SHQ1 (YIL104C)


Gene profile

Gene name: SHQ1
Reference locus (S288C): YIL104C
Gene biotype: protein_coding

Description: Chaperone protein; required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing; functions as an RNA mimic; forms a complex with Naf1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; homology with known Hsp90p cochaperones; relocalizes to the cytosol in response to hypoxia; Belongs to the SHQ1 family

Top 10 interactors (score): NHP2 (0.999); CBF5 (0.999); NOP10 (0.998); GAR1 (0.994); NOP58 (0.956); NAF1 (0.937); RVB1 (0.924); NOP56 (0.923); RVB2 (0.91); PUS4 (0.894); SNU13 (0.891); PIH1 (0.844); HSP82 (0.836); HSC82 (0.818); UTP25 (0.745); TAH1 (0.745); RSA1 (0.678); CBC2 (0.645); DBP8 (0.625); UTP9 (0.609)

Homologues (species, bitscore): SHQ1 (Homo sapiens, 175.3); Shq1 (Mus musculus, 179.5); shq1 (Danio rerio, 178.7); shq1 (Xenopus tropicalis, 183.0); CG10055 (Drosophila melanogaster, 52.0); Y48A5A.1 (Caenorhabditis elegans, 93.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:171448-172971:- gene-YIL104C_AKU4011 rna-NM_001179452.3_AKU4011 cds-NP_012162.3_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:34393-35916:- gene-YIL104C_BG1 rna-NM_001179452.3_BG1 cds-NP_012162.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:176084-177607:- gene-YIL104C_Bruggeman rna-NM_001179452.3_Bruggeman cds-NP_012162.3_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:168135-169658:- gene-YIL104C_CAT1 rna-NM_001179452.3_CAT1 cds-NP_012162.3_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:171704-173227:- gene-YIL104C_CBS1585 rna-NM_001179452.3_CBS1585 cds-NP_012162.3_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:162631-164154:- gene-YIL104C_CBS436 rna-NM_001179452.3_CBS436 cds-NP_012162.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:169084-170607:- gene-YIL104C_CBS6412 rna-NM_001179452.3_CBS6412 cds-NP_012162.3_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:162737-164260:- gene-YIL104C_CBS6413 rna-NM_001179452.3_CBS6413 cds-NP_012162.3_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:161695-163218:- gene-YIL104C_CENPK1137D rna-NM_001179452.3_CENPK1137D cds-NP_012162.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:156671-158194:- gene-YIL104C_EthanolRed rna-NM_001179452.3_EthanolRed cds-NP_012162.3_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:172666-174189:- gene-YIL104C_FaliES1 rna-NM_001179452.3_FaliES1 cds-NP_012162.3_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000025.1:54344-55867:+ gene-YIL104C_JAY291 rna-NM_001179452.3_JAY291 cds-NP_012162.3_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:172920-174443:- gene-YIL104C_MUCL30387 rna-NM_001179452.3_MUCL30387 cds-NP_012162.3_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:171662-173185:- gene-YIL104C_MUCL30388 rna-NM_001179452.3_MUCL30388 cds-NP_012162.3_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:172550-174073:- gene-YIL104C_MUCL39482 rna-NM_001179452.3_MUCL39482 cds-NP_012162.3_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:175804-177327:- gene-YIL104C_MUCL42920 rna-NM_001179452.3_MUCL42920 cds-NP_012162.3_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:169982-171505:- gene-YIL104C_NCIM3186 rna-NM_001179452.3_NCIM3186 cds-NP_012162.3_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:176593-178116:- gene-YIL104C_NCYC1407 rna-NM_001179452.3_NCYC1407 cds-NP_012162.3_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:171092-172615:- gene-YIL104C_PE2H3 rna-NM_001179452.3_PE2H3 cds-NP_012162.3_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:165127-166650:- gene-YIL104C_PE2H4 rna-NM_001179452.3_PE2H4 cds-NP_012162.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:169982-171505:- gene-YIL104C_S288C rna-NM_001179452.3_S288C cds-NP_012162.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000058.1:11874-13397:+ gene-YIL104C_SA1 rna-NM_001179452.3_SA1 cds-NP_012162.3_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:171335-172858:- gene-YIL104C_ThermosaccDry rna-NM_001179452.3_ThermosaccDry cds-NP_012162.3_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:168239-169762:- gene-YIL104C_VR1 rna-NM_001179452.3_VR1 cds-NP_012162.3_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:146268-147791:- gene-YIL104C_ZTW1 rna-NM_001179452.3_ZTW1 cds-NP_012162.3_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:164096-165619:- gene-YIL104C_Sparadoxus rna-NM_001179452.3_Sparadoxus cds-NP_012162.3_Sparadoxus 88.9 99.8 Verified 1 1 1 False True False False False

Additional files