SMF3 (YLR034C)


Gene profile

Gene name: SMF3
Reference locus (S288C): YLR034C
Gene biotype: protein_coding

Description: Iron transporter SMF3; Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): FET5 (0.956); MRS4 (0.946); CCC1 (0.93); FET3 (0.93); FTR1 (0.922); FTH1 (0.886); CCC2 (0.877); MRS3 (0.869); AFT1 (0.857); AFT2 (0.82); COT1 (0.813); FET4 (0.806); ATX1 (0.787); MMT1 (0.785); TIS11 (0.756); SMX3 (0.753); SIT1 (0.735); FRE1 (0.733); ARN1 (0.727); CTR2 (0.718)

Homologues (species, bitscore): SLC11A2 (Homo sapiens, 191.0); Slc11a2 (Mus musculus, 189.9); slc11a2 (Danio rerio, 63.5); slc11a1 (Xenopus tropicalis, 184.1); Mvl (Drosophila melanogaster, 188.7); smf-1 (Caenorhabditis elegans, 179.5); NRAMP1 (Arabidopsis thaliana, 238.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:198447-199868:- gene-YLR034C_AKU4011 rna-NM_001181921.2_AKU4011 cds-NP_013134.1_AKU4011 98.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:161727-163148:- gene-YLR034C_BG1 rna-NM_001181921.2_BG1 cds-NP_013134.1_BG1 99.3 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:208839-210260:- gene-YLR034C_Bruggeman rna-NM_001181921.2_Bruggeman cds-NP_013134.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:209163-210584:- gene-YLR034C_CAT1 rna-NM_001181921.2_CAT1 cds-NP_013134.1_CAT1 98.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:206073-207494:- gene-YLR034C_CBS1585 rna-NM_001181921.2_CBS1585 cds-NP_013134.1_CBS1585 98.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:196703-198124:- gene-YLR034C_CBS436 rna-NM_001181921.2_CBS436 cds-NP_013134.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:204482-205903:- gene-YLR034C_CBS6412 rna-NM_001181921.2_CBS6412 cds-NP_013134.1_CBS6412 99.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:206334-207755:- gene-YLR034C_CBS6413 rna-NM_001181921.2_CBS6413 cds-NP_013134.1_CBS6413 98.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:195745-197166:- gene-YLR034C_CENPK1137D rna-NM_001181921.2_CENPK1137D cds-NP_013134.1_CENPK1137D 99.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:198458-199879:- gene-YLR034C_EthanolRed rna-NM_001181921.2_EthanolRed cds-NP_013134.1_EthanolRed 98.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:198367-199788:- gene-YLR034C_FaliES1 rna-NM_001181921.2_FaliES1 cds-NP_013134.1_FaliES1 98.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000431.1:42221-43642:- gene-YLR034C_JAY291 rna-NM_001181921.2_JAY291 cds-NP_013134.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:206192-207613:- gene-YLR034C_MUCL30387 rna-NM_001181921.2_MUCL30387 cds-NP_013134.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:213195-214616:- gene-YLR034C_MUCL30388 rna-NM_001181921.2_MUCL30388 cds-NP_013134.1_MUCL30388 99.0 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:206568-207989:- gene-YLR034C_MUCL39482 rna-NM_001181921.2_MUCL39482 cds-NP_013134.1_MUCL39482 98.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:206471-207892:- gene-YLR034C_MUCL42920 rna-NM_001181921.2_MUCL42920 cds-NP_013134.1_MUCL42920 99.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:210486-211907:- gene-YLR034C_NCIM3186 rna-NM_001181921.2_NCIM3186 cds-NP_013134.1_NCIM3186 98.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:198627-200048:- gene-YLR034C_NCYC1407 rna-NM_001181921.2_NCYC1407 cds-NP_013134.1_NCYC1407 98.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:204501-205922:- gene-YLR034C_PE2H3 rna-NM_001181921.2_PE2H3 cds-NP_013134.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:204242-205663:- gene-YLR034C_PE2H4 rna-NM_001181921.2_PE2H4 cds-NP_013134.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:210512-211933:- gene-YLR034C_S288C rna-NM_001181921.2_S288C cds-NP_013134.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000046.1:42349-43770:- gene-YLR034C_SA1 rna-NM_001181921.2_SA1 cds-NP_013134.1_SA1 98.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:198533-199954:- gene-YLR034C_ThermosaccDry rna-NM_001181921.2_ThermosaccDry cds-NP_013134.1_ThermosaccDry 98.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:211951-213372:- gene-YLR034C_VR1 rna-NM_001181921.2_VR1 cds-NP_013134.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:197899-199320:- gene-YLR034C_ZTW1 rna-NM_001181921.2_ZTW1 cds-NP_013134.1_ZTW1 98.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:206689-208110:- gene-YLR034C_Sparadoxus rna-NM_001181921.2_Sparadoxus cds-NP_013134.1_Sparadoxus 90.5 99.9 Verified 1 1 1 False True False False False

Additional files