Gene name: SIN3
Reference locus (S288C): YOL004W
Gene biotype: protein_coding
Description: Transcriptional regulatory protein SIN3; Component of both the Rpd3S and Rpd3L histone deacetylase complexes; involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity
Top 10 interactors (score): SDS3 (0.999); EAF3 (0.999); HOS2 (0.999); RPD3 (0.999); RCO1 (0.999); SNT1 (0.999); PHO23 (0.999); UME1 (0.998); UME6 (0.998); SAP30 (0.997); HAT2 (0.995); CTI6 (0.994); RXT3 (0.993); HOS1 (0.992); RXT2 (0.991); DEP1 (0.985); ASH1 (0.984); JHD2 (0.984); MSI1 (0.973); SET3 (0.965)
Homologues (species, bitscore): SIN3A (Homo sapiens, 467.2); Sin3a (Mus musculus, 465.3); sin3ab (Danio rerio, 459.9); sin3a (Xenopus tropicalis, 473.8); Sin3A (Drosophila melanogaster, 384.8); sin-3 (Caenorhabditis elegans, 159.1); SNL1 (Arabidopsis thaliana, 243.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:301331-305941:+ | gene-YOL004W_AKU4011 | rna-NM_001183258.1_AKU4011 | cds-NP_014639.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:116893-121503:+ | gene-YOL004W_BG1 | rna-NM_001183258.1_BG1 | cds-NP_014639.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:304106-308716:+ | gene-YOL004W_Bruggeman | rna-NM_001183258.1_Bruggeman | cds-NP_014639.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:302239-306849:+ | gene-YOL004W_CAT1 | rna-NM_001183258.1_CAT1 | cds-NP_014639.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:296007-300617:+ | gene-YOL004W_CBS1585 | rna-NM_001183258.1_CBS1585 | cds-NP_014639.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:300244-304854:+ | gene-YOL004W_CBS436 | rna-NM_001183258.1_CBS436 | cds-NP_014639.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:295311-299921:+ | gene-YOL004W_CBS6412 | rna-NM_001183258.1_CBS6412 | cds-NP_014639.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:302844-307454:+ | gene-YOL004W_CBS6413 | rna-NM_001183258.1_CBS6413 | cds-NP_014639.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:316656-321266:+ | gene-YOL004W_CENPK1137D | rna-NM_001183258.1_CENPK1137D | cds-NP_014639.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:298096-302706:+ | gene-YOL004W_EthanolRed | rna-NM_001183258.1_EthanolRed | cds-NP_014639.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:301423-306033:+ | gene-YOL004W_FaliES1 | rna-NM_001183258.1_FaliES1 | cds-NP_014639.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000015.1:23233-27843:- | gene-YOL004W_JAY291 | rna-NM_001183258.1_JAY291 | cds-NP_014639.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:308321-312931:+ | gene-YOL004W_MUCL30387 | rna-NM_001183258.1_MUCL30387 | cds-NP_014639.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:311757-316367:+ | gene-YOL004W_MUCL30388 | rna-NM_001183258.1_MUCL30388 | cds-NP_014639.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:303490-308100:+ | gene-YOL004W_MUCL39482 | rna-NM_001183258.1_MUCL39482 | cds-NP_014639.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:318344-322954:+ | gene-YOL004W_MUCL42920 | rna-NM_001183258.1_MUCL42920 | cds-NP_014639.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:316827-321437:+ | gene-YOL004W_NCIM3186 | rna-NM_001183258.1_NCIM3186 | cds-NP_014639.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:310176-314786:+ | gene-YOL004W_NCYC1407 | rna-NM_001183258.1_NCYC1407 | cds-NP_014639.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:304833-309443:+ | gene-YOL004W_PE2H3 | rna-NM_001183258.1_PE2H3 | cds-NP_014639.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:315212-319822:+ | gene-YOL004W_PE2H4 | rna-NM_001183258.1_PE2H4 | cds-NP_014639.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:316938-321548:+ | gene-YOL004W_S288C | rna-NM_001183258.1_S288C | cds-NP_014639.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:284920-289530:+ | gene-YOL004W_SA1 | rna-NM_001183258.1_SA1 | cds-NP_014639.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:299994-304604:+ | gene-YOL004W_ThermosaccDry | rna-NM_001183258.1_ThermosaccDry | cds-NP_014639.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:300795-305405:+ | gene-YOL004W_VR1 | rna-NM_001183258.1_VR1 | cds-NP_014639.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:34659-39269:+ | gene-YOL004W_ZTW1 | rna-NM_001183258.1_ZTW1 | cds-NP_014639.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:308281-312993:+ | gene-YOL004W_Sparadoxus | rna-NM_001183258.1_Sparadoxus | cds-NP_014639.1_Sparadoxus | 87.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |