SLA2 (YNL243W)


Gene profile

Gene name: SLA2
Reference locus (S288C): YNL243W
Gene biotype: protein_coding

Description: Adaptor protein that links actin to clathrin and endocytosis; involved in membrane cytoskeleton assembly and cell polarization; present in the actin cortical patch of the emerging bud tip; dimer in vivo; Belongs to the SLA2 family

Top 10 interactors (score): ABP1 (0.999); ARP2 (0.999); CLC1 (0.999); PAN1 (0.998); END3 (0.998); ENT1 (0.997); ACT1 (0.996); CHC1 (0.995); SLA1 (0.995); EDE1 (0.994); LAS17 (0.991); VRP1 (0.99); YAP1801 (0.99); YAP1802 (0.986); PRK1 (0.98); SAC6 (0.977); RVS167 (0.977); VPS28 (0.973); ENT2 (0.97); VPS1 (0.97)

Homologues (species, bitscore): HIP1R (Homo sapiens, 188.0); Hip1r (Mus musculus, 180.6); hip1 (Danio rerio, 195.3); hip1r (Xenopus tropicalis, 203.0); Hip1 (Drosophila melanogaster, 127.5); hipr-1 (Caenorhabditis elegans, 172.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:181836-184742:+ gene-YNL243W_AKU4011 rna-NM_001183081.2_AKU4011 cds-NP_014156.2_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:85777-88683:+ gene-YNL243W_BG1 rna-NM_001183081.2_BG1 cds-NP_014156.2_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:191640-194546:+ gene-YNL243W_Bruggeman rna-NM_001183081.2_Bruggeman cds-NP_014156.2_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:198936-201842:+ gene-YNL243W_CAT1 rna-NM_001183081.2_CAT1 cds-NP_014156.2_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:182235-185141:+ gene-YNL243W_CBS1585 rna-NM_001183081.2_CBS1585 cds-NP_014156.2_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:177320-180226:+ gene-YNL243W_CBS436 rna-NM_001183081.2_CBS436 cds-NP_014156.2_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:178272-181178:+ gene-YNL243W_CBS6412 rna-NM_001183081.2_CBS6412 cds-NP_014156.2_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:178915-181821:+ gene-YNL243W_CBS6413 rna-NM_001183081.2_CBS6413 cds-NP_014156.2_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:181862-184768:+ gene-YNL243W_CENPK1137D rna-NM_001183081.2_CENPK1137D cds-NP_014156.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:179493-182399:+ gene-YNL243W_EthanolRed rna-NM_001183081.2_EthanolRed cds-NP_014156.2_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:174228-177134:+ gene-YNL243W_FaliES1 rna-NM_001183081.2_FaliES1 cds-NP_014156.2_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:85369-88275:+ gene-YNL243W_JAY291 rna-NM_001183081.2_JAY291 cds-NP_014156.2_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:187424-190330:+ gene-YNL243W_MUCL30387 rna-NM_001183081.2_MUCL30387 cds-NP_014156.2_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:186007-188913:+ gene-YNL243W_MUCL30388 rna-NM_001183081.2_MUCL30388 cds-NP_014156.2_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:179725-182631:+ gene-YNL243W_MUCL39482 rna-NM_001183081.2_MUCL39482 cds-NP_014156.2_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:181981-184887:+ gene-YNL243W_MUCL42920 rna-NM_001183081.2_MUCL42920 cds-NP_014156.2_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:188020-190926:+ gene-YNL243W_NCIM3186 rna-NM_001183081.2_NCIM3186 cds-NP_014156.2_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:181813-184719:+ gene-YNL243W_NCYC1407 rna-NM_001183081.2_NCYC1407 cds-NP_014156.2_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:178713-181619:+ gene-YNL243W_PE2H3 rna-NM_001183081.2_PE2H3 cds-NP_014156.2_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:178101-181007:+ gene-YNL243W_PE2H4 rna-NM_001183081.2_PE2H4 cds-NP_014156.2_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:188051-190957:+ gene-YNL243W_S288C rna-NM_001183081.2_S288C cds-NP_014156.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000040.1:61339-64245:- gene-YNL243W_SA1 rna-NM_001183081.2_SA1 cds-NP_014156.2_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:175084-177990:+ gene-YNL243W_ThermosaccDry rna-NM_001183081.2_ThermosaccDry cds-NP_014156.2_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:193970-196876:+ gene-YNL243W_VR1 rna-NM_001183081.2_VR1 cds-NP_014156.2_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:85405-88311:+ gene-YNL243W_ZTW1 rna-NM_001183081.2_ZTW1 cds-NP_014156.2_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:185345-188251:+ gene-YNL243W_Sparadoxus rna-NM_001183081.2_Sparadoxus cds-NP_014156.2_Sparadoxus 91.5 100.0 Verified 1 1 1 False True False False False

Additional files