Gene name: SMY2
Reference locus (S288C): YBR172C
Gene biotype: protein_coding
Description: GYF domain protein; involved in COPII vesicle formation; interacts with the Sec23p/Sec24p subcomplex; overexpression suppresses the temperature sensitivity of a myo2 mutant; similar to S. pombe Mpd2; SMY2 has a paralog, SYH1, that arose from the whole genome duplication; Belongs to the SMY2/mpd2 family
Top 10 interactors (score): MSL5 (0.97); EAP1 (0.958); DHH1 (0.897); MUD2 (0.891); MOT2 (0.89); CDC33 (0.843); PRP39 (0.796); SCP160 (0.746); CLF1 (0.724); CDC39 (0.709); SEC24 (0.708); YOS1 (0.698); YBL012C (0.696); YBR071W (0.696); HEL2 (0.692); YBR144C (0.67); SFB2 (0.654); YBL044W (0.619); ECM15 (0.617); YBL083C (0.613)
Homologues (species, bitscore): GIGYF2 (Homo sapiens, 58.2); Gigyf2 (Mus musculus, 58.2); gigyf1 (Danio rerio, 69.7); gigyf1 (Xenopus tropicalis, 54.7); CG11148 (Drosophila melanogaster, 50.1); C18H9.3 (Caenorhabditis elegans, 52.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:562022-564244:- | gene-YBR172C_AKU4011 | rna-NM_001178520.3_AKU4011 | cds-NP_009731.4_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:552530-554752:- | gene-YBR172C_BG1 | rna-NM_001178520.3_BG1 | cds-NP_009731.4_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:565043-567265:- | gene-YBR172C_Bruggeman | rna-NM_001178520.3_Bruggeman | cds-NP_009731.4_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:459157-461379:- | gene-YBR172C_CAT1 | rna-NM_001178520.3_CAT1 | cds-NP_009731.4_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:553803-556025:- | gene-YBR172C_CBS1585 | rna-NM_001178520.3_CBS1585 | cds-NP_009731.4_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:561883-564105:- | gene-YBR172C_CBS436 | rna-NM_001178520.3_CBS436 | cds-NP_009731.4_CBS436 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:651288-653510:- | gene-YBR172C_CBS6412 | rna-NM_001178520.3_CBS6412 | cds-NP_009731.4_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:559359-561581:- | gene-YBR172C_CBS6413 | rna-NM_001178520.3_CBS6413 | cds-NP_009731.4_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:572947-575169:- | gene-YBR172C_CENPK1137D | rna-NM_001178520.3_CENPK1137D | cds-NP_009731.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:687864-690086:- | gene-YBR172C_EthanolRed | rna-NM_001178520.3_EthanolRed | cds-NP_009731.4_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:578096-580318:- | gene-YBR172C_FaliES1 | rna-NM_001178520.3_FaliES1 | cds-NP_009731.4_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000310.1:17928-20150:- | gene-YBR172C_JAY291 | rna-NM_001178520.3_JAY291 | cds-NP_009731.4_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:566696-568918:- | gene-YBR172C_MUCL30387 | rna-NM_001178520.3_MUCL30387 | cds-NP_009731.4_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:565982-568204:- | gene-YBR172C_MUCL30388 | rna-NM_001178520.3_MUCL30388 | cds-NP_009731.4_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:552176-554398:- | gene-YBR172C_MUCL39482 | rna-NM_001178520.3_MUCL39482 | cds-NP_009731.4_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:562098-564320:- | gene-YBR172C_MUCL42920 | rna-NM_001178520.3_MUCL42920 | cds-NP_009731.4_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:578947-581169:- | gene-YBR172C_NCIM3186 | rna-NM_001178520.3_NCIM3186 | cds-NP_009731.4_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:554745-556967:- | gene-YBR172C_NCYC1407 | rna-NM_001178520.3_NCYC1407 | cds-NP_009731.4_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:567402-569624:- | gene-YBR172C_PE2H3 | rna-NM_001178520.3_PE2H3 | cds-NP_009731.4_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:565078-567300:- | gene-YBR172C_PE2H4 | rna-NM_001178520.3_PE2H4 | cds-NP_009731.4_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:579150-581372:- | gene-YBR172C_S288C | rna-NM_001178520.3_S288C | cds-NP_009731.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000032.1:100394-102616:- | gene-YBR172C_SA1 | rna-NM_001178520.3_SA1 | cds-NP_009731.4_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:577106-579328:- | gene-YBR172C_ThermosaccDry | rna-NM_001178520.3_ThermosaccDry | cds-NP_009731.4_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:558553-560775:- | gene-YBR172C_VR1 | rna-NM_001178520.3_VR1 | cds-NP_009731.4_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:552223-554445:- | gene-YBR172C_ZTW1 | rna-NM_001178520.3_ZTW1 | cds-NP_009731.4_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:589592-591802:- | gene-YBR172C_Sparadoxus | rna-NM_001178520.3_Sparadoxus | cds-NP_009731.4_Sparadoxus | 83.8 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |