Gene name: SLM1
Reference locus (S288C): YIL105C
Gene biotype: protein_coding
Description: Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1; Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; TORC2 complex substrate and effector; protein abundance increases in response to DNA replication stress; SLM1 has a paralog, SLM2, that arose from the whole genome duplication
Top 10 interactors (score): SLM2 (0.999); AVO2 (0.99); TOR2 (0.986); TSC11 (0.986); BIT61 (0.97); LST8 (0.963); AVO1 (0.956); BIT2 (0.938); PKH1 (0.874); TOR1 (0.865); PIL1 (0.853); PKH2 (0.838); MSS4 (0.836); CNA1 (0.818); SAC7 (0.799); YPK2 (0.796); ORM1 (0.793); YPK1 (0.785); NCE102 (0.778); RCN1 (0.76)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:169055-171109:- | gene-YIL105C_AKU4011 | rna-NM_001179453.1_AKU4011 | cds-NP_012161.1_AKU4011 | 98.9 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:31990-34050:- | gene-YIL105C_BG1 | rna-NM_001179453.1_BG1 | cds-NP_012161.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:173693-175744:- | gene-YIL105C_Bruggeman | rna-NM_001179453.1_Bruggeman | cds-NP_012161.1_Bruggeman | 98.7 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:165735-167795:- | gene-YIL105C_CAT1 | rna-NM_001179453.1_CAT1 | cds-NP_012161.1_CAT1 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:169311-171365:- | gene-YIL105C_CBS1585 | rna-NM_001179453.1_CBS1585 | cds-NP_012161.1_CBS1585 | 98.9 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:160228-162288:- | gene-YIL105C_CBS436 | rna-NM_001179453.1_CBS436 | cds-NP_012161.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:166691-168745:- | gene-YIL105C_CBS6412 | rna-NM_001179453.1_CBS6412 | cds-NP_012161.1_CBS6412 | 98.9 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:160344-162398:- | gene-YIL105C_CBS6413 | rna-NM_001179453.1_CBS6413 | cds-NP_012161.1_CBS6413 | 98.9 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:159294-161354:- | gene-YIL105C_CENPK1137D | rna-NM_001179453.1_CENPK1137D | cds-NP_012161.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:154280-156331:- | gene-YIL105C_EthanolRed | rna-NM_001179453.1_EthanolRed | cds-NP_012161.1_EthanolRed | 98.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:170275-172326:- | gene-YIL105C_FaliES1 | rna-NM_001179453.1_FaliES1 | cds-NP_012161.1_FaliES1 | 98.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000025.1:56210-58270:+ | gene-YIL105C_JAY291 | rna-NM_001179453.1_JAY291 | cds-NP_012161.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:170529-172580:- | gene-YIL105C_MUCL30387 | rna-NM_001179453.1_MUCL30387 | cds-NP_012161.1_MUCL30387 | 98.7 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:169271-171322:- | gene-YIL105C_MUCL30388 | rna-NM_001179453.1_MUCL30388 | cds-NP_012161.1_MUCL30388 | 98.7 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:170157-172211:- | gene-YIL105C_MUCL39482 | rna-NM_001179453.1_MUCL39482 | cds-NP_012161.1_MUCL39482 | 98.9 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:173413-175464:- | gene-YIL105C_MUCL42920 | rna-NM_001179453.1_MUCL42920 | cds-NP_012161.1_MUCL42920 | 98.7 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:167581-169641:- | gene-YIL105C_NCIM3186 | rna-NM_001179453.1_NCIM3186 | cds-NP_012161.1_NCIM3186 | 97.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:174200-176254:- | gene-YIL105C_NCYC1407 | rna-NM_001179453.1_NCYC1407 | cds-NP_012161.1_NCYC1407 | 98.9 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:168689-170749:- | gene-YIL105C_PE2H3 | rna-NM_001179453.1_PE2H3 | cds-NP_012161.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:162736-164787:- | gene-YIL105C_PE2H4 | rna-NM_001179453.1_PE2H4 | cds-NP_012161.1_PE2H4 | 98.7 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:167581-169641:- | gene-YIL105C_S288C | rna-NM_001179453.1_S288C | cds-NP_012161.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000058.1:13738-15789:+ | gene-YIL105C_SA1 | rna-NM_001179453.1_SA1 | cds-NP_012161.1_SA1 | 98.8 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:168944-170995:- | gene-YIL105C_ThermosaccDry | rna-NM_001179453.1_ThermosaccDry | cds-NP_012161.1_ThermosaccDry | 98.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:165840-167900:- | gene-YIL105C_VR1 | rna-NM_001179453.1_VR1 | cds-NP_012161.1_VR1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:143874-145929:- | gene-YIL105C_ZTW1 | rna-NM_001179453.1_ZTW1 | cds-NP_012161.1_ZTW1 | 98.8 | 99.7 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:161706-163763:- | gene-YIL105C_Sparadoxus | rna-NM_001179453.1_Sparadoxus | cds-NP_012161.1_Sparadoxus | 91.9 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |