SMF2 (YHR050W)


Gene profile

Gene name: SMF2
Reference locus (S288C): YHR050W
Gene biotype: protein_coding

Description: Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins

Top 10 interactors (score): MTM1 (0.93); SOD2 (0.924); BSD2 (0.902); SMX3 (0.865); PMR1 (0.845); CCC1 (0.805); FET4 (0.804); YPK9 (0.803); CDC1 (0.777); PHO84 (0.776); GDT1 (0.719); FET3 (0.689); PPN1 (0.671); VTC4 (0.671); FTR1 (0.659); SPF1 (0.644); CTR2 (0.643); PCA1 (0.616); AFT1 (0.596); CTR3 (0.589)

Homologues (species, bitscore): SLC11A2 (Homo sapiens, 190.3); Slc11a2 (Mus musculus, 190.3); slc11a2 (Danio rerio, 57.4); slc11a2 (Xenopus tropicalis, 191.8); Mvl (Drosophila melanogaster, 178.7); smf-1 (Caenorhabditis elegans, 177.9); NRAMP1 (Arabidopsis thaliana, 234.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:195916-197565:+ gene-YHR050W_AKU4011 rna-NM_001179180.1_AKU4011 cds-NP_011917.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:116172-117821:+ gene-YHR050W_BG1 rna-NM_001179180.1_BG1 cds-NP_011917.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:203669-205318:+ gene-YHR050W_Bruggeman rna-NM_001179180.1_Bruggeman cds-NP_011917.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:198463-200112:+ gene-YHR050W_CAT1 rna-NM_001179180.1_CAT1 cds-NP_011917.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:195022-196671:+ gene-YHR050W_CBS1585 rna-NM_001179180.1_CBS1585 cds-NP_011917.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:190530-192179:+ gene-YHR050W_CBS436 rna-NM_001179180.1_CBS436 cds-NP_011917.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:195254-196903:+ gene-YHR050W_CBS6412 rna-NM_001179180.1_CBS6412 cds-NP_011917.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:196087-197736:+ gene-YHR050W_CBS6413 rna-NM_001179180.1_CBS6413 cds-NP_011917.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:200915-202564:+ gene-YHR050W_CENPK1137D rna-NM_001179180.1_CENPK1137D cds-NP_011917.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:195414-197063:+ gene-YHR050W_EthanolRed rna-NM_001179180.1_EthanolRed cds-NP_011917.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:196391-198040:+ gene-YHR050W_FaliES1 rna-NM_001179180.1_FaliES1 cds-NP_011917.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000244.1:13143-14792:+ gene-YHR050W_JAY291 rna-NM_001179180.1_JAY291 cds-NP_011917.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:203128-204777:+ gene-YHR050W_MUCL30387 rna-NM_001179180.1_MUCL30387 cds-NP_011917.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:203303-204952:+ gene-YHR050W_MUCL30388 rna-NM_001179180.1_MUCL30388 cds-NP_011917.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:195307-196956:+ gene-YHR050W_MUCL39482 rna-NM_001179180.1_MUCL39482 cds-NP_011917.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:202212-203861:+ gene-YHR050W_MUCL42920 rna-NM_001179180.1_MUCL42920 cds-NP_011917.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:207536-209185:+ gene-YHR050W_NCIM3186 rna-NM_001179180.1_NCIM3186 cds-NP_011917.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:195322-196971:+ gene-YHR050W_NCYC1407 rna-NM_001179180.1_NCYC1407 cds-NP_011917.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:197510-199159:+ gene-YHR050W_PE2H3 rna-NM_001179180.1_PE2H3 cds-NP_011917.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:204957-206606:+ gene-YHR050W_PE2H4 rna-NM_001179180.1_PE2H4 cds-NP_011917.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:207654-209303:+ gene-YHR050W_S288C rna-NM_001179180.1_S288C cds-NP_011917.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:149291-150940:- gene-YHR050W_SA1 rna-NM_001179180.1_SA1 cds-NP_011917.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:197482-199131:+ gene-YHR050W_ThermosaccDry rna-NM_001179180.1_ThermosaccDry cds-NP_011917.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:204014-205663:+ gene-YHR050W_VR1 rna-NM_001179180.1_VR1 cds-NP_011917.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:189027-190676:+ gene-YHR050W_ZTW1 rna-NM_001179180.1_ZTW1 cds-NP_011917.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:194595-196247:+ gene-YHR050W_Sparadoxus rna-NM_001179180.1_Sparadoxus cds-NP_011917.1_Sparadoxus 89.5 100.0 Verified 1 1 1 False True False False False

Additional files