Gene name: SKP1
Reference locus (S288C): YDR328C
Gene biotype: protein_coding
Description: S-phase kinase-associated protein 1; Evolutionarily conserved kinetochore protein; part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): CDC4 (0.999); GRR1 (0.999); HRT1 (0.999); CTF13 (0.999); HRT3 (0.999); CBF2 (0.999); CDC53 (0.999); UFO1 (0.999); SGT1 (0.999); CEP3 (0.999); MET30 (0.999); CUL3 (0.999); CDC34 (0.999); CKS1 (0.998); RCY1 (0.998); RAV1 (0.995); RTT101 (0.995); RRT13 (0.993); RAV2 (0.993); UBC12 (0.991)
Homologues (species, bitscore): SKP1 (Homo sapiens, 168.7); Skp1a (Mus musculus, 168.7); skp1 (Danio rerio, 169.5); skp1 (Xenopus tropicalis, 168.7); SkpA (Drosophila melanogaster, 151.8); skr-1 (Caenorhabditis elegans, 155.2); ASK2 (Arabidopsis thaliana, 137.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1071475-1072059:- | gene-YDR328C_AKU4011 | rna-NM_001180636.3_AKU4011 | cds-NP_010615.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:59502-60086:+ | gene-YDR328C_BG1 | rna-NM_001180636.3_BG1 | cds-NP_010615.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1099018-1099602:- | gene-YDR328C_Bruggeman | rna-NM_001180636.3_Bruggeman | cds-NP_010615.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1085761-1086345:- | gene-YDR328C_CAT1 | rna-NM_001180636.3_CAT1 | cds-NP_010615.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1065919-1066503:- | gene-YDR328C_CBS1585 | rna-NM_001180636.3_CBS1585 | cds-NP_010615.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1084301-1084885:- | gene-YDR328C_CBS436 | rna-NM_001180636.3_CBS436 | cds-NP_010615.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1062607-1063191:- | gene-YDR328C_CBS6412 | rna-NM_001180636.3_CBS6412 | cds-NP_010615.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1083838-1084422:- | gene-YDR328C_CBS6413 | rna-NM_001180636.3_CBS6413 | cds-NP_010615.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1124072-1124656:- | gene-YDR328C_CENPK1137D | rna-NM_001180636.3_CENPK1137D | cds-NP_010615.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:247017-247601:- | gene-YDR328C_EthanolRed | rna-NM_001180636.3_EthanolRed | cds-NP_010615.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1078232-1078816:- | gene-YDR328C_FaliES1 | rna-NM_001180636.3_FaliES1 | cds-NP_010615.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000386.1:30740-31324:- | gene-YDR328C_JAY291 | rna-NM_001180636.3_JAY291 | cds-NP_010615.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1084262-1084846:- | gene-YDR328C_MUCL30387 | rna-NM_001180636.3_MUCL30387 | cds-NP_010615.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1073214-1073798:- | gene-YDR328C_MUCL30388 | rna-NM_001180636.3_MUCL30388 | cds-NP_010615.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1057726-1058310:- | gene-YDR328C_MUCL39482 | rna-NM_001180636.3_MUCL39482 | cds-NP_010615.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1004793-1005377:- | gene-YDR328C_MUCL42920 | rna-NM_001180636.3_MUCL42920 | cds-NP_010615.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1125357-1125941:- | gene-YDR328C_NCIM3186 | rna-NM_001180636.3_NCIM3186 | cds-NP_010615.3_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1071017-1071601:- | gene-YDR328C_NCYC1407 | rna-NM_001180636.3_NCYC1407 | cds-NP_010615.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1082018-1082602:- | gene-YDR328C_PE2H3 | rna-NM_001180636.3_PE2H3 | cds-NP_010615.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1087603-1088187:- | gene-YDR328C_PE2H4 | rna-NM_001180636.3_PE2H4 | cds-NP_010615.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1125434-1126018:- | gene-YDR328C_S288C | rna-NM_001180636.3_S288C | cds-NP_010615.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:96245-96829:- | gene-YDR328C_SA1 | rna-NM_001180636.3_SA1 | cds-NP_010615.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1082505-1083089:- | gene-YDR328C_ThermosaccDry | rna-NM_001180636.3_ThermosaccDry | cds-NP_010615.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1098418-1099002:- | gene-YDR328C_VR1 | rna-NM_001180636.3_VR1 | cds-NP_010615.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:126615-127199:- | gene-YDR328C_ZTW1 | rna-NM_001180636.3_ZTW1 | cds-NP_010615.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1077933-1078514:- | gene-YDR328C_Sparadoxus | rna-NM_001180636.3_Sparadoxus | cds-NP_010615.3_Sparadoxus | 92.4 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |