Gene name: SKM1
Reference locus (S288C): YOL113W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase SKM1; Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication
Top 10 interactors (score): CDC42 (0.999); BEM1 (0.966); SLT2 (0.946); SMK1 (0.945); HOG1 (0.943); MYO1 (0.923); STE20 (0.915); MLC1 (0.914); MLC2 (0.914); STE11 (0.909); STE4 (0.886); STE7 (0.867); CLA4 (0.858); RHO1 (0.84); CDC24 (0.817); STE18 (0.811); YIL082W-A (0.807); RSR1 (0.722); SHC1 (0.697); LRG1 (0.69)
Homologues (species, bitscore): PAK1 (Homo sapiens, 362.8); Pak1 (Mus musculus, 367.1); pak2a (Danio rerio, 354.8); pak3 (Xenopus tropicalis, 368.2); Pak (Drosophila melanogaster, 310.1); pak-1 (Caenorhabditis elegans, 337.0); AT3G15220 (Arabidopsis thaliana, 188.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:92970-94937:+ | gene-YOL113W_AKU4011 | rna-NM_001183367.1_AKU4011 | cds-NP_014528.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:58600-60567:+ | gene-YOL113W_BG1 | rna-NM_001183367.1_BG1 | cds-NP_014528.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:94243-96210:+ | gene-YOL113W_Bruggeman | rna-NM_001183367.1_Bruggeman | cds-NP_014528.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:93435-95402:+ | gene-YOL113W_CAT1 | rna-NM_001183367.1_CAT1 | cds-NP_014528.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:87444-89411:+ | gene-YOL113W_CBS1585 | rna-NM_001183367.1_CBS1585 | cds-NP_014528.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:93282-95249:+ | gene-YOL113W_CBS436 | rna-NM_001183367.1_CBS436 | cds-NP_014528.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:87308-89275:+ | gene-YOL113W_CBS6412 | rna-NM_001183367.1_CBS6412 | cds-NP_014528.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:93776-95743:+ | gene-YOL113W_CBS6413 | rna-NM_001183367.1_CBS6413 | cds-NP_014528.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:104221-106188:+ | gene-YOL113W_CENPK1137D | rna-NM_001183367.1_CENPK1137D | cds-NP_014528.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:91242-93209:+ | gene-YOL113W_EthanolRed | rna-NM_001183367.1_EthanolRed | cds-NP_014528.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:93271-95238:+ | gene-YOL113W_FaliES1 | rna-NM_001183367.1_FaliES1 | cds-NP_014528.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000203.1:10480-12447:+ | gene-YOL113W_JAY291 | rna-NM_001183367.1_JAY291 | cds-NP_014528.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:98885-100852:+ | gene-YOL113W_MUCL30387 | rna-NM_001183367.1_MUCL30387 | cds-NP_014528.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:101886-103853:+ | gene-YOL113W_MUCL30388 | rna-NM_001183367.1_MUCL30388 | cds-NP_014528.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:95383-97350:+ | gene-YOL113W_MUCL39482 | rna-NM_001183367.1_MUCL39482 | cds-NP_014528.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:111514-113481:+ | gene-YOL113W_MUCL42920 | rna-NM_001183367.1_MUCL42920 | cds-NP_014528.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:104215-106182:+ | gene-YOL113W_NCIM3186 | rna-NM_001183367.1_NCIM3186 | cds-NP_014528.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:101417-103384:+ | gene-YOL113W_NCYC1407 | rna-NM_001183367.1_NCYC1407 | cds-NP_014528.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:79880-81847:+ | gene-YOL113W_PE2H3 | rna-NM_001183367.1_PE2H3 | cds-NP_014528.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:96809-98776:+ | gene-YOL113W_PE2H4 | rna-NM_001183367.1_PE2H4 | cds-NP_014528.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:104326-106293:+ | gene-YOL113W_S288C | rna-NM_001183367.1_S288C | cds-NP_014528.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:77753-79720:+ | gene-YOL113W_SA1 | rna-NM_001183367.1_SA1 | cds-NP_014528.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:92409-94376:+ | gene-YOL113W_ThermosaccDry | rna-NM_001183367.1_ThermosaccDry | cds-NP_014528.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:93058-95025:+ | gene-YOL113W_VR1 | rna-NM_001183367.1_VR1 | cds-NP_014528.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:92133-94100:+ | gene-YOL113W_ZTW1 | rna-NM_001183367.1_ZTW1 | cds-NP_014528.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:94922-96890:+ | gene-YOL113W_Sparadoxus | rna-NM_001183367.1_Sparadoxus | cds-NP_014528.1_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |