Gene name: SKI7
Reference locus (S288C): YOR076C
Gene biotype: protein_coding
Description: Superkiller protein 7; GTP-binding protein that couples the Ski complex and exosome; putative pseudo-translational GTPase involved in 3'-to-5' mRNA decay pathway; interacts with both the cytoplasmic exosome and the Ski complex; eRF3-like domain targets nonstop mRNA for degradation; null mutants have a superkiller phenotype; SKI7 has a paralog, HBS1, that arose from the whole genome duplication; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family
Top 10 interactors (score): RRP42 (0.999); RRP4 (0.999); SKI6 (0.999); DOM34 (0.999); CSL4 (0.999); RRP40 (0.999); RRP6 (0.999); RRP43 (0.999); RRP46 (0.999); MTR3 (0.999); DIS3 (0.999); RRP45 (0.999); SKI2 (0.997); SKI8 (0.996); SKI3 (0.996); NAM7 (0.987); CAM1 (0.982); XRN1 (0.978); SUP45 (0.945); RKR1 (0.94)
Homologues (species, bitscore): HBS1L (Homo sapiens, 97.8); Hbs1l (Mus musculus, 96.3); hbs1l (Danio rerio, 106.3); hbs1l (Xenopus tropicalis, 100.5); HBS1 (Drosophila melanogaster, 90.5); K07A12.4 (Caenorhabditis elegans, 77.8); AT5G10630 (Arabidopsis thaliana, 82.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:453726-455969:- | gene-YOR076C_AKU4011 | rna-NM_001183495.1_AKU4011 | cds-NP_014719.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:123727-125970:+ | gene-YOR076C_BG1 | rna-NM_001183495.1_BG1 | cds-NP_014719.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:456443-458686:- | gene-YOR076C_Bruggeman | rna-NM_001183495.1_Bruggeman | cds-NP_014719.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:455211-457454:- | gene-YOR076C_CAT1 | rna-NM_001183495.1_CAT1 | cds-NP_014719.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:448445-450688:- | gene-YOR076C_CBS1585 | rna-NM_001183495.1_CBS1585 | cds-NP_014719.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:453243-455486:- | gene-YOR076C_CBS436 | rna-NM_001183495.1_CBS436 | cds-NP_014719.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:447735-449978:- | gene-YOR076C_CBS6412 | rna-NM_001183495.1_CBS6412 | cds-NP_014719.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:455052-457295:- | gene-YOR076C_CBS6413 | rna-NM_001183495.1_CBS6413 | cds-NP_014719.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:469374-471617:- | gene-YOR076C_CENPK1137D | rna-NM_001183495.1_CENPK1137D | cds-NP_014719.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:450437-452680:- | gene-YOR076C_EthanolRed | rna-NM_001183495.1_EthanolRed | cds-NP_014719.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:453766-456009:- | gene-YOR076C_FaliES1 | rna-NM_001183495.1_FaliES1 | cds-NP_014719.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000231.1:15978-18220:+ | gene-YOR076C_JAY291 | rna-NM_001183495.1_JAY291 | cds-NP_014719.1_JAY291 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:461226-463469:- | gene-YOR076C_MUCL30387 | rna-NM_001183495.1_MUCL30387 | cds-NP_014719.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:465883-468126:- | gene-YOR076C_MUCL30388 | rna-NM_001183495.1_MUCL30388 | cds-NP_014719.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:456160-458403:- | gene-YOR076C_MUCL39482 | rna-NM_001183495.1_MUCL39482 | cds-NP_014719.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:471704-473947:- | gene-YOR076C_MUCL42920 | rna-NM_001183495.1_MUCL42920 | cds-NP_014719.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:469266-471509:- | gene-YOR076C_NCIM3186 | rna-NM_001183495.1_NCIM3186 | cds-NP_014719.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:462832-465075:- | gene-YOR076C_NCYC1407 | rna-NM_001183495.1_NCYC1407 | cds-NP_014719.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:461479-463722:- | gene-YOR076C_PE2H3 | rna-NM_001183495.1_PE2H3 | cds-NP_014719.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:471855-474098:- | gene-YOR076C_PE2H4 | rna-NM_001183495.1_PE2H4 | cds-NP_014719.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:469377-471620:- | gene-YOR076C_S288C | rna-NM_001183495.1_S288C | cds-NP_014719.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000091.1:16007-18250:+ | gene-YOR076C_SA1 | rna-NM_001183495.1_SA1 | cds-NP_014719.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:452922-455165:- | gene-YOR076C_ThermosaccDry | rna-NM_001183495.1_ThermosaccDry | cds-NP_014719.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:454417-456660:- | gene-YOR076C_VR1 | rna-NM_001183495.1_VR1 | cds-NP_014719.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:186919-189162:- | gene-YOR076C_ZTW1 | rna-NM_001183495.1_ZTW1 | cds-NP_014719.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:458543-460786:- | gene-YOR076C_Sparadoxus | rna-NM_001183495.1_Sparadoxus | cds-NP_014719.1_Sparadoxus | 84.9 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |