SIL1 (YOL031C)


Gene profile

Gene name: SIL1
Reference locus (S288C): YOL031C
Gene biotype: protein_coding

Description: Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; required for protein translocation into the endoplasmic reticulum (ER); homolog of Yarrowia lipolytica SLS1; GrpE-like protein; Belongs to the SIL1 family

Top 10 interactors (score): KAR2 (0.999); LHS1 (0.997); MBF1 (0.9); STI1 (0.898); SHP1 (0.887); RPL5 (0.88); RPL25 (0.88); RPS3 (0.879); SEC61 (0.878); MRPS9 (0.862); RTC6 (0.858); MNP1 (0.858); MRPL8 (0.856); MRP17 (0.847); YDR274C (0.845); SEC63 (0.844); RPL38 (0.82); SSE1 (0.819); HCH1 (0.807); AHA1 (0.807)

Homologues (species, bitscore): SIL1 (Homo sapiens, 53.1); CG10420 (Drosophila melanogaster, 51.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:250626-251891:- gene-YOL031C_AKU4011 rna-NM_001183285.1_AKU4011 cds-NP_014611.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:66245-67510:- gene-YOL031C_BG1 rna-NM_001183285.1_BG1 cds-NP_014611.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:253479-254744:- gene-YOL031C_Bruggeman rna-NM_001183285.1_Bruggeman cds-NP_014611.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:251341-252606:- gene-YOL031C_CAT1 rna-NM_001183285.1_CAT1 cds-NP_014611.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:245296-246561:- gene-YOL031C_CBS1585 rna-NM_001183285.1_CBS1585 cds-NP_014611.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:249573-250838:- gene-YOL031C_CBS436 rna-NM_001183285.1_CBS436 cds-NP_014611.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:244660-245925:- gene-YOL031C_CBS6412 rna-NM_001183285.1_CBS6412 cds-NP_014611.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:252179-253444:- gene-YOL031C_CBS6413 rna-NM_001183285.1_CBS6413 cds-NP_014611.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:265964-267229:- gene-YOL031C_CENPK1137D rna-NM_001183285.1_CENPK1137D cds-NP_014611.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:247614-248879:- gene-YOL031C_EthanolRed rna-NM_001183285.1_EthanolRed cds-NP_014611.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:250530-251795:- gene-YOL031C_FaliES1 rna-NM_001183285.1_FaliES1 cds-NP_014611.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:14664-15929:+ gene-YOL031C_JAY291 rna-NM_001183285.1_JAY291 cds-NP_014611.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:256501-257766:- gene-YOL031C_MUCL30387 rna-NM_001183285.1_MUCL30387 cds-NP_014611.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:260852-262117:- gene-YOL031C_MUCL30388 rna-NM_001183285.1_MUCL30388 cds-NP_014611.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:252781-254046:- gene-YOL031C_MUCL39482 rna-NM_001183285.1_MUCL39482 cds-NP_014611.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:267712-268977:- gene-YOL031C_MUCL42920 rna-NM_001183285.1_MUCL42920 cds-NP_014611.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:266153-267418:- gene-YOL031C_NCIM3186 rna-NM_001183285.1_NCIM3186 cds-NP_014611.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:259521-260786:- gene-YOL031C_NCYC1407 rna-NM_001183285.1_NCYC1407 cds-NP_014611.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:241939-243204:- gene-YOL031C_PE2H3 rna-NM_001183285.1_PE2H3 cds-NP_014611.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:252913-254178:- gene-YOL031C_PE2H4 rna-NM_001183285.1_PE2H4 cds-NP_014611.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:266264-267529:- gene-YOL031C_S288C rna-NM_001183285.1_S288C cds-NP_014611.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:234263-235528:- gene-YOL031C_SA1 rna-NM_001183285.1_SA1 cds-NP_014611.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:249101-250366:- gene-YOL031C_ThermosaccDry rna-NM_001183285.1_ThermosaccDry cds-NP_014611.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:249164-250429:- gene-YOL031C_VR1 rna-NM_001183285.1_VR1 cds-NP_014611.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:248963-250228:- gene-YOL031C_ZTW1 rna-NM_001183285.1_ZTW1 cds-NP_014611.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:257350-258615:- gene-YOL031C_Sparadoxus rna-NM_001183285.1_Sparadoxus cds-NP_014611.1_Sparadoxus 87.8 99.9 Verified 1 1 1 False True False False False

Additional files