SLA1 (YBL007C)


Gene profile

Gene name: SLA1
Reference locus (S288C): YBL007C
Gene biotype: protein_coding

Description: Actin cytoskeleton-regulatory complex protein SLA1; Cytoskeletal protein binding protein; required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains; Belongs to the SLA1 family

Top 10 interactors (score): LAS17 (0.997); END3 (0.995); SLA2 (0.995); LSB3 (0.991); ABP1 (0.99); YSC84 (0.988); BSP1 (0.977); RVS167 (0.977); PRK1 (0.972); VRP1 (0.966); EDE1 (0.96); UBI4 (0.951); ARK1 (0.947); LSB5 (0.944); BZZ1 (0.944); RVS161 (0.939); INP52 (0.938); SUP35 (0.923); ACT1 (0.92); SAC6 (0.916)

Homologues (species, bitscore): SH3RF3 (Homo sapiens, 53.5); Itsn1 (Mus musculus, 51.6); pacsin1b (Danio rerio, 52.4); stam2 (Xenopus tropicalis, 53.5); dock (Drosophila melanogaster, 52.4); nck-1 (Caenorhabditis elegans, 54.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:206737-210426:- gene-YBL007C_AKU4011 rna-NM_001178247.1_AKU4011 cds-NP_009546.1_AKU4011 98.5 98.7 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:197058-200792:- gene-YBL007C_BG1 rna-NM_001178247.1_BG1 cds-NP_009546.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:207395-211129:- gene-YBL007C_Bruggeman rna-NM_001178247.1_Bruggeman cds-NP_009546.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:209922-213662:- gene-YBL007C_CAT1 rna-NM_001178247.1_CAT1 cds-NP_009546.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:199025-202714:- gene-YBL007C_CBS1585 rna-NM_001178247.1_CBS1585 cds-NP_009546.1_CBS1585 98.5 98.7 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:207230-210964:- gene-YBL007C_CBS436 rna-NM_001178247.1_CBS436 cds-NP_009546.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:297525-301214:- gene-YBL007C_CBS6412 rna-NM_001178247.1_CBS6412 cds-NP_009546.1_CBS6412 98.5 98.7 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:204345-208079:- gene-YBL007C_CBS6413 rna-NM_001178247.1_CBS6413 cds-NP_009546.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:206398-210132:- gene-YBL007C_CENPK1137D rna-NM_001178247.1_CENPK1137D cds-NP_009546.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:333967-337671:- gene-YBL007C_EthanolRed rna-NM_001178247.1_EthanolRed cds-NP_009546.1_EthanolRed 98.2 98.7 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:221568-225272:- gene-YBL007C_FaliES1 rna-NM_001178247.1_FaliES1 cds-NP_009546.1_FaliES1 98.2 98.7 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000048.1:71819-75553:+ gene-YBL007C_JAY291 rna-NM_001178247.1_JAY291 cds-NP_009546.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:207993-211727:- gene-YBL007C_MUCL30387 rna-NM_001178247.1_MUCL30387 cds-NP_009546.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:207978-211667:- gene-YBL007C_MUCL30388 rna-NM_001178247.1_MUCL30388 cds-NP_009546.1_MUCL30388 98.3 98.7 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:198961-202695:- gene-YBL007C_MUCL39482 rna-NM_001178247.1_MUCL39482 cds-NP_009546.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:206402-210136:- gene-YBL007C_MUCL42920 rna-NM_001178247.1_MUCL42920 cds-NP_009546.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:212429-216163:- gene-YBL007C_NCIM3186 rna-NM_001178247.1_NCIM3186 cds-NP_009546.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:200136-203870:- gene-YBL007C_NCYC1407 rna-NM_001178247.1_NCYC1407 cds-NP_009546.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:212305-216039:- gene-YBL007C_PE2H3 rna-NM_001178247.1_PE2H3 cds-NP_009546.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:209949-213689:- gene-YBL007C_PE2H4 rna-NM_001178247.1_PE2H4 cds-NP_009546.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:212632-216366:- gene-YBL007C_S288C rna-NM_001178247.1_S288C cds-NP_009546.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000037.1:80491-84231:+ gene-YBL007C_SA1 rna-NM_001178247.1_SA1 cds-NP_009546.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:221523-225227:- gene-YBL007C_ThermosaccDry rna-NM_001178247.1_ThermosaccDry cds-NP_009546.1_ThermosaccDry 98.2 98.7 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:203645-207379:- gene-YBL007C_VR1 rna-NM_001178247.1_VR1 cds-NP_009546.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:197727-201461:- gene-YBL007C_ZTW1 rna-NM_001178247.1_ZTW1 cds-NP_009546.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:233300-237025:- gene-YBL007C_Sparadoxus rna-NM_001178247.1_Sparadoxus cds-NP_009546.1_Sparadoxus 87.8 97.8 Verified 1 1 1 False True False False False

Additional files