SMC1 (YFL008W)


Gene profile

Gene name: SMC1
Reference locus (S288C): YFL008W
Gene biotype: protein_coding

Description: Structural maintenance of chromosomes protein 1; Subunit of the multiprotein cohesin complex; essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure; Belongs to the SMC family. SMC1 subfamily

Top 10 interactors (score): MCD1 (0.999); SCC2 (0.999); SMC3 (0.999); NDC80 (0.999); SMC2 (0.999); IRR1 (0.999); PDS5 (0.999); SMC5 (0.998); ECO1 (0.998); ESP1 (0.996); SMC6 (0.996); BUB3 (0.99); CDC5 (0.988); SMC4 (0.987); STU2 (0.976); BRN1 (0.971); CTF18 (0.971); YCG1 (0.97); RAD9 (0.97); CRM1 (0.964)

Homologues (species, bitscore): SMC1A (Homo sapiens, 515.0); Smc1a (Mus musculus, 516.5); smc1al (Danio rerio, 521.5); smc1a (Xenopus tropicalis, 501.5); SMC1 (Drosophila melanogaster, 428.3); him-1 (Caenorhabditis elegans, 430.6); TTN8 (Arabidopsis thaliana, 542.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:115838-119515:+ gene-YFL008W_AKU4011 rna-NM_001179958.1_AKU4011 cds-NP_116647.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000079.1:1562-5239:+ gene-YFL008W_BG1 rna-NM_001179958.1_BG1 cds-NP_116647.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:115405-119082:+ gene-YFL008W_Bruggeman rna-NM_001179958.1_Bruggeman cds-NP_116647.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:121391-125068:+ gene-YFL008W_CAT1 rna-NM_001179958.1_CAT1 cds-NP_116647.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:116663-120340:+ gene-YFL008W_CBS1585 rna-NM_001179958.1_CBS1585 cds-NP_116647.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:91334-95011:+ gene-YFL008W_CBS436 rna-NM_001179958.1_CBS436 cds-NP_116647.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:116404-120081:+ gene-YFL008W_CBS6412 rna-NM_001179958.1_CBS6412 cds-NP_116647.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:118914-122591:+ gene-YFL008W_CBS6413 rna-NM_001179958.1_CBS6413 cds-NP_116647.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:115713-119390:+ gene-YFL008W_CENPK1137D rna-NM_001179958.1_CENPK1137D cds-NP_116647.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:114825-118502:+ gene-YFL008W_EthanolRed rna-NM_001179958.1_EthanolRed cds-NP_116647.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:116472-120149:+ gene-YFL008W_FaliES1 rna-NM_001179958.1_FaliES1 cds-NP_116647.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000450.1:1477-5154:+ gene-YFL008W_JAY291 rna-NM_001179958.1_JAY291 cds-NP_116647.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:117037-120714:+ gene-YFL008W_MUCL30387 rna-NM_001179958.1_MUCL30387 cds-NP_116647.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:115007-118684:+ gene-YFL008W_MUCL30388 rna-NM_001179958.1_MUCL30388 cds-NP_116647.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:115107-118784:+ gene-YFL008W_MUCL39482 rna-NM_001179958.1_MUCL39482 cds-NP_116647.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:114371-118048:+ gene-YFL008W_MUCL42920 rna-NM_001179958.1_MUCL42920 cds-NP_116647.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:119428-123105:+ gene-YFL008W_NCIM3186 rna-NM_001179958.1_NCIM3186 cds-NP_116647.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:116122-119799:+ gene-YFL008W_NCYC1407 rna-NM_001179958.1_NCYC1407 cds-NP_116647.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:136011-139688:+ gene-YFL008W_PE2H3 rna-NM_001179958.1_PE2H3 cds-NP_116647.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:135559-139236:+ gene-YFL008W_PE2H4 rna-NM_001179958.1_PE2H4 cds-NP_116647.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:119429-123106:+ gene-YFL008W_S288C rna-NM_001179958.1_S288C cds-NP_116647.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:194332-198009:- gene-YFL008W_SA1 rna-NM_001179958.1_SA1 cds-NP_116647.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:115632-119309:+ gene-YFL008W_ThermosaccDry rna-NM_001179958.1_ThermosaccDry cds-NP_116647.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:125521-129198:+ gene-YFL008W_VR1 rna-NM_001179958.1_VR1 cds-NP_116647.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:46080-49757:+ gene-YFL008W_ZTW1 rna-NM_001179958.1_ZTW1 cds-NP_116647.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:140142-143828:+ gene-YFL008W_Sparadoxus rna-NM_001179958.1_Sparadoxus cds-NP_116647.1_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files