Gene name: SMC6
Reference locus (S288C): YLR383W
Gene biotype: protein_coding
Description: Structural maintenance of chromosomes protein 6; Component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; homologous to S. pombe rad18
Top 10 interactors (score): NSE4 (0.999); NSE1 (0.999); MMS21 (0.999); SMC5 (0.999); RTT107 (0.999); SMC3 (0.999); NSE3 (0.999); SMC4 (0.998); SMC1 (0.996); NSE5 (0.995); KRE29 (0.994); IRR1 (0.994); MCD1 (0.993); TOP2 (0.993); SMC2 (0.99); RAD51 (0.987); SGS1 (0.985); SMT3 (0.984); UBC9 (0.983); MPH1 (0.982)
Homologues (species, bitscore): SMC6 (Homo sapiens, 317.0); Smc6 (Mus musculus, 310.5); SMC6 (Danio rerio, 327.4); smc6 (Xenopus tropicalis, 339.7); jnj (Drosophila melanogaster, 225.7); smc-6 (Caenorhabditis elegans, 214.2); MIM (Arabidopsis thaliana, 312.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:834825-838169:+ | gene-YLR383W_AKU4011 | rna-NM_001182272.1_AKU4011 | cds-NP_013487.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:67003-70347:+ | gene-YLR383W_BG1 | rna-NM_001182272.1_BG1 | cds-NP_013487.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:873131-876475:+ | gene-YLR383W_Bruggeman | rna-NM_001182272.1_Bruggeman | cds-NP_013487.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:868656-872000:+ | gene-YLR383W_CAT1 | rna-NM_001182272.1_CAT1 | cds-NP_013487.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:870421-873765:+ | gene-YLR383W_CBS1585 | rna-NM_001182272.1_CBS1585 | cds-NP_013487.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:854061-857405:+ | gene-YLR383W_CBS436 | rna-NM_001182272.1_CBS436 | cds-NP_013487.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:906462-909806:+ | gene-YLR383W_CBS6412 | rna-NM_001182272.1_CBS6412 | cds-NP_013487.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:870712-874056:+ | gene-YLR383W_CBS6413 | rna-NM_001182272.1_CBS6413 | cds-NP_013487.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:870066-873410:+ | gene-YLR383W_CENPK1137D | rna-NM_001182272.1_CENPK1137D | cds-NP_013487.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:827367-830711:+ | gene-YLR383W_EthanolRed | rna-NM_001182272.1_EthanolRed | cds-NP_013487.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:856677-860021:+ | gene-YLR383W_FaliES1 | rna-NM_001182272.1_FaliES1 | cds-NP_013487.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000434.1:9836-13180:+ | gene-YLR383W_JAY291 | rna-NM_001182272.1_JAY291 | cds-NP_013487.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:871642-874986:+ | gene-YLR383W_MUCL30387 | rna-NM_001182272.1_MUCL30387 | cds-NP_013487.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:878082-881426:+ | gene-YLR383W_MUCL30388 | rna-NM_001182272.1_MUCL30388 | cds-NP_013487.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:871641-874985:+ | gene-YLR383W_MUCL39482 | rna-NM_001182272.1_MUCL39482 | cds-NP_013487.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:866298-869642:+ | gene-YLR383W_MUCL42920 | rna-NM_001182272.1_MUCL42920 | cds-NP_013487.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:885262-888606:+ | gene-YLR383W_NCIM3186 | rna-NM_001182272.1_NCIM3186 | cds-NP_013487.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:880821-884165:+ | gene-YLR383W_NCYC1407 | rna-NM_001182272.1_NCYC1407 | cds-NP_013487.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:867215-870559:+ | gene-YLR383W_PE2H3 | rna-NM_001182272.1_PE2H3 | cds-NP_013487.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:866959-870303:+ | gene-YLR383W_PE2H4 | rna-NM_001182272.1_PE2H4 | cds-NP_013487.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:885288-888632:+ | gene-YLR383W_S288C | rna-NM_001182272.1_S288C | cds-NP_013487.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:160056-163400:- | gene-YLR383W_SA1 | rna-NM_001182272.1_SA1 | cds-NP_013487.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:859756-863100:+ | gene-YLR383W_ThermosaccDry | rna-NM_001182272.1_ThermosaccDry | cds-NP_013487.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:872305-875649:+ | gene-YLR383W_VR1 | rna-NM_001182272.1_VR1 | cds-NP_013487.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:196473-199817:+ | gene-YLR383W_ZTW1 | rna-NM_001182272.1_ZTW1 | cds-NP_013487.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:845140-848484:+ | gene-YLR383W_Sparadoxus | rna-NM_001182272.1_Sparadoxus | cds-NP_013487.1_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |