Gene name: SHY1
Reference locus (S288C): YGR112W
Gene biotype: protein_coding
Description: Cytochrome oxidase assembly protein SHY1; Mitochondrial inner membrane protein required for complex IV assembly; associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome; complex IV is also known as cytochrome c oxidase
Top 10 interactors (score): COX15 (0.998); COX10 (0.994); MSS51 (0.991); COX11 (0.987); COX6 (0.983); COA3 (0.971); COA2 (0.965); COX1 (0.954); COX5A (0.954); COX14 (0.942); COR1 (0.94); COA1 (0.937); SCO2 (0.931); OXA1 (0.931); PET309 (0.925); COX17 (0.91); QCR2 (0.908); COX2 (0.905); COX20 (0.901); COX12 (0.895)
Homologues (species, bitscore): SURF1 (Homo sapiens, 112.1); Surf1 (Mus musculus, 104.8); surf1 (Danio rerio, 102.1); Surf1 (Drosophila melanogaster, 106.3); sft-1 (Caenorhabditis elegans, 95.5); SURF1 (Arabidopsis thaliana, 57.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:696673-697860:+ | gene-YGR112W_AKU4011 | rna-NM_001181241.1_AKU4011 | cds-NP_011627.1_AKU4011 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000188.1:5139-6308:+ | gene-YGR112W_BG1 | rna-NM_001181241.1_BG1 | cds-NP_011627.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:698355-699524:+ | gene-YGR112W_Bruggeman | rna-NM_001181241.1_Bruggeman | cds-NP_011627.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:696558-697727:+ | gene-YGR112W_CAT1 | rna-NM_001181241.1_CAT1 | cds-NP_011627.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:697663-698850:+ | gene-YGR112W_CBS1585 | rna-NM_001181241.1_CBS1585 | cds-NP_011627.1_CBS1585 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:699290-700459:+ | gene-YGR112W_CBS436 | rna-NM_001181241.1_CBS436 | cds-NP_011627.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:689332-690519:+ | gene-YGR112W_CBS6412 | rna-NM_001181241.1_CBS6412 | cds-NP_011627.1_CBS6412 | 98.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:694266-695453:+ | gene-YGR112W_CBS6413 | rna-NM_001181241.1_CBS6413 | cds-NP_011627.1_CBS6413 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:717076-718245:+ | gene-YGR112W_CENPK1137D | rna-NM_001181241.1_CENPK1137D | cds-NP_011627.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:683774-684943:+ | gene-YGR112W_EthanolRed | rna-NM_001181241.1_EthanolRed | cds-NP_011627.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:687565-688752:+ | gene-YGR112W_FaliES1 | rna-NM_001181241.1_FaliES1 | cds-NP_011627.1_FaliES1 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000092.1:8905-10074:- | gene-YGR112W_JAY291 | rna-NM_001181241.1_JAY291 | cds-NP_011627.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:697081-698250:+ | gene-YGR112W_MUCL30387 | rna-NM_001181241.1_MUCL30387 | cds-NP_011627.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:698167-699336:+ | gene-YGR112W_MUCL30388 | rna-NM_001181241.1_MUCL30388 | cds-NP_011627.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:693390-694577:+ | gene-YGR112W_MUCL39482 | rna-NM_001181241.1_MUCL39482 | cds-NP_011627.1_MUCL39482 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:703177-704346:+ | gene-YGR112W_MUCL42920 | rna-NM_001181241.1_MUCL42920 | cds-NP_011627.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:717358-718527:+ | gene-YGR112W_NCIM3186 | rna-NM_001181241.1_NCIM3186 | cds-NP_011627.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:688083-689270:+ | gene-YGR112W_NCYC1407 | rna-NM_001181241.1_NCYC1407 | cds-NP_011627.1_NCYC1407 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:701653-702822:+ | gene-YGR112W_PE2H3 | rna-NM_001181241.1_PE2H3 | cds-NP_011627.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:706771-707940:+ | gene-YGR112W_PE2H4 | rna-NM_001181241.1_PE2H4 | cds-NP_011627.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:717358-718527:+ | gene-YGR112W_S288C | rna-NM_001181241.1_S288C | cds-NP_011627.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:138674-139843:+ | gene-YGR112W_SA1 | rna-NM_001181241.1_SA1 | cds-NP_011627.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:707945-709132:+ | gene-YGR112W_ThermosaccDry | rna-NM_001181241.1_ThermosaccDry | cds-NP_011627.1_ThermosaccDry | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:810371-811540:+ | gene-YGR112W_VR1 | rna-NM_001181241.1_VR1 | cds-NP_011627.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:10339-11526:+ | gene-YGR112W_ZTW1 | rna-NM_001181241.1_ZTW1 | cds-NP_011627.1_ZTW1 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:697801-698970:+ | gene-YGR112W_Sparadoxus | rna-NM_001181241.1_Sparadoxus | cds-NP_011627.1_Sparadoxus | 88.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |