SMD1 (YGR074W)


Gene profile

Gene name: SMD1
Reference locus (S288C): YGR074W
Gene biotype: protein_coding

Description: Small nuclear ribonucleoprotein Sm D1; Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; relocalizes to the cytosol in response to hypoxia; homolog of human Sm D1; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): SMD3 (0.999); SMB1 (0.999); CEF1 (0.999); PRP6 (0.999); SMD2 (0.999); SNU66 (0.999); PRP9 (0.999); LSM5 (0.999); BRR2 (0.999); PRP8 (0.999); SMX2 (0.999); CWC2 (0.999); SMX3 (0.999); SNU114 (0.999); RSE1 (0.999); LSM8 (0.999); LSM2 (0.999); PRP19 (0.999); YHC1 (0.999); LEA1 (0.999)

Homologues (species, bitscore): SNRPD1 (Homo sapiens, 75.5); Snrpd1 (Mus musculus, 75.5); snrpd1 (Danio rerio, 77.0); snrpd1 (Xenopus tropicalis, 73.9); SmD1 (Drosophila melanogaster, 72.8); snr-3 (Caenorhabditis elegans, 68.9); AT3G07590 (Arabidopsis thaliana, 76.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:619403-619843:+ gene-YGR074W_AKU4011 rna-NM_001181203.3_AKU4011 cds-NP_011588.3_AKU4011 99.3 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000173.1:55672-56112:+ gene-YGR074W_BG1 rna-NM_001181203.3_BG1 cds-NP_011588.3_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:621679-622119:+ gene-YGR074W_Bruggeman rna-NM_001181203.3_Bruggeman cds-NP_011588.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:620111-620551:+ gene-YGR074W_CAT1 rna-NM_001181203.3_CAT1 cds-NP_011588.3_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:620697-621137:+ gene-YGR074W_CBS1585 rna-NM_001181203.3_CBS1585 cds-NP_011588.3_CBS1585 99.3 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:622009-622449:+ gene-YGR074W_CBS436 rna-NM_001181203.3_CBS436 cds-NP_011588.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:613522-613962:+ gene-YGR074W_CBS6412 rna-NM_001181203.3_CBS6412 cds-NP_011588.3_CBS6412 99.3 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:617405-617845:+ gene-YGR074W_CBS6413 rna-NM_001181203.3_CBS6413 cds-NP_011588.3_CBS6413 99.3 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:635418-635858:+ gene-YGR074W_CENPK1137D rna-NM_001181203.3_CENPK1137D cds-NP_011588.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:607656-608096:+ gene-YGR074W_EthanolRed rna-NM_001181203.3_EthanolRed cds-NP_011588.3_EthanolRed 99.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:611123-611563:+ gene-YGR074W_FaliES1 rna-NM_001181203.3_FaliES1 cds-NP_011588.3_FaliES1 99.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000435.1:62059-62499:+ gene-YGR074W_JAY291 rna-NM_001181203.3_JAY291 cds-NP_011588.3_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:618339-618779:+ gene-YGR074W_MUCL30387 rna-NM_001181203.3_MUCL30387 cds-NP_011588.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:621709-622149:+ gene-YGR074W_MUCL30388 rna-NM_001181203.3_MUCL30388 cds-NP_011588.3_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:616548-616988:+ gene-YGR074W_MUCL39482 rna-NM_001181203.3_MUCL39482 cds-NP_011588.3_MUCL39482 99.3 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:626340-626780:+ gene-YGR074W_MUCL42920 rna-NM_001181203.3_MUCL42920 cds-NP_011588.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:635712-636152:+ gene-YGR074W_NCIM3186 rna-NM_001181203.3_NCIM3186 cds-NP_011588.3_NCIM3186 99.3 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:610729-611169:+ gene-YGR074W_NCYC1407 rna-NM_001181203.3_NCYC1407 cds-NP_011588.3_NCYC1407 99.3 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:613964-614404:+ gene-YGR074W_PE2H3 rna-NM_001181203.3_PE2H3 cds-NP_011588.3_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:619088-619528:+ gene-YGR074W_PE2H4 rna-NM_001181203.3_PE2H4 cds-NP_011588.3_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:635712-636152:+ gene-YGR074W_S288C rna-NM_001181203.3_S288C cds-NP_011588.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000015.1:62254-62694:+ gene-YGR074W_SA1 rna-NM_001181203.3_SA1 cds-NP_011588.3_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:630449-630889:+ gene-YGR074W_ThermosaccDry rna-NM_001181203.3_ThermosaccDry cds-NP_011588.3_ThermosaccDry 99.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:727409-727849:+ gene-YGR074W_VR1 rna-NM_001181203.3_VR1 cds-NP_011588.3_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000015.1:85919-86359:+ gene-YGR074W_ZTW1 rna-NM_001181203.3_ZTW1 cds-NP_011588.3_ZTW1 99.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:620987-621427:+ gene-YGR074W_Sparadoxus rna-NM_001181203.3_Sparadoxus cds-NP_011588.3_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files