SMC2 (YFR031C)


Gene profile

Gene name: SMC2
Reference locus (S288C): YFR031C
Gene biotype: protein_coding

Description: Structural maintenance of chromosomes protein 2; Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus

Top 10 interactors (score): SMC4 (0.999); BRN1 (0.999); SMC3 (0.999); SMC1 (0.999); YCG1 (0.999); YCS4 (0.999); SMC5 (0.995); MCD1 (0.994); IRR1 (0.993); TOP2 (0.992); SMC6 (0.99); NDC80 (0.987); ESP1 (0.977); IPL1 (0.976); POL1 (0.964); MCM2 (0.964); POL3 (0.957); MCM7 (0.954); BUB1 (0.949); POL12 (0.945)

Homologues (species, bitscore): SMC2 (Homo sapiens, 733.4); Smc2 (Mus musculus, 732.3); smc2 (Danio rerio, 746.5); smc2 (Xenopus tropicalis, 703.4); SMC2 (Drosophila melanogaster, 642.9); mix-1 (Caenorhabditis elegans, 478.4); SMC2 (Arabidopsis thaliana, 719.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:206743-210255:- gene-YFR031C_AKU4011 rna-NM_001179996.2_AKU4011 cds-NP_116687.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000071.1:50781-54293:+ gene-YFR031C_BG1 rna-NM_001179996.2_BG1 cds-NP_116687.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:210400-213912:- gene-YFR031C_Bruggeman rna-NM_001179996.2_Bruggeman cds-NP_116687.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:212382-215894:- gene-YFR031C_CAT1 rna-NM_001179996.2_CAT1 cds-NP_116687.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:208233-211745:- gene-YFR031C_CBS1585 rna-NM_001179996.2_CBS1585 cds-NP_116687.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:181204-184716:- gene-YFR031C_CBS436 rna-NM_001179996.2_CBS436 cds-NP_116687.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:207312-210824:- gene-YFR031C_CBS6412 rna-NM_001179996.2_CBS6412 cds-NP_116687.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:209970-213482:- gene-YFR031C_CBS6413 rna-NM_001179996.2_CBS6413 cds-NP_116687.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:212693-216205:- gene-YFR031C_CENPK1137D rna-NM_001179996.2_CENPK1137D cds-NP_116687.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:205850-209362:- gene-YFR031C_EthanolRed rna-NM_001179996.2_EthanolRed cds-NP_116687.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:207501-211013:- gene-YFR031C_FaliES1 rna-NM_001179996.2_FaliES1 cds-NP_116687.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000453.1:10641-14153:- gene-YFR031C_JAY291 rna-NM_001179996.2_JAY291 cds-NP_116687.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:210835-214347:- gene-YFR031C_MUCL30387 rna-NM_001179996.2_MUCL30387 cds-NP_116687.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:206327-209839:- gene-YFR031C_MUCL30388 rna-NM_001179996.2_MUCL30388 cds-NP_116687.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:206153-209665:- gene-YFR031C_MUCL39482 rna-NM_001179996.2_MUCL39482 cds-NP_116687.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:205508-209020:- gene-YFR031C_MUCL42920 rna-NM_001179996.2_MUCL42920 cds-NP_116687.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:216593-220105:- gene-YFR031C_NCIM3186 rna-NM_001179996.2_NCIM3186 cds-NP_116687.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:207035-210547:- gene-YFR031C_NCYC1407 rna-NM_001179996.2_NCYC1407 cds-NP_116687.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:249048-252560:- gene-YFR031C_PE2H3 rna-NM_001179996.2_PE2H3 cds-NP_116687.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:248596-252108:- gene-YFR031C_PE2H4 rna-NM_001179996.2_PE2H4 cds-NP_116687.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:216594-220106:- gene-YFR031C_S288C rna-NM_001179996.2_S288C cds-NP_116687.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:104363-107875:+ gene-YFR031C_SA1 rna-NM_001179996.2_SA1 cds-NP_116687.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:206658-210170:- gene-YFR031C_ThermosaccDry rna-NM_001179996.2_ThermosaccDry cds-NP_116687.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:222420-225932:- gene-YFR031C_VR1 rna-NM_001179996.2_VR1 cds-NP_116687.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:137129-140641:- gene-YFR031C_ZTW1 rna-NM_001179996.2_ZTW1 cds-NP_116687.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:230316-233828:- gene-YFR031C_Sparadoxus rna-NM_001179996.2_Sparadoxus cds-NP_116687.1_Sparadoxus 90.6 100.0 Verified 1 1 1 False True False False False

Additional files