Gene name: SKN7
Reference locus (S288C): YHR206W
Gene biotype: protein_coding
Description: Transcription factor SKN7; Nuclear response regulator and transcription factor; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation; relocalizes to the cytosol in response to hypoxia; SKN7 has a paralog, HMS2, that arose from the whole genome duplication
Top 10 interactors (score): YPD1 (0.999); YAP1 (0.996); SSK1 (0.989); SMT3 (0.978); RIM11 (0.959); FUS3 (0.952); HOG1 (0.951); KSS1 (0.948); SSA1 (0.943); TOR2 (0.942); SSA3 (0.942); KOG1 (0.941); SSA2 (0.935); SSA4 (0.932); TEF1 (0.925); MBP1 (0.92); TRR1 (0.919); MSN2 (0.919); SKO1 (0.916); TRX1 (0.91)
Homologues (species, bitscore): HSF2 (Homo sapiens, 93.6); Hsf2 (Mus musculus, 93.6); hsf1 (Danio rerio, 92.0); hsf1 (Xenopus tropicalis, 93.2); Hsf (Drosophila melanogaster, 92.0); hsf-1 (Caenorhabditis elegans, 65.9); HSFA7A (Arabidopsis thaliana, 85.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:499788-501656:+ | gene-YHR206W_AKU4011 | rna-NM_001179337.3_AKU4011 | cds-NP_012076.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:16076-17944:- | gene-YHR206W_BG1 | rna-NM_001179337.3_BG1 | cds-NP_012076.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:507275-509143:+ | gene-YHR206W_Bruggeman | rna-NM_001179337.3_Bruggeman | cds-NP_012076.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:503830-505698:+ | gene-YHR206W_CAT1 | rna-NM_001179337.3_CAT1 | cds-NP_012076.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:499224-501080:+ | gene-YHR206W_CBS1585 | rna-NM_001179337.3_CBS1585 | cds-NP_012076.3_CBS1585 | 98.7 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:497331-499199:+ | gene-YHR206W_CBS436 | rna-NM_001179337.3_CBS436 | cds-NP_012076.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:499341-501197:+ | gene-YHR206W_CBS6412 | rna-NM_001179337.3_CBS6412 | cds-NP_012076.3_CBS6412 | 98.8 | 99.3 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:500596-502464:+ | gene-YHR206W_CBS6413 | rna-NM_001179337.3_CBS6413 | cds-NP_012076.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:505956-507824:+ | gene-YHR206W_CENPK1137D | rna-NM_001179337.3_CENPK1137D | cds-NP_012076.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:558343-560211:+ | gene-YHR206W_EthanolRed | rna-NM_001179337.3_EthanolRed | cds-NP_012076.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:500794-502662:+ | gene-YHR206W_FaliES1 | rna-NM_001179337.3_FaliES1 | cds-NP_012076.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000071.1:7555-9423:+ | gene-YHR206W_JAY291 | rna-NM_001179337.3_JAY291 | cds-NP_012076.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:508373-510241:+ | gene-YHR206W_MUCL30387 | rna-NM_001179337.3_MUCL30387 | cds-NP_012076.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:508031-509899:+ | gene-YHR206W_MUCL30388 | rna-NM_001179337.3_MUCL30388 | cds-NP_012076.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:499341-501197:+ | gene-YHR206W_MUCL39482 | rna-NM_001179337.3_MUCL39482 | cds-NP_012076.3_MUCL39482 | 98.7 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:514669-516537:+ | gene-YHR206W_MUCL42920 | rna-NM_001179337.3_MUCL42920 | cds-NP_012076.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:512614-514482:+ | gene-YHR206W_NCIM3186 | rna-NM_001179337.3_NCIM3186 | cds-NP_012076.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:501629-503497:+ | gene-YHR206W_NCYC1407 | rna-NM_001179337.3_NCYC1407 | cds-NP_012076.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:500804-502672:+ | gene-YHR206W_PE2H3 | rna-NM_001179337.3_PE2H3 | cds-NP_012076.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:508231-510099:+ | gene-YHR206W_PE2H4 | rna-NM_001179337.3_PE2H4 | cds-NP_012076.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:512732-514600:+ | gene-YHR206W_S288C | rna-NM_001179337.3_S288C | cds-NP_012076.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000112.1:7617-9485:+ | gene-YHR206W_SA1 | rna-NM_001179337.3_SA1 | cds-NP_012076.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:502063-503931:+ | gene-YHR206W_ThermosaccDry | rna-NM_001179337.3_ThermosaccDry | cds-NP_012076.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:511073-512941:+ | gene-YHR206W_VR1 | rna-NM_001179337.3_VR1 | cds-NP_012076.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:492117-493985:+ | gene-YHR206W_ZTW1 | rna-NM_001179337.3_ZTW1 | cds-NP_012076.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:498817-500691:+ | gene-YHR206W_Sparadoxus | rna-NM_001179337.3_Sparadoxus | cds-NP_012076.3_Sparadoxus | 91.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |