Gene name: SHB17
Reference locus (S288C): YKR043C
Gene biotype: protein_coding
Description: Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus
Top 10 interactors (score): TAL1 (0.844); TKL1 (0.781); DAS2 (0.766); TPI1 (0.764); RPE1 (0.762); SEC4 (0.748); RKI1 (0.745); PGK1 (0.739); ZWF1 (0.731); CDC21 (0.69); FBA1 (0.686); PGI1 (0.661); DAK1 (0.579); THI11 (0.571); MTM1 (0.568); DAK2 (0.562); RPP1B (0.539); PFK1 (0.522); PDC1 (0.485); MDH1 (0.482)
Homologues (species, bitscore): c12orf5 (Xenopus tropicalis, 52.8); AT3G50520 (Arabidopsis thaliana, 56.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:506180-506995:- | gene-YKR043C_AKU4011 | rna-NM_001179833.1_AKU4011 | cds-NP_012969.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:136533-137348:+ | gene-YKR043C_BG1 | rna-NM_001179833.1_BG1 | cds-NP_012969.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:528361-529176:- | gene-YKR043C_Bruggeman | rna-NM_001179833.1_Bruggeman | cds-NP_012969.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:524795-525610:- | gene-YKR043C_CAT1 | rna-NM_001179833.1_CAT1 | cds-NP_012969.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:518924-519739:- | gene-YKR043C_CBS1585 | rna-NM_001179833.1_CBS1585 | cds-NP_012969.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:517764-518579:- | gene-YKR043C_CBS436 | rna-NM_001179833.1_CBS436 | cds-NP_012969.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:503100-503915:- | gene-YKR043C_CBS6412 | rna-NM_001179833.1_CBS6412 | cds-NP_012969.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:518740-519555:- | gene-YKR043C_CBS6413 | rna-NM_001179833.1_CBS6413 | cds-NP_012969.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:520557-521372:- | gene-YKR043C_CENPK1137D | rna-NM_001179833.1_CENPK1137D | cds-NP_012969.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:516516-517331:- | gene-YKR043C_EthanolRed | rna-NM_001179833.1_EthanolRed | cds-NP_012969.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:519640-520455:- | gene-YKR043C_FaliES1 | rna-NM_001179833.1_FaliES1 | cds-NP_012969.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000077.1:33351-34166:+ | gene-YKR043C_JAY291 | rna-NM_001179833.1_JAY291 | cds-NP_012969.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:528760-529575:- | gene-YKR043C_MUCL30387 | rna-NM_001179833.1_MUCL30387 | cds-NP_012969.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:523123-523938:- | gene-YKR043C_MUCL30388 | rna-NM_001179833.1_MUCL30388 | cds-NP_012969.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:518250-519065:- | gene-YKR043C_MUCL39482 | rna-NM_001179833.1_MUCL39482 | cds-NP_012969.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:524271-525086:- | gene-YKR043C_MUCL42920 | rna-NM_001179833.1_MUCL42920 | cds-NP_012969.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:520886-521701:- | gene-YKR043C_NCIM3186 | rna-NM_001179833.1_NCIM3186 | cds-NP_012969.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:518462-519277:- | gene-YKR043C_NCYC1407 | rna-NM_001179833.1_NCYC1407 | cds-NP_012969.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:543779-544594:- | gene-YKR043C_PE2H3 | rna-NM_001179833.1_PE2H3 | cds-NP_012969.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:528176-528991:- | gene-YKR043C_PE2H4 | rna-NM_001179833.1_PE2H4 | cds-NP_012969.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:520897-521712:- | gene-YKR043C_S288C | rna-NM_001179833.1_S288C | cds-NP_012969.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000093.1:3894-4709:- | gene-YKR043C_SA1 | rna-NM_001179833.1_SA1 | cds-NP_012969.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:518893-519708:- | gene-YKR043C_ThermosaccDry | rna-NM_001179833.1_ThermosaccDry | cds-NP_012969.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:518470-519285:- | gene-YKR043C_VR1 | rna-NM_001179833.1_VR1 | cds-NP_012969.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:516895-517710:- | gene-YKR043C_ZTW1 | rna-NM_001179833.1_ZTW1 | cds-NP_012969.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:542365-543180:- | gene-YKR043C_Sparadoxus | rna-NM_001179833.1_Sparadoxus | cds-NP_012969.1_Sparadoxus | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |