Gene name: SHM1
Reference locus (S288C): YBR263W
Gene biotype: protein_coding
Description: Mitochondrial serine hydroxymethyltransferase; converts serine to glycine plus 5,10 methylenetetrahydrofolate; involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis; reverse reaction generates serine; Belongs to the SHMT family
Top 10 interactors (score): GCV1 (0.998); ADE3 (0.996); MIS1 (0.993); GCV2 (0.986); RMA1 (0.985); DFR1 (0.983); ADE17 (0.982); SER2 (0.982); MET12 (0.982); ADE16 (0.982); MTD1 (0.981); MET7 (0.98); MET13 (0.977); GLY1 (0.975); TRP5 (0.975); GCV3 (0.974); ADE8 (0.974); CDC21 (0.974); HEM1 (0.964); AGX1 (0.959)
Homologues (species, bitscore): SHMT2 (Homo sapiens, 527.3); Shmt1 (Mus musculus, 521.2); shmt2 (Danio rerio, 533.1); shmt1 (Xenopus tropicalis, 533.1); CG3011 (Drosophila melanogaster, 512.7); mel-32 (Caenorhabditis elegans, 544.3); SHM1 (Arabidopsis thaliana, 560.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:720546-722018:+ | gene-YBR263W_AKU4011 | rna-NM_001178611.3_AKU4011 | cds-NP_009822.4_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:91571-93043:+ | gene-YBR263W_BG1 | rna-NM_001178611.3_BG1 | cds-NP_009822.4_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:721710-723182:+ | gene-YBR263W_Bruggeman | rna-NM_001178611.3_Bruggeman | cds-NP_009822.4_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:725437-726909:+ | gene-YBR263W_CAT1 | rna-NM_001178611.3_CAT1 | cds-NP_009822.4_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:712112-713584:+ | gene-YBR263W_CBS1585 | rna-NM_001178611.3_CBS1585 | cds-NP_009822.4_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:718558-720030:+ | gene-YBR263W_CBS436 | rna-NM_001178611.3_CBS436 | cds-NP_009822.4_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:806727-808199:+ | gene-YBR263W_CBS6412 | rna-NM_001178611.3_CBS6412 | cds-NP_009822.4_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:718160-719632:+ | gene-YBR263W_CBS6413 | rna-NM_001178611.3_CBS6413 | cds-NP_009822.4_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:730172-731644:+ | gene-YBR263W_CENPK1137D | rna-NM_001178611.3_CENPK1137D | cds-NP_009822.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:843581-845053:+ | gene-YBR263W_EthanolRed | rna-NM_001178611.3_EthanolRed | cds-NP_009822.4_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:736928-738400:+ | gene-YBR263W_FaliES1 | rna-NM_001178611.3_FaliES1 | cds-NP_009822.4_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:65655-67127:- | gene-YBR263W_JAY291 | rna-NM_001178611.3_JAY291 | cds-NP_009822.4_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:723753-725225:+ | gene-YBR263W_MUCL30387 | rna-NM_001178611.3_MUCL30387 | cds-NP_009822.4_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:740836-742308:+ | gene-YBR263W_MUCL30388 | rna-NM_001178611.3_MUCL30388 | cds-NP_009822.4_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:710419-711891:+ | gene-YBR263W_MUCL39482 | rna-NM_001178611.3_MUCL39482 | cds-NP_009822.4_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:720292-721764:+ | gene-YBR263W_MUCL42920 | rna-NM_001178611.3_MUCL42920 | cds-NP_009822.4_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:736061-737533:+ | gene-YBR263W_NCIM3186 | rna-NM_001178611.3_NCIM3186 | cds-NP_009822.4_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:712308-713780:+ | gene-YBR263W_NCYC1407 | rna-NM_001178611.3_NCYC1407 | cds-NP_009822.4_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:735439-736911:+ | gene-YBR263W_PE2H3 | rna-NM_001178611.3_PE2H3 | cds-NP_009822.4_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:733115-734587:+ | gene-YBR263W_PE2H4 | rna-NM_001178611.3_PE2H4 | cds-NP_009822.4_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:736264-737736:+ | gene-YBR263W_S288C | rna-NM_001178611.3_S288C | cds-NP_009822.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:91390-92862:+ | gene-YBR263W_SA1 | rna-NM_001178611.3_SA1 | cds-NP_009822.4_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:735920-737392:+ | gene-YBR263W_ThermosaccDry | rna-NM_001178611.3_ThermosaccDry | cds-NP_009822.4_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:716137-717609:+ | gene-YBR263W_VR1 | rna-NM_001178611.3_VR1 | cds-NP_009822.4_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:708766-710238:+ | gene-YBR263W_ZTW1 | rna-NM_001178611.3_ZTW1 | cds-NP_009822.4_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:752671-754143:+ | gene-YBR263W_Sparadoxus | rna-NM_001178611.3_Sparadoxus | cds-NP_009822.4_Sparadoxus | 91.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |