SIF2 (YBR103W)


Gene profile

Gene name: SIF2
Reference locus (S288C): YBR103W
Gene biotype: protein_coding

Description: SIR4-interacting protein SIF2; WD40 repeat-containing subunit of Set3C histone deacetylase complex; complex represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus

Top 10 interactors (score): SNT1 (0.999); SET3 (0.999); HOS4 (0.999); HOS2 (0.999); CPR1 (0.999); RPD3 (0.996); HST1 (0.974); CTI6 (0.961); PHO23 (0.957); SIN3 (0.954); HHT2 (0.943); SDS3 (0.936); SAP30 (0.935); HTB1 (0.926); HTB2 (0.925); UME6 (0.922); UME1 (0.92); HTA1 (0.92); HTA2 (0.92); DEP1 (0.919)

Homologues (species, bitscore): TBL1XR1 (Homo sapiens, 171.4); Tbl1xr1 (Mus musculus, 171.0); tbl1xr1b (Danio rerio, 168.3); tbl1xr1 (Xenopus tropicalis, 149.8); ebi (Drosophila melanogaster, 122.5); sel-10 (Caenorhabditis elegans, 65.1); HOS15 (Arabidopsis thaliana, 130.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:430071-431678:+ gene-YBR103W_AKU4011 rna-NM_001178451.1_AKU4011 cds-NP_009661.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:421113-422720:+ gene-YBR103W_BG1 rna-NM_001178451.1_BG1 cds-NP_009661.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:431849-433456:+ gene-YBR103W_Bruggeman rna-NM_001178451.1_Bruggeman cds-NP_009661.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:434620-436227:+ gene-YBR103W_CAT1 rna-NM_001178451.1_CAT1 cds-NP_009661.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:422356-423963:+ gene-YBR103W_CBS1585 rna-NM_001178451.1_CBS1585 cds-NP_009661.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:430478-432085:+ gene-YBR103W_CBS436 rna-NM_001178451.1_CBS436 cds-NP_009661.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:520584-522191:+ gene-YBR103W_CBS6412 rna-NM_001178451.1_CBS6412 cds-NP_009661.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:427495-429102:+ gene-YBR103W_CBS6413 rna-NM_001178451.1_CBS6413 cds-NP_009661.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:439609-441216:+ gene-YBR103W_CENPK1137D rna-NM_001178451.1_CENPK1137D cds-NP_009661.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:556866-558473:+ gene-YBR103W_EthanolRed rna-NM_001178451.1_EthanolRed cds-NP_009661.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:446149-447756:+ gene-YBR103W_FaliES1 rna-NM_001178451.1_FaliES1 cds-NP_009661.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000312.1:17053-18660:+ gene-YBR103W_JAY291 rna-NM_001178451.1_JAY291 cds-NP_009661.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:433884-435491:+ gene-YBR103W_MUCL30387 rna-NM_001178451.1_MUCL30387 cds-NP_009661.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:432883-434490:+ gene-YBR103W_MUCL30388 rna-NM_001178451.1_MUCL30388 cds-NP_009661.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:420499-422106:+ gene-YBR103W_MUCL39482 rna-NM_001178451.1_MUCL39482 cds-NP_009661.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:429563-431170:+ gene-YBR103W_MUCL42920 rna-NM_001178451.1_MUCL42920 cds-NP_009661.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:447506-449113:+ gene-YBR103W_NCIM3186 rna-NM_001178451.1_NCIM3186 cds-NP_009661.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:423278-424885:+ gene-YBR103W_NCYC1407 rna-NM_001178451.1_NCYC1407 cds-NP_009661.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:435898-437505:+ gene-YBR103W_PE2H3 rna-NM_001178451.1_PE2H3 cds-NP_009661.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:433574-435181:+ gene-YBR103W_PE2H4 rna-NM_001178451.1_PE2H4 cds-NP_009661.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:447709-449316:+ gene-YBR103W_S288C rna-NM_001178451.1_S288C cds-NP_009661.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000017.1:28394-30001:- gene-YBR103W_SA1 rna-NM_001178451.1_SA1 cds-NP_009661.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:445156-446763:+ gene-YBR103W_ThermosaccDry rna-NM_001178451.1_ThermosaccDry cds-NP_009661.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:427159-428766:+ gene-YBR103W_VR1 rna-NM_001178451.1_VR1 cds-NP_009661.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:420817-422424:+ gene-YBR103W_ZTW1 rna-NM_001178451.1_ZTW1 cds-NP_009661.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:457710-459335:+ gene-YBR103W_Sparadoxus rna-NM_001178451.1_Sparadoxus cds-NP_009661.1_Sparadoxus 86.7 99.9 Verified 1 1 1 False True False False False

Additional files