Gene name: SIP2
Reference locus (S288C): YGL208W
Gene biotype: protein_coding
Description: One of three beta subunits of the Snf1 kinase complex; involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane; SIP2 has a paralog, GAL83, that arose from the whole genome duplication
Top 10 interactors (score): SNF4 (0.999); SNF1 (0.999); GAL83 (0.991); SIP1 (0.988); SAK1 (0.947); VPS34 (0.912); TOS3 (0.911); VPS30 (0.909); VPS15 (0.9); SDS24 (0.878); ELM1 (0.874); SDS23 (0.867); MIG1 (0.844); SIP4 (0.838); KIN4 (0.806); CAT8 (0.8); YPL150W (0.792); FRK1 (0.792); ADR1 (0.769); GLC7 (0.748)
Homologues (species, bitscore): PRKAB2 (Homo sapiens, 107.1); Prkab2 (Mus musculus, 105.1); prkab1a (Danio rerio, 100.1); prkab2 (Xenopus tropicalis, 110.9); alc (Drosophila melanogaster, 85.9); aakb-1 (Caenorhabditis elegans, 80.9); AT4G16360 (Arabidopsis thaliana, 66.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:98683-99930:+ | gene-YGL208W_AKU4011 | rna-NM_001181073.2_AKU4011 | cds-NP_011307.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:91746-92993:+ | gene-YGL208W_BG1 | rna-NM_001181073.2_BG1 | cds-NP_011307.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:99192-100265:+ | gene-YGL208W_Bruggeman | rna-NM_001181073.2_Bruggeman | cds-NP_011307.1_Bruggeman | 75.3 | 84.5 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:97858-99105:+ | gene-YGL208W_CAT1 | rna-NM_001181073.2_CAT1 | cds-NP_011307.1_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:102988-104235:+ | gene-YGL208W_CBS1585 | rna-NM_001181073.2_CBS1585 | cds-NP_011307.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:98554-99801:+ | gene-YGL208W_CBS436 | rna-NM_001181073.2_CBS436 | cds-NP_011307.1_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:90119-91366:+ | gene-YGL208W_CBS6412 | rna-NM_001181073.2_CBS6412 | cds-NP_011307.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:96823-98070:+ | gene-YGL208W_CBS6413 | rna-NM_001181073.2_CBS6413 | cds-NP_011307.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:97368-98615:+ | gene-YGL208W_CENPK1137D | rna-NM_001181073.2_CENPK1137D | cds-NP_011307.1_CENPK1137D | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:89488-90735:+ | gene-YGL208W_EthanolRed | rna-NM_001181073.2_EthanolRed | cds-NP_011307.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:90331-91578:+ | gene-YGL208W_FaliES1 | rna-NM_001181073.2_FaliES1 | cds-NP_011307.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:16737-17984:+ | gene-YGL208W_JAY291 | rna-NM_001181073.2_JAY291 | cds-NP_011307.1_JAY291 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:99108-100355:+ | gene-YGL208W_MUCL30387 | rna-NM_001181073.2_MUCL30387 | cds-NP_011307.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:101285-102532:+ | gene-YGL208W_MUCL30388 | rna-NM_001181073.2_MUCL30388 | cds-NP_011307.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:99501-100748:+ | gene-YGL208W_MUCL39482 | rna-NM_001181073.2_MUCL39482 | cds-NP_011307.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:102606-103853:+ | gene-YGL208W_MUCL42920 | rna-NM_001181073.2_MUCL42920 | cds-NP_011307.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:97338-98585:+ | gene-YGL208W_NCIM3186 | rna-NM_001181073.2_NCIM3186 | cds-NP_011307.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:91223-92470:+ | gene-YGL208W_NCYC1407 | rna-NM_001181073.2_NCYC1407 | cds-NP_011307.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:94051-95298:+ | gene-YGL208W_PE2H3 | rna-NM_001181073.2_PE2H3 | cds-NP_011307.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:93599-94846:+ | gene-YGL208W_PE2H4 | rna-NM_001181073.2_PE2H4 | cds-NP_011307.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:97338-98585:+ | gene-YGL208W_S288C | rna-NM_001181073.2_S288C | cds-NP_011307.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:276697-277944:- | gene-YGL208W_SA1 | rna-NM_001181073.2_SA1 | cds-NP_011307.1_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:90592-91839:+ | gene-YGL208W_ThermosaccDry | rna-NM_001181073.2_ThermosaccDry | cds-NP_011307.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:98466-99713:+ | gene-YGL208W_VR1 | rna-NM_001181073.2_VR1 | cds-NP_011307.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:89628-90875:+ | gene-YGL208W_ZTW1 | rna-NM_001181073.2_ZTW1 | cds-NP_011307.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:96848-98083:+ | gene-YGL208W_Sparadoxus | rna-NM_001181073.2_Sparadoxus | cds-NP_011307.1_Sparadoxus | 88.1 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |