Gene name: SIR1
Reference locus (S288C): YKR101W
Gene biotype: protein_coding
Description: Regulatory protein SIR1; Protein involved in silencing at mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin
Top 10 interactors (score): SIR2 (0.999); SIR3 (0.999); ORC1 (0.999); SIR4 (0.999); SAS2 (0.941); CDC14 (0.933); NET1 (0.906); RAP1 (0.874); NAT1 (0.871); HHF1 (0.856); ARD1 (0.84); DOT1 (0.822); YKU70 (0.785); ASF1 (0.78); HHT2 (0.772); HHT1 (0.771); SAS4 (0.77); YKU80 (0.77); HHF2 (0.76); SAS5 (0.758)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:626489-628453:+ | gene-YKR101W_AKU4011 | rna-NM_001179891.3_AKU4011 | cds-NP_013027.4_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:15619-17583:- | gene-YKR101W_BG1 | rna-NM_001179891.3_BG1 | cds-NP_013027.4_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:649100-651064:+ | gene-YKR101W_Bruggeman | rna-NM_001179891.3_Bruggeman | cds-NP_013027.4_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:646638-648602:+ | gene-YKR101W_CAT1 | rna-NM_001179891.3_CAT1 | cds-NP_013027.4_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:638971-640935:+ | gene-YKR101W_CBS1585 | rna-NM_001179891.3_CBS1585 | cds-NP_013027.4_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:637385-639349:+ | gene-YKR101W_CBS436 | rna-NM_001179891.3_CBS436 | cds-NP_013027.4_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:622259-624223:+ | gene-YKR101W_CBS6412 | rna-NM_001179891.3_CBS6412 | cds-NP_013027.4_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:638791-640755:+ | gene-YKR101W_CBS6413 | rna-NM_001179891.3_CBS6413 | cds-NP_013027.4_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:640192-642156:+ | gene-YKR101W_CENPK1137D | rna-NM_001179891.3_CENPK1137D | cds-NP_013027.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:636377-638341:+ | gene-YKR101W_EthanolRed | rna-NM_001179891.3_EthanolRed | cds-NP_013027.4_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:640273-642237:+ | gene-YKR101W_FaliES1 | rna-NM_001179891.3_FaliES1 | cds-NP_013027.4_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000426.1:2729-4693:- | gene-YKR101W_JAY291 | rna-NM_001179891.3_JAY291 | cds-NP_013027.4_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:648611-650575:+ | gene-YKR101W_MUCL30387 | rna-NM_001179891.3_MUCL30387 | cds-NP_013027.4_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:642925-644889:+ | gene-YKR101W_MUCL30388 | rna-NM_001179891.3_MUCL30388 | cds-NP_013027.4_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:637810-639774:+ | gene-YKR101W_MUCL39482 | rna-NM_001179891.3_MUCL39482 | cds-NP_013027.4_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:643869-645833:+ | gene-YKR101W_MUCL42920 | rna-NM_001179891.3_MUCL42920 | cds-NP_013027.4_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:640529-642493:+ | gene-YKR101W_NCIM3186 | rna-NM_001179891.3_NCIM3186 | cds-NP_013027.4_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:638233-640197:+ | gene-YKR101W_NCYC1407 | rna-NM_001179891.3_NCYC1407 | cds-NP_013027.4_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:663485-665449:+ | gene-YKR101W_PE2H3 | rna-NM_001179891.3_PE2H3 | cds-NP_013027.4_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:647921-649885:+ | gene-YKR101W_PE2H4 | rna-NM_001179891.3_PE2H4 | cds-NP_013027.4_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:640540-642504:+ | gene-YKR101W_S288C | rna-NM_001179891.3_S288C | cds-NP_013027.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000029.1:16054-18018:- | gene-YKR101W_SA1 | rna-NM_001179891.3_SA1 | cds-NP_013027.4_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:639518-641482:+ | gene-YKR101W_ThermosaccDry | rna-NM_001179891.3_ThermosaccDry | cds-NP_013027.4_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:638806-640770:+ | gene-YKR101W_VR1 | rna-NM_001179891.3_VR1 | cds-NP_013027.4_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:636481-638445:+ | gene-YKR101W_ZTW1 | rna-NM_001179891.3_ZTW1 | cds-NP_013027.4_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:661866-663818:+ | gene-YKR101W_Sparadoxus | rna-NM_001179891.3_Sparadoxus | cds-NP_013027.4_Sparadoxus | 82.0 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |