SML1 (YML058W)


Gene profile

Gene name: SML1
Reference locus (S288C): YML058W
Gene biotype: protein_coding

Description: Ribonucleotide reductase inhibitor; involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase; SML1 has a paralog, DIF1, that arose from the whole genome duplication

Top 10 interactors (score): RAD53 (0.996); MEC1 (0.993); DUN1 (0.992); RNR1 (0.985); MRC1 (0.937); DIF1 (0.911); RAD9 (0.907); LCD1 (0.905); RNR2 (0.899); TEL1 (0.897); RNR3 (0.836); CHK1 (0.827); WTM1 (0.81); PIF1 (0.774); RRM3 (0.767); HUG1 (0.749); RNR4 (0.745); MUB1 (0.74); IXR1 (0.717); RAD52 (0.714)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:153123-153437:+ gene-YML058W_AKU4011 rna-NM_001182417.1_AKU4011 cds-NP_013653.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:322740-323054:- gene-YML058W_BG1 rna-NM_001182417.1_BG1 cds-NP_013653.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:159258-159572:+ gene-YML058W_Bruggeman rna-NM_001182417.1_Bruggeman cds-NP_013653.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:160923-161237:+ gene-YML058W_CAT1 rna-NM_001182417.1_CAT1 cds-NP_013653.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:153134-153448:+ gene-YML058W_CBS1585 rna-NM_001182417.1_CBS1585 cds-NP_013653.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:159019-159333:+ gene-YML058W_CBS436 rna-NM_001182417.1_CBS436 cds-NP_013653.1_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:153842-154156:+ gene-YML058W_CBS6412 rna-NM_001182417.1_CBS6412 cds-NP_013653.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:152316-152630:+ gene-YML058W_CBS6413 rna-NM_001182417.1_CBS6413 cds-NP_013653.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:154098-154412:+ gene-YML058W_CENPK1137D rna-NM_001182417.1_CENPK1137D cds-NP_013653.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:153397-153711:+ gene-YML058W_EthanolRed rna-NM_001182417.1_EthanolRed cds-NP_013653.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:153902-154216:+ gene-YML058W_FaliES1 rna-NM_001182417.1_FaliES1 cds-NP_013653.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000366.1:2911-3225:- gene-YML058W_JAY291 rna-NM_001182417.1_JAY291 cds-NP_013653.1_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:157777-158091:+ gene-YML058W_MUCL30387 rna-NM_001182417.1_MUCL30387 cds-NP_013653.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:160965-161279:+ gene-YML058W_MUCL30388 rna-NM_001182417.1_MUCL30388 cds-NP_013653.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:153144-153458:+ gene-YML058W_MUCL39482 rna-NM_001182417.1_MUCL39482 cds-NP_013653.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:158962-159276:+ gene-YML058W_MUCL42920 rna-NM_001182417.1_MUCL42920 cds-NP_013653.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:159337-159651:+ gene-YML058W_NCIM3186 rna-NM_001182417.1_NCIM3186 cds-NP_013653.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:153937-154251:+ gene-YML058W_NCYC1407 rna-NM_001182417.1_NCYC1407 cds-NP_013653.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:159330-159644:+ gene-YML058W_PE2H3 rna-NM_001182417.1_PE2H3 cds-NP_013653.1_PE2H3 99.6 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:159194-159508:+ gene-YML058W_PE2H4 rna-NM_001182417.1_PE2H4 cds-NP_013653.1_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:159383-159697:+ gene-YML058W_S288C rna-NM_001182417.1_S288C cds-NP_013653.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000041.1:24526-24840:- gene-YML058W_SA1 rna-NM_001182417.1_SA1 cds-NP_013653.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:153195-153509:+ gene-YML058W_ThermosaccDry rna-NM_001182417.1_ThermosaccDry cds-NP_013653.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:157543-157857:+ gene-YML058W_VR1 rna-NM_001182417.1_VR1 cds-NP_013653.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:132728-133042:+ gene-YML058W_ZTW1 rna-NM_001182417.1_ZTW1 cds-NP_013653.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:164340-164660:+ gene-YML058W_Sparadoxus rna-NM_001182417.1_Sparadoxus cds-NP_013653.1_Sparadoxus 90.3 100.0 Verified 1 1 1 False True False False False

Additional files