to the ER; component of an alternative ER targeting pathway that has partial functional redundancy with the GET pathway; preference for substrates with downstream transmembrane domains; interacts with Snd1p, Pho88p/Snd3p, and Sec61p-translocon subunits; can compensate for loss of SRP; role in the late endosome-vacuole interface; putative role in secretory protein quality control; Belongs to the TMEM208 family

Top 10 interactors (score): GET1 (0.955); SND1 (0.944); PHO88 (0.892); PRE4 (0.851); GET3 (0.85); GET2 (0.841); YAR028W (0.817); GET4 (0.816); ENV9 (0.763); MIL1 (0.749); YDR018C (0.748); YBR137W (0.746); MST28 (0.745); SEC61 (0.742); TPO5 (0.72); YSY6 (0.718); ENV11 (0.715); MAM3 (0.715); UIP3 (0.711); SLY41 (0.709)

Homologues (species, bitscore): AT4G30500 (Arabidopsis thaliana, 51.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:248845-249390:- gene-YLR065C_AKU4011 rna-NM_001181952.1_AKU4011 cds-NP_013166.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:211986-212531:- gene-YLR065C_BG1 rna-NM_001181952.1_BG1 cds-NP_013166.1_BG1 98.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:258754-259299:- gene-YLR065C_Bruggeman rna-NM_001181952.1_Bruggeman cds-NP_013166.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:259071-259616:- gene-YLR065C_CAT1 rna-NM_001181952.1_CAT1 cds-NP_013166.1_CAT1 98.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:255961-256506:- gene-YLR065C_CBS1585 rna-NM_001181952.1_CBS1585 cds-NP_013166.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:246583-247128:- gene-YLR065C_CBS436 rna-NM_001181952.1_CBS436 cds-NP_013166.1_CBS436 98.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:254399-254944:- gene-YLR065C_CBS6412 rna-NM_001181952.1_CBS6412 cds-NP_013166.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:256232-256777:- gene-YLR065C_CBS6413 rna-NM_001181952.1_CBS6413 cds-NP_013166.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:251395-251940:- gene-YLR065C_CENPK1137D rna-NM_001181952.1_CENPK1137D cds-NP_013166.1_CENPK1137D 99.2 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:248366-248911:- gene-YLR065C_EthanolRed rna-NM_001181952.1_EthanolRed cds-NP_013166.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:248242-248787:- gene-YLR065C_FaliES1 rna-NM_001181952.1_FaliES1 cds-NP_013166.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000129.1:23177-23722:- gene-YLR065C_JAY291 rna-NM_001181952.1_JAY291 cds-NP_013166.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:256123-256668:- gene-YLR065C_MUCL30387 rna-NM_001181952.1_MUCL30387 cds-NP_013166.1_MUCL30387 98.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:263766-264311:- gene-YLR065C_MUCL30388 rna-NM_001181952.1_MUCL30388 cds-NP_013166.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:256472-257017:- gene-YLR065C_MUCL39482 rna-NM_001181952.1_MUCL39482 cds-NP_013166.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:256393-256938:- gene-YLR065C_MUCL42920 rna-NM_001181952.1_MUCL42920 cds-NP_013166.1_MUCL42920 99.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:266347-266892:- gene-YLR065C_NCIM3186 rna-NM_001181952.1_NCIM3186 cds-NP_013166.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:248547-249092:- gene-YLR065C_NCYC1407 rna-NM_001181952.1_NCYC1407 cds-NP_013166.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:254414-254959:- gene-YLR065C_PE2H3 rna-NM_001181952.1_PE2H3 cds-NP_013166.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:254155-254700:- gene-YLR065C_PE2H4 rna-NM_001181952.1_PE2H4 cds-NP_013166.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:266373-266918:- gene-YLR065C_S288C rna-NM_001181952.1_S288C cds-NP_013166.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000033.1:107272-107817:+ gene-YLR065C_SA1 rna-NM_001181952.1_SA1 cds-NP_013166.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:248418-248963:- gene-YLR065C_ThermosaccDry rna-NM_001181952.1_ThermosaccDry cds-NP_013166.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:262107-262652:- gene-YLR065C_VR1 rna-NM_001181952.1_VR1 cds-NP_013166.1_VR1 98.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:247805-248350:- gene-YLR065C_ZTW1 rna-NM_001181952.1_ZTW1 cds-NP_013166.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:256685-257230:- gene-YLR065C_Sparadoxus rna-NM_001181952.1_Sparadoxus cds-NP_013166.1_Sparadoxus 89.9 100.0 Verified 1 1 1 False True False False False

Additional files