Gene name: SMC4
Reference locus (S288C): YLR086W
Gene biotype: protein_coding
Description: Structural maintenance of chromosomes protein 4; Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for tRNA gene clustering at the nucleolus; potential Cdc28p substrate; Belongs to the SMC family. SMC4 subfamily
Top 10 interactors (score): YCS4 (0.999); BRN1 (0.999); SMC2 (0.999); YCG1 (0.999); SMC6 (0.998); SMC5 (0.998); IRR1 (0.998); PDS5 (0.997); TOP2 (0.996); ESP1 (0.993); IPL1 (0.99); MCM3 (0.988); SMC1 (0.987); MCD1 (0.986); NDC80 (0.983); MCM7 (0.979); NUF2 (0.977); SMC3 (0.975); CDC5 (0.972); SCC2 (0.97)
Homologues (species, bitscore): SMC4 (Homo sapiens, 746.1); Smc4 (Mus musculus, 752.3); smc4 (Danio rerio, 769.6); smc4 (Xenopus tropicalis, 754.6); glu (Drosophila melanogaster, 689.5); smc-4 (Caenorhabditis elegans, 518.5); SMC3 (Arabidopsis thaliana, 738.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:284715-288971:+ | gene-YLR086W_AKU4011 | rna-NM_001181973.1_AKU4011 | cds-NP_013187.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:247885-252141:+ | gene-YLR086W_BG1 | rna-NM_001181973.1_BG1 | cds-NP_013187.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:294623-298879:+ | gene-YLR086W_Bruggeman | rna-NM_001181973.1_Bruggeman | cds-NP_013187.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:294942-299198:+ | gene-YLR086W_CAT1 | rna-NM_001181973.1_CAT1 | cds-NP_013187.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:291829-296085:+ | gene-YLR086W_CBS1585 | rna-NM_001181973.1_CBS1585 | cds-NP_013187.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:282453-286709:+ | gene-YLR086W_CBS436 | rna-NM_001181973.1_CBS436 | cds-NP_013187.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:290270-294526:+ | gene-YLR086W_CBS6412 | rna-NM_001181973.1_CBS6412 | cds-NP_013187.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:292101-296357:+ | gene-YLR086W_CBS6413 | rna-NM_001181973.1_CBS6413 | cds-NP_013187.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:287253-291509:+ | gene-YLR086W_CENPK1137D | rna-NM_001181973.1_CENPK1137D | cds-NP_013187.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:284234-288490:+ | gene-YLR086W_EthanolRed | rna-NM_001181973.1_EthanolRed | cds-NP_013187.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:284110-288366:+ | gene-YLR086W_FaliES1 | rna-NM_001181973.1_FaliES1 | cds-NP_013187.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:59049-63304:+ | gene-YLR086W_JAY291 | rna-NM_001181973.1_JAY291 | cds-NP_013187.1_JAY291 | 99.3 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:291988-296244:+ | gene-YLR086W_MUCL30387 | rna-NM_001181973.1_MUCL30387 | cds-NP_013187.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:299636-303892:+ | gene-YLR086W_MUCL30388 | rna-NM_001181973.1_MUCL30388 | cds-NP_013187.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:292347-296603:+ | gene-YLR086W_MUCL39482 | rna-NM_001181973.1_MUCL39482 | cds-NP_013187.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:292270-296526:+ | gene-YLR086W_MUCL42920 | rna-NM_001181973.1_MUCL42920 | cds-NP_013187.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:302217-306473:+ | gene-YLR086W_NCIM3186 | rna-NM_001181973.1_NCIM3186 | cds-NP_013187.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:284418-288674:+ | gene-YLR086W_NCYC1407 | rna-NM_001181973.1_NCYC1407 | cds-NP_013187.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:290279-294535:+ | gene-YLR086W_PE2H3 | rna-NM_001181973.1_PE2H3 | cds-NP_013187.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:290020-294276:+ | gene-YLR086W_PE2H4 | rna-NM_001181973.1_PE2H4 | cds-NP_013187.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:302243-306499:+ | gene-YLR086W_S288C | rna-NM_001181973.1_S288C | cds-NP_013187.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000033.1:67619-71875:- | gene-YLR086W_SA1 | rna-NM_001181973.1_SA1 | cds-NP_013187.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:284286-288542:+ | gene-YLR086W_ThermosaccDry | rna-NM_001181973.1_ThermosaccDry | cds-NP_013187.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:298471-302727:+ | gene-YLR086W_VR1 | rna-NM_001181973.1_VR1 | cds-NP_013187.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:283668-287924:+ | gene-YLR086W_ZTW1 | rna-NM_001181973.1_ZTW1 | cds-NP_013187.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:292512-296768:+ | gene-YLR086W_Sparadoxus | rna-NM_001181973.1_Sparadoxus | cds-NP_013187.1_Sparadoxus | 88.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |