Gene name: SLT2
Reference locus (S288C): YHR030C
Gene biotype: protein_coding
Description: Mitogen-activated protein kinase SLT2/MPK1; Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway
Top 10 interactors (score): RLM1 (0.999); MSG5 (0.998); MKK1 (0.998); SWI4 (0.997); SDP1 (0.997); MKK2 (0.996); SKO1 (0.996); PTP2 (0.99); STE7 (0.99); GCN4 (0.989); RHO1 (0.987); SWI6 (0.986); SPA2 (0.985); PTP3 (0.985); PBS2 (0.983); CLA4 (0.977); STE20 (0.969); BCK1 (0.969); GPA1 (0.959); ACA1 (0.957)
Homologues (species, bitscore): MAPK7 (Homo sapiens, 350.9); Mapk7 (Mus musculus, 350.9); mapk7 (Danio rerio, 354.8); mapk7 (Xenopus tropicalis, 360.1); rl (Drosophila melanogaster, 318.2); mpk-1 (Caenorhabditis elegans, 316.2); MPK4 (Arabidopsis thaliana, 335.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:157095-158573:- | gene-YHR030C_AKU4011 | rna-NM_001179160.1_AKU4011 | cds-NP_011895.1_AKU4011 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:77365-78819:- | gene-YHR030C_BG1 | rna-NM_001179160.1_BG1 | cds-NP_011895.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:164605-166053:- | gene-YHR030C_Bruggeman | rna-NM_001179160.1_Bruggeman | cds-NP_011895.1_Bruggeman | 99.2 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:158984-160438:- | gene-YHR030C_CAT1 | rna-NM_001179160.1_CAT1 | cds-NP_011895.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:157448-158920:- | gene-YHR030C_CBS1585 | rna-NM_001179160.1_CBS1585 | cds-NP_011895.1_CBS1585 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:151760-153220:- | gene-YHR030C_CBS436 | rna-NM_001179160.1_CBS436 | cds-NP_011895.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:156732-158219:- | gene-YHR030C_CBS6412 | rna-NM_001179160.1_CBS6412 | cds-NP_011895.1_CBS6412 | 97.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:157251-158735:- | gene-YHR030C_CBS6413 | rna-NM_001179160.1_CBS6413 | cds-NP_011895.1_CBS6413 | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:162159-163613:- | gene-YHR030C_CENPK1137D | rna-NM_001179160.1_CENPK1137D | cds-NP_011895.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:156626-158116:- | gene-YHR030C_EthanolRed | rna-NM_001179160.1_EthanolRed | cds-NP_011895.1_EthanolRed | 97.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:157605-159095:- | gene-YHR030C_FaliES1 | rna-NM_001179160.1_FaliES1 | cds-NP_011895.1_FaliES1 | 97.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000273.1:22550-24004:+ | gene-YHR030C_JAY291 | rna-NM_001179160.1_JAY291 | cds-NP_011895.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:163672-165126:- | gene-YHR030C_MUCL30387 | rna-NM_001179160.1_MUCL30387 | cds-NP_011895.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:164144-165592:- | gene-YHR030C_MUCL30388 | rna-NM_001179160.1_MUCL30388 | cds-NP_011895.1_MUCL30388 | 99.3 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:156507-157991:- | gene-YHR030C_MUCL39482 | rna-NM_001179160.1_MUCL39482 | cds-NP_011895.1_MUCL39482 | 97.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:163217-164683:- | gene-YHR030C_MUCL42920 | rna-NM_001179160.1_MUCL42920 | cds-NP_011895.1_MUCL42920 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:168772-170226:- | gene-YHR030C_NCIM3186 | rna-NM_001179160.1_NCIM3186 | cds-NP_011895.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:156365-157837:- | gene-YHR030C_NCYC1407 | rna-NM_001179160.1_NCYC1407 | cds-NP_011895.1_NCYC1407 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:158762-160210:- | gene-YHR030C_PE2H3 | rna-NM_001179160.1_PE2H3 | cds-NP_011895.1_PE2H3 | 99.2 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:166203-167651:- | gene-YHR030C_PE2H4 | rna-NM_001179160.1_PE2H4 | cds-NP_011895.1_PE2H4 | 99.2 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:168890-170344:- | gene-YHR030C_S288C | rna-NM_001179160.1_S288C | cds-NP_011895.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000106.1:22432-23880:- | gene-YHR030C_SA1 | rna-NM_001179160.1_SA1 | cds-NP_011895.1_SA1 | 99.2 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:158694-160184:- | gene-YHR030C_ThermosaccDry | rna-NM_001179160.1_ThermosaccDry | cds-NP_011895.1_ThermosaccDry | 97.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:165234-166706:- | gene-YHR030C_VR1 | rna-NM_001179160.1_VR1 | cds-NP_011895.1_VR1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:150283-151743:- | gene-YHR030C_ZTW1 | rna-NM_001179160.1_ZTW1 | cds-NP_011895.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:156407-157837:- | gene-YHR030C_Sparadoxus | rna-NM_001179160.1_Sparadoxus | cds-NP_011895.1_Sparadoxus | 90.5 | 98.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |