Gene name: SIP3
Reference locus (S288C): YNL257C
Gene biotype: protein_coding
Description: Membrane-anchored lipid-binding protein SIP3; Putative sterol transfer protein; has a probable role in retrograde transport of sterols from the plasma membrane to the ER; co-localizes to puncta in the cortical ER with Ysp2p; contains GRAM, StART-like (VASt) and two PH-like domains; one of 6 StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes; previously identified as a transcription cofactor that interacts with DNA-bound Snf1p
Top 10 interactors (score): LAM4 (0.92); YSP2 (0.896); VID27 (0.782); LAM5 (0.769); SPO71 (0.765); LAM6 (0.751); MPA43 (0.719); SNF1 (0.694); RBH1 (0.654); GYP7 (0.631); DGR2 (0.581); YNL247W (0.573); RBH2 (0.572); LNP1 (0.562); TPH3 (0.481); AGE2 (0.477); YMR102C (0.46); EIS1 (0.457); GLO4 (0.454); MNT3 (0.45)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:154401-158090:- | gene-YNL257C_AKU4011 | rna-NM_001183095.1_AKU4011 | cds-NP_014142.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:58359-62048:- | gene-YNL257C_BG1 | rna-NM_001183095.1_BG1 | cds-NP_014142.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:164224-167913:- | gene-YNL257C_Bruggeman | rna-NM_001183095.1_Bruggeman | cds-NP_014142.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:171519-175208:- | gene-YNL257C_CAT1 | rna-NM_001183095.1_CAT1 | cds-NP_014142.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:154801-158490:- | gene-YNL257C_CBS1585 | rna-NM_001183095.1_CBS1585 | cds-NP_014142.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:149903-153592:- | gene-YNL257C_CBS436 | rna-NM_001183095.1_CBS436 | cds-NP_014142.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:151212-154901:- | gene-YNL257C_CBS6412 | rna-NM_001183095.1_CBS6412 | cds-NP_014142.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:151494-155183:- | gene-YNL257C_CBS6413 | rna-NM_001183095.1_CBS6413 | cds-NP_014142.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:154445-158134:- | gene-YNL257C_CENPK1137D | rna-NM_001183095.1_CENPK1137D | cds-NP_014142.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:152052-155741:- | gene-YNL257C_EthanolRed | rna-NM_001183095.1_EthanolRed | cds-NP_014142.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:146787-150476:- | gene-YNL257C_FaliES1 | rna-NM_001183095.1_FaliES1 | cds-NP_014142.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:57956-61645:- | gene-YNL257C_JAY291 | rna-NM_001183095.1_JAY291 | cds-NP_014142.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:160008-163697:- | gene-YNL257C_MUCL30387 | rna-NM_001183095.1_MUCL30387 | cds-NP_014142.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:158593-162282:- | gene-YNL257C_MUCL30388 | rna-NM_001183095.1_MUCL30388 | cds-NP_014142.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:152291-155980:- | gene-YNL257C_MUCL39482 | rna-NM_001183095.1_MUCL39482 | cds-NP_014142.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:154559-158248:- | gene-YNL257C_MUCL42920 | rna-NM_001183095.1_MUCL42920 | cds-NP_014142.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:160600-164289:- | gene-YNL257C_NCIM3186 | rna-NM_001183095.1_NCIM3186 | cds-NP_014142.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:154396-158085:- | gene-YNL257C_NCYC1407 | rna-NM_001183095.1_NCYC1407 | cds-NP_014142.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:151297-154986:- | gene-YNL257C_PE2H3 | rna-NM_001183095.1_PE2H3 | cds-NP_014142.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:150685-154374:- | gene-YNL257C_PE2H4 | rna-NM_001183095.1_PE2H4 | cds-NP_014142.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:160631-164320:- | gene-YNL257C_S288C | rna-NM_001183095.1_S288C | cds-NP_014142.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:87970-91659:+ | gene-YNL257C_SA1 | rna-NM_001183095.1_SA1 | cds-NP_014142.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:147643-151332:- | gene-YNL257C_ThermosaccDry | rna-NM_001183095.1_ThermosaccDry | cds-NP_014142.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:166554-170243:- | gene-YNL257C_VR1 | rna-NM_001183095.1_VR1 | cds-NP_014142.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:57975-61664:- | gene-YNL257C_ZTW1 | rna-NM_001183095.1_ZTW1 | cds-NP_014142.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:157862-161554:- | gene-YNL257C_Sparadoxus | rna-NM_001183095.1_Sparadoxus | cds-NP_014142.1_Sparadoxus | 89.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |