SLM3 (YDL033C)


Gene profile

Gene name: SLM3
Reference locus (S288C): YDL033C
Gene biotype: protein_coding

Description: TRNA-5-taurinomethyluridine 2-sulfurtransferase; tRNA-specific 2-thiouridylase; responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human homolog TRMU is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF), and can complement yeast null mutant

Top 10 interactors (score): MTO1 (0.999); MSS1 (0.992); TUM1 (0.97); NCS6 (0.873); NFS1 (0.866); GRC3 (0.808); ISU1 (0.77); COB (0.756); AI5_ALPHA (0.755); PUS1 (0.747); MOD5 (0.724); KRE29 (0.72); COF1 (0.719); MSS18 (0.716); ATP6 (0.716); LTP1 (0.713); KAE1 (0.699); RIB2 (0.697); PFK1 (0.69); AIM25 (0.685)

Homologues (species, bitscore): TRMU (Homo sapiens, 172.6); Trmu (Mus musculus, 172.6); trmu (Danio rerio, 176.4); trmu (Xenopus tropicalis, 189.1); CG3021 (Drosophila melanogaster, 189.9); B0035.16 (Caenorhabditis elegans, 160.2); AT1G51310 (Arabidopsis thaliana, 157.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:378736-379989:- gene-YDL033C_AKU4011 rna-NM_001180092.1_AKU4011 cds-NP_010251.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:169881-171134:+ gene-YDL033C_BG1 rna-NM_001180092.1_BG1 cds-NP_010251.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:397401-398654:- gene-YDL033C_Bruggeman rna-NM_001180092.1_Bruggeman cds-NP_010251.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:391943-393196:- gene-YDL033C_CAT1 rna-NM_001180092.1_CAT1 cds-NP_010251.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:375151-376404:- gene-YDL033C_CBS1585 rna-NM_001180092.1_CBS1585 cds-NP_010251.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:392682-393935:- gene-YDL033C_CBS436 rna-NM_001180092.1_CBS436 cds-NP_010251.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:372941-374194:- gene-YDL033C_CBS6412 rna-NM_001180092.1_CBS6412 cds-NP_010251.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:394913-396166:- gene-YDL033C_CBS6413 rna-NM_001180092.1_CBS6413 cds-NP_010251.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:391518-392771:- gene-YDL033C_CENPK1137D rna-NM_001180092.1_CENPK1137D cds-NP_010251.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:387566-388819:- gene-YDL033C_EthanolRed rna-NM_001180092.1_EthanolRed cds-NP_010251.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:393758-395011:- gene-YDL033C_FaliES1 rna-NM_001180092.1_FaliES1 cds-NP_010251.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000370.1:8301-9554:- gene-YDL033C_JAY291 rna-NM_001180092.1_JAY291 cds-NP_010251.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:393132-394385:- gene-YDL033C_MUCL30387 rna-NM_001180092.1_MUCL30387 cds-NP_010251.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:383646-384899:- gene-YDL033C_MUCL30388 rna-NM_001180092.1_MUCL30388 cds-NP_010251.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:376329-377582:- gene-YDL033C_MUCL39482 rna-NM_001180092.1_MUCL39482 cds-NP_010251.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:298692-299945:- gene-YDL033C_MUCL42920 rna-NM_001180092.1_MUCL42920 cds-NP_010251.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:392582-393835:- gene-YDL033C_NCIM3186 rna-NM_001180092.1_NCIM3186 cds-NP_010251.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:376244-377497:- gene-YDL033C_NCYC1407 rna-NM_001180092.1_NCYC1407 cds-NP_010251.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:383782-385035:- gene-YDL033C_PE2H3 rna-NM_001180092.1_PE2H3 cds-NP_010251.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:383140-384393:- gene-YDL033C_PE2H4 rna-NM_001180092.1_PE2H4 cds-NP_010251.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:392659-393912:- gene-YDL033C_S288C rna-NM_001180092.1_S288C cds-NP_010251.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:41026-42279:+ gene-YDL033C_SA1 rna-NM_001180092.1_SA1 cds-NP_010251.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:393216-394469:- gene-YDL033C_ThermosaccDry rna-NM_001180092.1_ThermosaccDry cds-NP_010251.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:396276-397529:- gene-YDL033C_VR1 rna-NM_001180092.1_VR1 cds-NP_010251.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:391118-392371:- gene-YDL033C_ZTW1 rna-NM_001180092.1_ZTW1 cds-NP_010251.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:395340-396593:- gene-YDL033C_Sparadoxus rna-NM_001180092.1_Sparadoxus cds-NP_010251.1_Sparadoxus 88.1 100.0 Verified 1 1 0 False False False True False

Additional files