SLY1 (YDR189W)


Gene profile

Gene name: SLY1
Reference locus (S288C): YDR189W
Gene biotype: protein_coding

Description: Hydrophilic protein involved in ER/Golgi vesicle trafficking; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex

Top 10 interactors (score): BET1 (0.999); SED5 (0.999); UFE1 (0.999); SEC22 (0.999); BOS1 (0.998); YKT6 (0.998); COG4 (0.997); SEC18 (0.996); SEC17 (0.994); USE1 (0.993); USO1 (0.991); SEC4 (0.99); GOS1 (0.989); YPT1 (0.988); COG3 (0.978); VPS33 (0.976); SSO1 (0.972); SSO2 (0.965); GRH1 (0.964); SEC23 (0.956)

Homologues (species, bitscore): SCFD1 (Homo sapiens, 364.4); Scfd1 (Mus musculus, 358.2); sly1 (Danio rerio, 369.0); scfd1 (Xenopus tropicalis, 350.5); Slh (Drosophila melanogaster, 347.4); F43D9.3 (Caenorhabditis elegans, 311.2); ATSLY1 (Arabidopsis thaliana, 356.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:806930-808930:+ gene-YDR189W_AKU4011 rna-NM_001180497.1_AKU4011 cds-NP_010475.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:316879-318879:- gene-YDR189W_BG1 rna-NM_001180497.1_BG1 cds-NP_010475.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:839349-841349:+ gene-YDR189W_Bruggeman rna-NM_001180497.1_Bruggeman cds-NP_010475.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:826604-828604:+ gene-YDR189W_CAT1 rna-NM_001180497.1_CAT1 cds-NP_010475.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:797296-799296:+ gene-YDR189W_CBS1585 rna-NM_001180497.1_CBS1585 cds-NP_010475.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:826289-828289:+ gene-YDR189W_CBS436 rna-NM_001180497.1_CBS436 cds-NP_010475.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:794099-796099:+ gene-YDR189W_CBS6412 rna-NM_001180497.1_CBS6412 cds-NP_010475.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:824643-826643:+ gene-YDR189W_CBS6413 rna-NM_001180497.1_CBS6413 cds-NP_010475.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:837233-839233:+ gene-YDR189W_CENPK1137D rna-NM_001180497.1_CENPK1137D cds-NP_010475.1_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:807692-809692:+ gene-YDR189W_EthanolRed rna-NM_001180497.1_EthanolRed cds-NP_010475.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:815904-817904:+ gene-YDR189W_FaliES1 rna-NM_001180497.1_FaliES1 cds-NP_010475.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000068.1:31463-33463:- gene-YDR189W_JAY291 rna-NM_001180497.1_JAY291 cds-NP_010475.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:824994-826994:+ gene-YDR189W_MUCL30387 rna-NM_001180497.1_MUCL30387 cds-NP_010475.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:813237-815237:+ gene-YDR189W_MUCL30388 rna-NM_001180497.1_MUCL30388 cds-NP_010475.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:798743-800743:+ gene-YDR189W_MUCL39482 rna-NM_001180497.1_MUCL39482 cds-NP_010475.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:737436-739436:+ gene-YDR189W_MUCL42920 rna-NM_001180497.1_MUCL42920 cds-NP_010475.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:838315-840315:+ gene-YDR189W_NCIM3186 rna-NM_001180497.1_NCIM3186 cds-NP_010475.1_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:801875-803875:+ gene-YDR189W_NCYC1407 rna-NM_001180497.1_NCYC1407 cds-NP_010475.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:818619-820619:+ gene-YDR189W_PE2H3 rna-NM_001180497.1_PE2H3 cds-NP_010475.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:817924-819924:+ gene-YDR189W_PE2H4 rna-NM_001180497.1_PE2H4 cds-NP_010475.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:838392-840392:+ gene-YDR189W_S288C rna-NM_001180497.1_S288C cds-NP_010475.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:184103-186103:+ gene-YDR189W_SA1 rna-NM_001180497.1_SA1 cds-NP_010475.1_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:814059-816059:+ gene-YDR189W_ThermosaccDry rna-NM_001180497.1_ThermosaccDry cds-NP_010475.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:829284-831284:+ gene-YDR189W_VR1 rna-NM_001180497.1_VR1 cds-NP_010475.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:76772-78772:+ gene-YDR189W_ZTW1 rna-NM_001180497.1_ZTW1 cds-NP_010475.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:818982-820982:+ gene-YDR189W_Sparadoxus rna-NM_001180497.1_Sparadoxus cds-NP_010475.1_Sparadoxus 90.4 100.0 Verified 1 1 1 False True False False False

Additional files