Gene name: SHS1
Reference locus (S288C): YDL225W
Gene biotype: protein_coding
Description: Seventh homolog of septin 1; Component of the septin ring that is required for cytokinesis; present at the ends of rod-like septin hetero-oligomers; C-terminal extension is important for recruitment of Bni5p to the mother-bud neck, which in turn is required for Myo1p recruitment and cytokinesis; undergoes sumoylation and phosphorylation during mitosis; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): CDC12 (0.996); CDC3 (0.996); CDC11 (0.992); CDC10 (0.973); GIN4 (0.972); BUD4 (0.962); SCS2 (0.954); SPR3 (0.934); BNI5 (0.919); SPR28 (0.919); BNI4 (0.917); EPO1 (0.898); HOF1 (0.883); CDC28 (0.871); NIS1 (0.853); CLA4 (0.846); KCC4 (0.839); ELM1 (0.833); HSL1 (0.815); RTS1 (0.808)
Homologues (species, bitscore): SEPT7 (Homo sapiens, 172.2); Sept7 (Mus musculus, 174.9); hm:zeh0351 (Danio rerio, 176.4); sept7 (Xenopus tropicalis, 177.2); pnut (Drosophila melanogaster, 165.2); unc-59 (Caenorhabditis elegans, 164.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:35940-37595:+ | gene-YDL225W_AKU4011 | rna-NM_001180285.1_AKU4011 | cds-NP_010056.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000077.1:29507-31162:- | gene-YDL225W_BG1 | rna-NM_001180285.1_BG1 | cds-NP_010056.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:51622-53277:+ | gene-YDL225W_Bruggeman | rna-NM_001180285.1_Bruggeman | cds-NP_010056.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:271419-273074:+ | gene-YDL225W_CAT1 | rna-NM_001180285.1_CAT1 | cds-NP_010056.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:34815-36470:+ | gene-YDL225W_CBS1585 | rna-NM_001180285.1_CBS1585 | cds-NP_010056.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:249694-251349:+ | gene-YDL225W_CBS436 | rna-NM_001180285.1_CBS436 | cds-NP_010056.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:34927-36582:+ | gene-YDL225W_CBS6412 | rna-NM_001180285.1_CBS6412 | cds-NP_010056.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:52450-54105:+ | gene-YDL225W_CBS6413 | rna-NM_001180285.1_CBS6413 | cds-NP_010056.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:51111-52766:+ | gene-YDL225W_CENPK1137D | rna-NM_001180285.1_CENPK1137D | cds-NP_010056.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:48384-50039:+ | gene-YDL225W_EthanolRed | rna-NM_001180285.1_EthanolRed | cds-NP_010056.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:52711-54366:+ | gene-YDL225W_FaliES1 | rna-NM_001180285.1_FaliES1 | cds-NP_010056.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000213.1:7038-8693:+ | gene-YDL225W_JAY291 | rna-NM_001180285.1_JAY291 | cds-NP_010056.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:50562-52217:+ | gene-YDL225W_MUCL30387 | rna-NM_001180285.1_MUCL30387 | cds-NP_010056.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:258380-260035:+ | gene-YDL225W_MUCL30388 | rna-NM_001180285.1_MUCL30388 | cds-NP_010056.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:35658-37313:+ | gene-YDL225W_MUCL39482 | rna-NM_001180285.1_MUCL39482 | cds-NP_010056.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:51707-53362:+ | gene-YDL225W_MUCL42920 | rna-NM_001180285.1_MUCL42920 | cds-NP_010056.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:52368-54023:+ | gene-YDL225W_NCIM3186 | rna-NM_001180285.1_NCIM3186 | cds-NP_010056.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:35615-37270:+ | gene-YDL225W_NCYC1407 | rna-NM_001180285.1_NCYC1407 | cds-NP_010056.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:42651-44306:+ | gene-YDL225W_PE2H3 | rna-NM_001180285.1_PE2H3 | cds-NP_010056.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:42661-44316:+ | gene-YDL225W_PE2H4 | rna-NM_001180285.1_PE2H4 | cds-NP_010056.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:52445-54100:+ | gene-YDL225W_S288C | rna-NM_001180285.1_S288C | cds-NP_010056.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000094.1:6844-8499:+ | gene-YDL225W_SA1 | rna-NM_001180285.1_SA1 | cds-NP_010056.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:52466-54121:+ | gene-YDL225W_ThermosaccDry | rna-NM_001180285.1_ThermosaccDry | cds-NP_010056.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:52638-54293:+ | gene-YDL225W_VR1 | rna-NM_001180285.1_VR1 | cds-NP_010056.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:51632-53287:+ | gene-YDL225W_ZTW1 | rna-NM_001180285.1_ZTW1 | cds-NP_010056.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:55047-56702:+ | gene-YDL225W_Sparadoxus | rna-NM_001180285.1_Sparadoxus | cds-NP_010056.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |