SKS1 (YPL026C)


Gene profile

Gene name: SKS1
Reference locus (S288C): YPL026C
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase SKS1; Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication

Top 10 interactors (score): GIS4 (0.813); ASG1 (0.745); SNF3 (0.743); MTC1 (0.698); CRP1 (0.682); YKR075C (0.673); FYV8 (0.613); EUG1 (0.611); GRR1 (0.598); ACC1 (0.598); ADH3 (0.593); HYM1 (0.589); TDA1 (0.586); YMR196W (0.574); VID27 (0.566); SNF4 (0.563); RAS2 (0.546); PRR1 (0.539); CDC37 (0.535); RGT1 (0.531)

Homologues (species, bitscore): PRKAA2 (Homo sapiens, 89.7); Prkaa2 (Mus musculus, 89.0); nek2 (Danio rerio, 85.1); prkaa2 (Xenopus tropicalis, 88.2); Sik3 (Drosophila melanogaster, 88.6); ZK524.4 (Caenorhabditis elegans, 90.1); SIP4 (Arabidopsis thaliana, 100.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:472167-473675:- gene-YPL026C_AKU4011 rna-NM_001183840.1_AKU4011 cds-NP_015299.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:423705-425198:+ gene-YPL026C_BG1 rna-NM_001183840.1_BG1 cds-NP_015299.1_BG1 98.0 99.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:549127-550626:- gene-YPL026C_Bruggeman rna-NM_001183840.1_Bruggeman cds-NP_015299.1_Bruggeman 98.9 99.4 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:588823-590316:- gene-YPL026C_CAT1 rna-NM_001183840.1_CAT1 cds-NP_015299.1_CAT1 98.1 99.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:476237-477745:- gene-YPL026C_CBS1585 rna-NM_001183840.1_CBS1585 cds-NP_015299.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:490390-491883:- gene-YPL026C_CBS436 rna-NM_001183840.1_CBS436 cds-NP_015299.1_CBS436 98.3 99.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:480429-481937:- gene-YPL026C_CBS6412 rna-NM_001183840.1_CBS6412 cds-NP_015299.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:472789-474297:- gene-YPL026C_CBS6413 rna-NM_001183840.1_CBS6413 cds-NP_015299.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:500643-502151:- gene-YPL026C_CENPK1137D rna-NM_001183840.1_CENPK1137D cds-NP_015299.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:470527-472035:- gene-YPL026C_EthanolRed rna-NM_001183840.1_EthanolRed cds-NP_015299.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:478357-479865:- gene-YPL026C_FaliES1 rna-NM_001183840.1_FaliES1 cds-NP_015299.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:86979-88472:- gene-YPL026C_JAY291 rna-NM_001183840.1_JAY291 cds-NP_015299.1_JAY291 98.0 99.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:490076-491575:- gene-YPL026C_MUCL30387 rna-NM_001183840.1_MUCL30387 cds-NP_015299.1_MUCL30387 99.0 99.4 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:489184-490683:- gene-YPL026C_MUCL30388 rna-NM_001183840.1_MUCL30388 cds-NP_015299.1_MUCL30388 98.9 99.4 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:469553-471061:- gene-YPL026C_MUCL39482 rna-NM_001183840.1_MUCL39482 cds-NP_015299.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:528697-530196:- gene-YPL026C_MUCL42920 rna-NM_001183840.1_MUCL42920 cds-NP_015299.1_MUCL42920 99.0 99.4 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:500658-502166:- gene-YPL026C_NCIM3186 rna-NM_001183840.1_NCIM3186 cds-NP_015299.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:476831-478339:- gene-YPL026C_NCYC1407 rna-NM_001183840.1_NCYC1407 cds-NP_015299.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:483496-484989:- gene-YPL026C_PE2H3 rna-NM_001183840.1_PE2H3 cds-NP_015299.1_PE2H3 98.0 99.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:483111-484604:- gene-YPL026C_PE2H4 rna-NM_001183840.1_PE2H4 cds-NP_015299.1_PE2H4 98.0 99.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:500675-502183:- gene-YPL026C_S288C rna-NM_001183840.1_S288C cds-NP_015299.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000029.1:43548-45041:- gene-YPL026C_SA1 rna-NM_001183840.1_SA1 cds-NP_015299.1_SA1 98.0 99.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:478156-479664:- gene-YPL026C_ThermosaccDry rna-NM_001183840.1_ThermosaccDry cds-NP_015299.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:493070-494563:- gene-YPL026C_VR1 rna-NM_001183840.1_VR1 cds-NP_015299.1_VR1 98.0 99.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:477448-478956:- gene-YPL026C_ZTW1 rna-NM_001183840.1_ZTW1 cds-NP_015299.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:477428-478891:- gene-YPL026C_Sparadoxus rna-NM_001183840.1_Sparadoxus cds-NP_015299.1_Sparadoxus 88.5 97.0 Verified 1 1 1 False True False False False

Additional files