Gene name: SMK1
Reference locus (S288C): YPR054W
Gene biotype: protein_coding
Description: Middle sporulation-specific mitogen-activated protein kinase (MAPK); required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p
Top 10 interactors (score): STE7 (0.965); MKK1 (0.96); MKK2 (0.958); ACA1 (0.956); SKO1 (0.956); PBS2 (0.955); GCN4 (0.954); SPO1 (0.954); SKM1 (0.945); GPA1 (0.941); GPA2 (0.941); STE20 (0.94); CLA4 (0.94); PLB1 (0.938); PLB3 (0.938); PLB2 (0.938); CRM1 (0.922); SSP2 (0.913); GSC2 (0.843); RLM1 (0.814)
Homologues (species, bitscore): MAPK7 (Homo sapiens, 275.4); Mapk7 (Mus musculus, 274.6); mapk7 (Danio rerio, 269.6); mapk7 (Xenopus tropicalis, 278.9); rl (Drosophila melanogaster, 242.3); mpk-1 (Caenorhabditis elegans, 242.3); MPK6 (Arabidopsis thaliana, 251.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:637945-639111:+ | gene-YPR054W_AKU4011 | rna-NM_001184151.1_AKU4011 | cds-NP_015379.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:258568-259734:- | gene-YPR054W_BG1 | rna-NM_001184151.1_BG1 | cds-NP_015379.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:715614-716780:+ | gene-YPR054W_Bruggeman | rna-NM_001184151.1_Bruggeman | cds-NP_015379.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:759068-760234:+ | gene-YPR054W_CAT1 | rna-NM_001184151.1_CAT1 | cds-NP_015379.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:641631-642797:+ | gene-YPR054W_CBS1585 | rna-NM_001184151.1_CBS1585 | cds-NP_015379.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:656010-657176:+ | gene-YPR054W_CBS436 | rna-NM_001184151.1_CBS436 | cds-NP_015379.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:645379-646545:+ | gene-YPR054W_CBS6412 | rna-NM_001184151.1_CBS6412 | cds-NP_015379.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:638580-639746:+ | gene-YPR054W_CBS6413 | rna-NM_001184151.1_CBS6413 | cds-NP_015379.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:666245-667411:+ | gene-YPR054W_CENPK1137D | rna-NM_001184151.1_CENPK1137D | cds-NP_015379.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:965136-966302:+ | gene-YPR054W_EthanolRed | rna-NM_001184151.1_EthanolRed | cds-NP_015379.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:643773-644939:+ | gene-YPR054W_FaliES1 | rna-NM_001184151.1_FaliES1 | cds-NP_015379.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:15731-16897:+ | gene-YPR054W_JAY291 | rna-NM_001184151.1_JAY291 | cds-NP_015379.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:656875-658041:+ | gene-YPR054W_MUCL30387 | rna-NM_001184151.1_MUCL30387 | cds-NP_015379.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:655579-656745:+ | gene-YPR054W_MUCL30388 | rna-NM_001184151.1_MUCL30388 | cds-NP_015379.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:634888-636054:+ | gene-YPR054W_MUCL39482 | rna-NM_001184151.1_MUCL39482 | cds-NP_015379.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:697716-698882:+ | gene-YPR054W_MUCL42920 | rna-NM_001184151.1_MUCL42920 | cds-NP_015379.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:666263-667429:+ | gene-YPR054W_NCIM3186 | rna-NM_001184151.1_NCIM3186 | cds-NP_015379.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:642818-643984:+ | gene-YPR054W_NCYC1407 | rna-NM_001184151.1_NCYC1407 | cds-NP_015379.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:649034-650200:+ | gene-YPR054W_PE2H3 | rna-NM_001184151.1_PE2H3 | cds-NP_015379.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:648682-649848:+ | gene-YPR054W_PE2H4 | rna-NM_001184151.1_PE2H4 | cds-NP_015379.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:666280-667446:+ | gene-YPR054W_S288C | rna-NM_001184151.1_S288C | cds-NP_015379.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:33245-34411:- | gene-YPR054W_SA1 | rna-NM_001184151.1_SA1 | cds-NP_015379.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:643548-644714:+ | gene-YPR054W_ThermosaccDry | rna-NM_001184151.1_ThermosaccDry | cds-NP_015379.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:659707-660873:+ | gene-YPR054W_VR1 | rna-NM_001184151.1_VR1 | cds-NP_015379.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:642779-643945:+ | gene-YPR054W_ZTW1 | rna-NM_001184151.1_ZTW1 | cds-NP_015379.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:643574-644740:+ | gene-YPR054W_Sparadoxus | rna-NM_001184151.1_Sparadoxus | cds-NP_015379.1_Sparadoxus | 90.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |