SLD5 (YDR489W)


Gene profile

Gene name: SLD5
Reference locus (S288C): YDR489W
Gene biotype: protein_coding

Description: Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p); complex is localized to DNA replication origins and implicated in assembly of the DNA replication machinery; Belongs to the GINS4/SLD5 family

Top 10 interactors (score): CSM3 (0.999); MCM4 (0.999); MCM10 (0.999); CTF4 (0.999); PSF3 (0.999); MCM5 (0.999); PSF1 (0.999); PSF2 (0.999); MCM3 (0.999); MCM6 (0.999); MCM2 (0.999); CDC45 (0.999); MCM7 (0.999); TOF1 (0.998); DPB11 (0.997); DPB2 (0.996); POL2 (0.996); CDC6 (0.995); POB3 (0.994); POL1 (0.994)

Homologues (species, bitscore): GINS4 (Homo sapiens, 59.3); Gins4 (Mus musculus, 63.9); gins4 (Danio rerio, 64.7); gins4 (Xenopus tropicalis, 59.7); Sld5 (Drosophila melanogaster, 65.9); sld-5 (Caenorhabditis elegans, 63.2); SLD5 (Arabidopsis thaliana, 58.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1370939-1371823:+ gene-YDR489W_AKU4011 rna-NM_001180797.3_AKU4011 cds-NP_010777.3_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:12541-13425:+ gene-YDR489W_BG1 rna-NM_001180797.3_BG1 cds-NP_010777.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1402343-1403227:+ gene-YDR489W_Bruggeman rna-NM_001180797.3_Bruggeman cds-NP_010777.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1379487-1380371:+ gene-YDR489W_CAT1 rna-NM_001180797.3_CAT1 cds-NP_010777.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1365238-1366122:+ gene-YDR489W_CBS1585 rna-NM_001180797.3_CBS1585 cds-NP_010777.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1384588-1385472:+ gene-YDR489W_CBS436 rna-NM_001180797.3_CBS436 cds-NP_010777.3_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1360862-1361746:+ gene-YDR489W_CBS6412 rna-NM_001180797.3_CBS6412 cds-NP_010777.3_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1383873-1384757:+ gene-YDR489W_CBS6413 rna-NM_001180797.3_CBS6413 cds-NP_010777.3_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1429708-1430592:+ gene-YDR489W_CENPK1137D rna-NM_001180797.3_CENPK1137D cds-NP_010777.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1374278-1375162:+ gene-YDR489W_EthanolRed rna-NM_001180797.3_EthanolRed cds-NP_010777.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1377831-1378715:+ gene-YDR489W_FaliES1 rna-NM_001180797.3_FaliES1 cds-NP_010777.3_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:76076-76960:+ gene-YDR489W_JAY291 rna-NM_001180797.3_JAY291 cds-NP_010777.3_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1384829-1385713:+ gene-YDR489W_MUCL30387 rna-NM_001180797.3_MUCL30387 cds-NP_010777.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1366861-1367745:+ gene-YDR489W_MUCL30388 rna-NM_001180797.3_MUCL30388 cds-NP_010777.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1356723-1357607:+ gene-YDR489W_MUCL39482 rna-NM_001180797.3_MUCL39482 cds-NP_010777.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1299504-1300388:+ gene-YDR489W_MUCL42920 rna-NM_001180797.3_MUCL42920 cds-NP_010777.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1430935-1431819:+ gene-YDR489W_NCIM3186 rna-NM_001180797.3_NCIM3186 cds-NP_010777.3_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1370492-1371376:+ gene-YDR489W_NCYC1407 rna-NM_001180797.3_NCYC1407 cds-NP_010777.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1381343-1382227:+ gene-YDR489W_PE2H3 rna-NM_001180797.3_PE2H3 cds-NP_010777.3_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1386917-1387801:+ gene-YDR489W_PE2H4 rna-NM_001180797.3_PE2H4 cds-NP_010777.3_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1431012-1431896:+ gene-YDR489W_S288C rna-NM_001180797.3_S288C cds-NP_010777.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:185253-186137:- gene-YDR489W_SA1 rna-NM_001180797.3_SA1 cds-NP_010777.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1382053-1382937:+ gene-YDR489W_ThermosaccDry rna-NM_001180797.3_ThermosaccDry cds-NP_010777.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1397788-1398672:+ gene-YDR489W_VR1 rna-NM_001180797.3_VR1 cds-NP_010777.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:424720-425604:+ gene-YDR489W_ZTW1 rna-NM_001180797.3_ZTW1 cds-NP_010777.3_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1384858-1385742:+ gene-YDR489W_Sparadoxus rna-NM_001180797.3_Sparadoxus cds-NP_010777.3_Sparadoxus 90.5 100.0 Verified 1 1 1 False True False False False

Additional files