Gene name: SHP1
Reference locus (S288C): YBL058W
Gene biotype: protein_coding
Description: UBX domain-containing substrate adaptor for Cdc48p; ubiquitin regulatory X domain-containing protein that acts as a substrate recruiting cofactor for Cdc48p; positively regulates Glc7p PPase activity to promote growth and mitotic progression in complex with Cdc48p; ubiquitinated protein interactor involved in ER-associated degradation (ERAD); regulated by nuclear Ub-dependent degradation (INMAD pathway) independent of the Asi and Doa10 complexes; homolog of human p47 (NSFL1C)
Top 10 interactors (score): CDC48 (0.999); DOA1 (0.987); UBX7 (0.986); UBX2 (0.985); AFG2 (0.984); UBX4 (0.976); YPI1 (0.96); SDS22 (0.96); UBX5 (0.958); UFD1 (0.944); GLC7 (0.939); NPL4 (0.932); RPT2 (0.92); PPQ1 (0.915); UFD2 (0.91); HSP104 (0.903); FES1 (0.901); MBF1 (0.896); CPR6 (0.896); HSP78 (0.896)
Homologues (species, bitscore): NSFL1C (Homo sapiens, 139.0); Nsfl1c (Mus musculus, 134.4); nsfl1c (Danio rerio, 138.3); ubxn2a (Xenopus tropicalis, 81.6); p47 (Drosophila melanogaster, 114.4); ubxn-2 (Caenorhabditis elegans, 83.2); PUX4 (Arabidopsis thaliana, 114.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:105018-106292:+ | gene-YBL058W_AKU4011 | rna-NM_001178298.1_AKU4011 | cds-NP_009495.1_AKU4011 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:95874-97145:+ | gene-YBL058W_BG1 | rna-NM_001178298.1_BG1 | cds-NP_009495.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:105632-106906:+ | gene-YBL058W_Bruggeman | rna-NM_001178298.1_Bruggeman | cds-NP_009495.1_Bruggeman | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:108270-109544:+ | gene-YBL058W_CAT1 | rna-NM_001178298.1_CAT1 | cds-NP_009495.1_CAT1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:97585-98859:+ | gene-YBL058W_CBS1585 | rna-NM_001178298.1_CBS1585 | cds-NP_009495.1_CBS1585 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:106091-107365:+ | gene-YBL058W_CBS436 | rna-NM_001178298.1_CBS436 | cds-NP_009495.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:96091-97365:+ | gene-YBL058W_CBS6412 | rna-NM_001178298.1_CBS6412 | cds-NP_009495.1_CBS6412 | 98.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:103163-104437:+ | gene-YBL058W_CBS6413 | rna-NM_001178298.1_CBS6413 | cds-NP_009495.1_CBS6413 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:105195-106469:+ | gene-YBL058W_CENPK1137D | rna-NM_001178298.1_CENPK1137D | cds-NP_009495.1_CENPK1137D | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:119017-120291:+ | gene-YBL058W_EthanolRed | rna-NM_001178298.1_EthanolRed | cds-NP_009495.1_EthanolRed | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:119870-121144:+ | gene-YBL058W_FaliES1 | rna-NM_001178298.1_FaliES1 | cds-NP_009495.1_FaliES1 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000072.1:22488-23759:+ | gene-YBL058W_JAY291 | rna-NM_001178298.1_JAY291 | cds-NP_009495.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:105006-106280:+ | gene-YBL058W_MUCL30387 | rna-NM_001178298.1_MUCL30387 | cds-NP_009495.1_MUCL30387 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:106285-107559:+ | gene-YBL058W_MUCL30388 | rna-NM_001178298.1_MUCL30388 | cds-NP_009495.1_MUCL30388 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:97766-99040:+ | gene-YBL058W_MUCL39482 | rna-NM_001178298.1_MUCL39482 | cds-NP_009495.1_MUCL39482 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:104599-105873:+ | gene-YBL058W_MUCL42920 | rna-NM_001178298.1_MUCL42920 | cds-NP_009495.1_MUCL42920 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:111234-112505:+ | gene-YBL058W_NCIM3186 | rna-NM_001178298.1_NCIM3186 | cds-NP_009495.1_NCIM3186 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:98908-100182:+ | gene-YBL058W_NCYC1407 | rna-NM_001178298.1_NCYC1407 | cds-NP_009495.1_NCYC1407 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:105164-106435:+ | gene-YBL058W_PE2H3 | rna-NM_001178298.1_PE2H3 | cds-NP_009495.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:102808-104079:+ | gene-YBL058W_PE2H4 | rna-NM_001178298.1_PE2H4 | cds-NP_009495.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:111437-112708:+ | gene-YBL058W_S288C | rna-NM_001178298.1_S288C | cds-NP_009495.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:95543-96814:+ | gene-YBL058W_SA1 | rna-NM_001178298.1_SA1 | cds-NP_009495.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:119831-121105:+ | gene-YBL058W_ThermosaccDry | rna-NM_001178298.1_ThermosaccDry | cds-NP_009495.1_ThermosaccDry | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:101998-103269:+ | gene-YBL058W_VR1 | rna-NM_001178298.1_VR1 | cds-NP_009495.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:96547-97821:+ | gene-YBL058W_ZTW1 | rna-NM_001178298.1_ZTW1 | cds-NP_009495.1_ZTW1 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:131206-132486:+ | gene-YBL058W_Sparadoxus | rna-NM_001178298.1_Sparadoxus | cds-NP_009495.1_Sparadoxus | 87.0 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |