Gene name: SMC3
Reference locus (S288C): YJL074C
Gene biotype: protein_coding
Description: Structural maintenance of chromosomes protein 3; Subunit of the multiprotein cohesin complex; required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member
Top 10 interactors (score): PDS5 (0.999); IRR1 (0.999); ESP1 (0.999); SMC1 (0.999); ECO1 (0.999); RAD61 (0.999); SMC2 (0.999); MCD1 (0.999); SMC5 (0.999); SCC2 (0.999); SMC6 (0.999); CDC5 (0.998); CTF4 (0.997); CTF18 (0.995); TOF1 (0.992); TOP2 (0.99); NDC80 (0.989); MMS21 (0.988); RAD50 (0.986); NSE3 (0.986)
Homologues (species, bitscore): SMC3 (Homo sapiens, 642.9); Smc3 (Mus musculus, 644.8); smc3 (Danio rerio, 630.9); smc3 (Xenopus tropicalis, 636.3); SMC3 (Drosophila melanogaster, 552.0); smc-3 (Caenorhabditis elegans, 493.4); TTN7 (Arabidopsis thaliana, 599.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:282024-285716:- | gene-YJL074C_AKU4011 | rna-NM_001181507.1_AKU4011 | cds-NP_012461.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:328796-332488:+ | gene-YJL074C_BG1 | rna-NM_001181507.1_BG1 | cds-NP_012461.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:294563-298255:- | gene-YJL074C_Bruggeman | rna-NM_001181507.1_Bruggeman | cds-NP_012461.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:298663-302355:- | gene-YJL074C_CAT1 | rna-NM_001181507.1_CAT1 | cds-NP_012461.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:293682-297374:- | gene-YJL074C_CBS1585 | rna-NM_001181507.1_CBS1585 | cds-NP_012461.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:311689-315381:- | gene-YJL074C_CBS436 | rna-NM_001181507.1_CBS436 | cds-NP_012461.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:282782-286474:- | gene-YJL074C_CBS6412 | rna-NM_001181507.1_CBS6412 | cds-NP_012461.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:284138-287830:- | gene-YJL074C_CBS6413 | rna-NM_001181507.1_CBS6413 | cds-NP_012461.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:281627-285319:- | gene-YJL074C_CENPK1137D | rna-NM_001181507.1_CENPK1137D | cds-NP_012461.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:285862-289554:- | gene-YJL074C_EthanolRed | rna-NM_001181507.1_EthanolRed | cds-NP_012461.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:297437-301129:- | gene-YJL074C_FaliES1 | rna-NM_001181507.1_FaliES1 | cds-NP_012461.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:95021-98713:- | gene-YJL074C_JAY291 | rna-NM_001181507.1_JAY291 | cds-NP_012461.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:295720-299412:- | gene-YJL074C_MUCL30387 | rna-NM_001181507.1_MUCL30387 | cds-NP_012461.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:291756-295448:- | gene-YJL074C_MUCL30388 | rna-NM_001181507.1_MUCL30388 | cds-NP_012461.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:286434-290126:- | gene-YJL074C_MUCL39482 | rna-NM_001181507.1_MUCL39482 | cds-NP_012461.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:293084-296776:- | gene-YJL074C_MUCL42920 | rna-NM_001181507.1_MUCL42920 | cds-NP_012461.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:299136-302828:- | gene-YJL074C_NCIM3186 | rna-NM_001181507.1_NCIM3186 | cds-NP_012461.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:285130-288822:- | gene-YJL074C_NCYC1407 | rna-NM_001181507.1_NCYC1407 | cds-NP_012461.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:297484-301176:- | gene-YJL074C_PE2H3 | rna-NM_001181507.1_PE2H3 | cds-NP_012461.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:297128-300820:- | gene-YJL074C_PE2H4 | rna-NM_001181507.1_PE2H4 | cds-NP_012461.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:299157-302849:- | gene-YJL074C_S288C | rna-NM_001181507.1_S288C | cds-NP_012461.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:95046-98738:- | gene-YJL074C_SA1 | rna-NM_001181507.1_SA1 | cds-NP_012461.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:290850-294542:- | gene-YJL074C_ThermosaccDry | rna-NM_001181507.1_ThermosaccDry | cds-NP_012461.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:293027-296719:- | gene-YJL074C_VR1 | rna-NM_001181507.1_VR1 | cds-NP_012461.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:272236-275928:- | gene-YJL074C_ZTW1 | rna-NM_001181507.1_ZTW1 | cds-NP_012461.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:296242-299934:- | gene-YJL074C_Sparadoxus | rna-NM_001181507.1_Sparadoxus | cds-NP_012461.1_Sparadoxus | 90.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |