SLK19 (YOR195W)


Gene profile

Gene name: SLK19
Reference locus (S288C): YOR195W
Gene biotype: protein_coding

Description: Kinetochore-associated protein; required for chromosome segregation and kinetochore clustering; required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate

Top 10 interactors (score): ESP1 (0.998); CDC55 (0.971); CDC14 (0.97); CIN8 (0.963); SPO12 (0.944); PDS1 (0.944); LTE1 (0.939); MAD2 (0.925); CDC5 (0.918); KAR3 (0.913); BIM1 (0.899); CLB2 (0.888); NET1 (0.868); STU2 (0.86); CDC15 (0.839); TPD3 (0.836); MAD1 (0.832); KIP3 (0.828); PPH21 (0.814); PPH22 (0.808)

Homologues (species, bitscore): LAMA2 (Homo sapiens, 53.1); lama5 (Danio rerio, 55.8); lama5 (Xenopus tropicalis, 60.5); dyf-14 (Caenorhabditis elegans, 55.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:703651-706116:+ gene-YOR195W_AKU4011 rna-NM_001183614.3_AKU4011 cds-NP_014838.3_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:105691-108156:+ gene-YOR195W_BG1 rna-NM_001183614.3_BG1 cds-NP_014838.3_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:688482-690947:+ gene-YOR195W_Bruggeman rna-NM_001183614.3_Bruggeman cds-NP_014838.3_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:689765-692230:+ gene-YOR195W_CAT1 rna-NM_001183614.3_CAT1 cds-NP_014838.3_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:686638-689103:+ gene-YOR195W_CBS1585 rna-NM_001183614.3_CBS1585 cds-NP_014838.3_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:685328-687793:+ gene-YOR195W_CBS436 rna-NM_001183614.3_CBS436 cds-NP_014838.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:683756-686221:+ gene-YOR195W_CBS6412 rna-NM_001183614.3_CBS6412 cds-NP_014838.3_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:692395-694860:+ gene-YOR195W_CBS6413 rna-NM_001183614.3_CBS6413 cds-NP_014838.3_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:712621-715086:+ gene-YOR195W_CENPK1137D rna-NM_001183614.3_CENPK1137D cds-NP_014838.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:679781-682246:+ gene-YOR195W_EthanolRed rna-NM_001183614.3_EthanolRed cds-NP_014838.3_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:685178-687643:+ gene-YOR195W_FaliES1 rna-NM_001183614.3_FaliES1 cds-NP_014838.3_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:139104-141569:- gene-YOR195W_JAY291 rna-NM_001183614.3_JAY291 cds-NP_014838.3_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:692448-694913:+ gene-YOR195W_MUCL30387 rna-NM_001183614.3_MUCL30387 cds-NP_014838.3_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:699866-702331:+ gene-YOR195W_MUCL30388 rna-NM_001183614.3_MUCL30388 cds-NP_014838.3_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:693967-696432:+ gene-YOR195W_MUCL39482 rna-NM_001183614.3_MUCL39482 cds-NP_014838.3_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:703551-706016:+ gene-YOR195W_MUCL42920 rna-NM_001183614.3_MUCL42920 cds-NP_014838.3_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:712755-715220:+ gene-YOR195W_NCIM3186 rna-NM_001183614.3_NCIM3186 cds-NP_014838.3_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:694065-696530:+ gene-YOR195W_NCYC1407 rna-NM_001183614.3_NCYC1407 cds-NP_014838.3_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:693464-695929:+ gene-YOR195W_PE2H3 rna-NM_001183614.3_PE2H3 cds-NP_014838.3_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:703841-706306:+ gene-YOR195W_PE2H4 rna-NM_001183614.3_PE2H4 cds-NP_014838.3_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:712866-715331:+ gene-YOR195W_S288C rna-NM_001183614.3_S288C cds-NP_014838.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:122871-125336:+ gene-YOR195W_SA1 rna-NM_001183614.3_SA1 cds-NP_014838.3_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:684363-686828:+ gene-YOR195W_ThermosaccDry rna-NM_001183614.3_ThermosaccDry cds-NP_014838.3_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:747904-750369:+ gene-YOR195W_VR1 rna-NM_001183614.3_VR1 cds-NP_014838.3_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:417279-419743:+ gene-YOR195W_ZTW1 rna-NM_001183614.3_ZTW1 cds-NP_014838.3_ZTW1 99.3 99.9 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:690276-692741:+ gene-YOR195W_Sparadoxus rna-NM_001183614.3_Sparadoxus cds-NP_014838.3_Sparadoxus 87.1 99.9 Verified 1 1 1 False True False False False

Additional files