Gene name: SHO1
Reference locus (S288C): YER118C
Gene biotype: protein_coding
Description: High osmolarity signaling protein SHO1; Transmembrane osmosensor for filamentous growth and HOG pathways; involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol (HOG) response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p
Top 10 interactors (score): PBS2 (0.999); MSB2 (0.999); STE11 (0.999); HOG1 (0.998); CDC42 (0.997); STE50 (0.996); STE20 (0.994); SSK1 (0.992); OPY2 (0.982); SLN1 (0.981); HKR1 (0.977); SSK2 (0.977); YPD1 (0.967); SSK22 (0.964); CDC24 (0.958); HOF1 (0.955); FUS1 (0.931); CYK3 (0.929); AHK1 (0.913); KSS1 (0.895)
Homologues (species, bitscore): NCK1 (Homo sapiens, 51.6); Nck1 (Mus musculus, 51.6); nck1b (Danio rerio, 55.5); nck1 (Xenopus tropicalis, 51.6); src-2 (Caenorhabditis elegans, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:391829-392932:- | gene-YER118C_AKU4011 | rna-NM_001179008.1_AKU4011 | cds-NP_011043.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:32688-33791:+ | gene-YER118C_BG1 | rna-NM_001179008.1_BG1 | cds-NP_011043.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:402300-403403:- | gene-YER118C_Bruggeman | rna-NM_001179008.1_Bruggeman | cds-NP_011043.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:397541-398644:- | gene-YER118C_CAT1 | rna-NM_001179008.1_CAT1 | cds-NP_011043.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:391224-392327:- | gene-YER118C_CBS1585 | rna-NM_001179008.1_CBS1585 | cds-NP_011043.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:393930-395033:- | gene-YER118C_CBS436 | rna-NM_001179008.1_CBS436 | cds-NP_011043.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:390302-391405:- | gene-YER118C_CBS6412 | rna-NM_001179008.1_CBS6412 | cds-NP_011043.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:397146-398249:- | gene-YER118C_CBS6413 | rna-NM_001179008.1_CBS6413 | cds-NP_011043.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:395689-396792:- | gene-YER118C_CENPK1137D | rna-NM_001179008.1_CENPK1137D | cds-NP_011043.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:391678-392781:- | gene-YER118C_EthanolRed | rna-NM_001179008.1_EthanolRed | cds-NP_011043.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:392159-393262:- | gene-YER118C_FaliES1 | rna-NM_001179008.1_FaliES1 | cds-NP_011043.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000028.1:378-1481:- | gene-YER118C_JAY291 | rna-NM_001179008.1_JAY291 | cds-NP_011043.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:399248-400351:- | gene-YER118C_MUCL30387 | rna-NM_001179008.1_MUCL30387 | cds-NP_011043.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:394194-395297:- | gene-YER118C_MUCL30388 | rna-NM_001179008.1_MUCL30388 | cds-NP_011043.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:390249-391352:- | gene-YER118C_MUCL39482 | rna-NM_001179008.1_MUCL39482 | cds-NP_011043.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:398740-399843:- | gene-YER118C_MUCL42920 | rna-NM_001179008.1_MUCL42920 | cds-NP_011043.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:397951-399054:- | gene-YER118C_NCIM3186 | rna-NM_001179008.1_NCIM3186 | cds-NP_011043.1_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:395782-396885:- | gene-YER118C_NCYC1407 | rna-NM_001179008.1_NCYC1407 | cds-NP_011043.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:406327-407430:- | gene-YER118C_PE2H3 | rna-NM_001179008.1_PE2H3 | cds-NP_011043.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:396268-397371:- | gene-YER118C_PE2H4 | rna-NM_001179008.1_PE2H4 | cds-NP_011043.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:397952-399055:- | gene-YER118C_S288C | rna-NM_001179008.1_S288C | cds-NP_011043.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000023.1:107559-108662:- | gene-YER118C_SA1 | rna-NM_001179008.1_SA1 | cds-NP_011043.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:392957-394060:- | gene-YER118C_ThermosaccDry | rna-NM_001179008.1_ThermosaccDry | cds-NP_011043.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:394011-395114:- | gene-YER118C_VR1 | rna-NM_001179008.1_VR1 | cds-NP_011043.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:390066-391169:- | gene-YER118C_ZTW1 | rna-NM_001179008.1_ZTW1 | cds-NP_011043.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:393999-395102:- | gene-YER118C_Sparadoxus | rna-NM_001179008.1_Sparadoxus | cds-NP_011043.1_Sparadoxus | 91.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |