SHU2 (YDR078C)


Gene profile

Gene name: SHU2
Reference locus (S288C): YDR078C
Gene biotype: protein_coding

Description: Suppressor of hydroxyurea sensitivity protein 2; Component of Shu complex (aka PCSS complex); Shu complex also includes Psy3, Csm2, Shu1, and promotes error-free DNA repair, Shu complex mediates inhibition of Srs2p function; promotes formation of Rad51p filaments; important for both mitotic and meiotic homologous recombination, and contains a conserved SWIM domain that is necessary for both

Top 10 interactors (score): CSM2 (0.999); PSY3 (0.999); SHU1 (0.999); RAD2 (0.931); RAD4 (0.914); TFB1 (0.902); RAD23 (0.9); RAD3 (0.9); SSL1 (0.9); RAD16 (0.9); RAD7 (0.9); ABF1 (0.9); SSL2 (0.9); SGS1 (0.888); RAD55 (0.878); RAD51 (0.875); RTR2 (0.863); RAD1 (0.839); SRS2 (0.816); RAD54 (0.814)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:579750-580421:- gene-YDR078C_AKU4011 rna-NM_001180386.1_AKU4011 cds-NP_010363.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:544916-545587:+ gene-YDR078C_BG1 rna-NM_001180386.1_BG1 cds-NP_010363.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:611981-612652:- gene-YDR078C_Bruggeman rna-NM_001180386.1_Bruggeman cds-NP_010363.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:595626-596297:- gene-YDR078C_CAT1 rna-NM_001180386.1_CAT1 cds-NP_010363.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:570766-571437:- gene-YDR078C_CBS1585 rna-NM_001180386.1_CBS1585 cds-NP_010363.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:595797-596468:- gene-YDR078C_CBS436 rna-NM_001180386.1_CBS436 cds-NP_010363.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:567181-567852:- gene-YDR078C_CBS6412 rna-NM_001180386.1_CBS6412 cds-NP_010363.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:595714-596385:- gene-YDR078C_CBS6413 rna-NM_001180386.1_CBS6413 cds-NP_010363.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:601209-601880:- gene-YDR078C_CENPK1137D rna-NM_001180386.1_CENPK1137D cds-NP_010363.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:581540-582211:- gene-YDR078C_EthanolRed rna-NM_001180386.1_EthanolRed cds-NP_010363.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:588334-589005:- gene-YDR078C_FaliES1 rna-NM_001180386.1_FaliES1 cds-NP_010363.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000358.1:42255-42926:+ gene-YDR078C_JAY291 rna-NM_001180386.1_JAY291 cds-NP_010363.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:596598-597269:- gene-YDR078C_MUCL30387 rna-NM_001180386.1_MUCL30387 cds-NP_010363.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:586910-587581:- gene-YDR078C_MUCL30388 rna-NM_001180386.1_MUCL30388 cds-NP_010363.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:572136-572807:- gene-YDR078C_MUCL39482 rna-NM_001180386.1_MUCL39482 cds-NP_010363.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:502718-503389:- gene-YDR078C_MUCL42920 rna-NM_001180386.1_MUCL42920 cds-NP_010363.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:602121-602792:- gene-YDR078C_NCIM3186 rna-NM_001180386.1_NCIM3186 cds-NP_010363.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:571061-571732:- gene-YDR078C_NCYC1407 rna-NM_001180386.1_NCYC1407 cds-NP_010363.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:590522-591193:- gene-YDR078C_PE2H3 rna-NM_001180386.1_PE2H3 cds-NP_010363.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:589827-590498:- gene-YDR078C_PE2H4 rna-NM_001180386.1_PE2H4 cds-NP_010363.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:602198-602869:- gene-YDR078C_S288C rna-NM_001180386.1_S288C cds-NP_010363.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:42462-43133:+ gene-YDR078C_SA1 rna-NM_001180386.1_SA1 cds-NP_010363.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:587865-588536:- gene-YDR078C_ThermosaccDry rna-NM_001180386.1_ThermosaccDry cds-NP_010363.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:600426-601097:- gene-YDR078C_VR1 rna-NM_001180386.1_VR1 cds-NP_010363.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:585437-586108:- gene-YDR078C_ZTW1 rna-NM_001180386.1_ZTW1 cds-NP_010363.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:590110-590781:- gene-YDR078C_Sparadoxus rna-NM_001180386.1_Sparadoxus cds-NP_010363.1_Sparadoxus 89.8 99.8 Verified 1 1 1 False True False False False

Additional files