Gene name: SLX5
Reference locus (S288C): YDL013W
Gene biotype: protein_coding
Description: Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex; role in Ub-mediated degradation of histone variant Cse4p preventing mislocalization to euchromatin; role in proteolysis of spindle positioning protein Kar9p, and DNA repair proteins Rad52p and Rad57p; forms SUMO-dependent nuclear foci, including DNA repair centers; contains a RING domain and two SIM motifs; associates with the centromere; required for maintenance of genome integrity like human ortholog RNF4
Top 10 interactors (score): SLX8 (0.999); SMT3 (0.973); SGS1 (0.968); NFI1 (0.967); UBC4 (0.956); ULP2 (0.926); ULP1 (0.914); CDC4 (0.911); ASI3 (0.907); SIZ1 (0.906); ASI1 (0.906); MET30 (0.902); CDC23 (0.902); RAD52 (0.902); SWM1 (0.901); APC1 (0.9); APC11 (0.9); DOC1 (0.9); ASI2 (0.9); APC2 (0.9)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:415151-417010:+ | gene-YDL013W_AKU4011 | rna-NM_001180072.3_AKU4011 | cds-NP_010271.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:132876-134735:- | gene-YDL013W_BG1 | rna-NM_001180072.3_BG1 | cds-NP_010271.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:435720-437579:+ | gene-YDL013W_Bruggeman | rna-NM_001180072.3_Bruggeman | cds-NP_010271.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:428615-430474:+ | gene-YDL013W_CAT1 | rna-NM_001180072.3_CAT1 | cds-NP_010271.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:411564-413423:+ | gene-YDL013W_CBS1585 | rna-NM_001180072.3_CBS1585 | cds-NP_010271.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:429092-430951:+ | gene-YDL013W_CBS436 | rna-NM_001180072.3_CBS436 | cds-NP_010271.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:409279-411138:+ | gene-YDL013W_CBS6412 | rna-NM_001180072.3_CBS6412 | cds-NP_010271.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:431330-433189:+ | gene-YDL013W_CBS6413 | rna-NM_001180072.3_CBS6413 | cds-NP_010271.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:427929-429788:+ | gene-YDL013W_CENPK1137D | rna-NM_001180072.3_CENPK1137D | cds-NP_010271.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:423983-425842:+ | gene-YDL013W_EthanolRed | rna-NM_001180072.3_EthanolRed | cds-NP_010271.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:430175-432034:+ | gene-YDL013W_FaliES1 | rna-NM_001180072.3_FaliES1 | cds-NP_010271.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000370.1:44662-46521:+ | gene-YDL013W_JAY291 | rna-NM_001180072.3_JAY291 | cds-NP_010271.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:429610-431469:+ | gene-YDL013W_MUCL30387 | rna-NM_001180072.3_MUCL30387 | cds-NP_010271.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:420066-421925:+ | gene-YDL013W_MUCL30388 | rna-NM_001180072.3_MUCL30388 | cds-NP_010271.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:413238-415097:+ | gene-YDL013W_MUCL39482 | rna-NM_001180072.3_MUCL39482 | cds-NP_010271.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:335118-336977:+ | gene-YDL013W_MUCL42920 | rna-NM_001180072.3_MUCL42920 | cds-NP_010271.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:428990-430849:+ | gene-YDL013W_NCIM3186 | rna-NM_001180072.3_NCIM3186 | cds-NP_010271.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:412660-414519:+ | gene-YDL013W_NCYC1407 | rna-NM_001180072.3_NCYC1407 | cds-NP_010271.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:420143-422002:+ | gene-YDL013W_PE2H3 | rna-NM_001180072.3_PE2H3 | cds-NP_010271.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:419501-421360:+ | gene-YDL013W_PE2H4 | rna-NM_001180072.3_PE2H4 | cds-NP_010271.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:429067-430926:+ | gene-YDL013W_S288C | rna-NM_001180072.3_S288C | cds-NP_010271.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:4040-5899:- | gene-YDL013W_SA1 | rna-NM_001180072.3_SA1 | cds-NP_010271.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:429635-431494:+ | gene-YDL013W_ThermosaccDry | rna-NM_001180072.3_ThermosaccDry | cds-NP_010271.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:432648-434507:+ | gene-YDL013W_VR1 | rna-NM_001180072.3_VR1 | cds-NP_010271.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:427533-429392:+ | gene-YDL013W_ZTW1 | rna-NM_001180072.3_ZTW1 | cds-NP_010271.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:431703-433550:+ | gene-YDL013W_Sparadoxus | rna-NM_001180072.3_Sparadoxus | cds-NP_010271.3_Sparadoxus | 90.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |