SGV1 (YPR161C)


Gene profile

Gene name: SGV1
Reference locus (S288C): YPR161C
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase BUR1; Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins

Top 10 interactors (score): CTK2 (0.999); BUR2 (0.999); RPO21 (0.999); SPT5 (0.999); SPT4 (0.985); FCP1 (0.973); SET2 (0.966); CTK1 (0.963); SPT16 (0.93); SER2 (0.928); SSU72 (0.92); SPT6 (0.918); DST1 (0.914); CCL1 (0.898); RPB3 (0.891); CTR9 (0.887); SET1 (0.874); THR4 (0.863); CTK3 (0.861); CDC73 (0.861)

Homologues (species, bitscore): CDK11B (Homo sapiens, 237.7); Cdk11b (Mus musculus, 238.8); cdk13 (Danio rerio, 245.4); cdk9 (Xenopus tropicalis, 236.1); Cdk9 (Drosophila melanogaster, 249.2); cdk-9 (Caenorhabditis elegans, 244.2); AT1G67580 (Arabidopsis thaliana, 251.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:818726-820699:- gene-YPR161C_AKU4011 rna-NM_001184258.1_AKU4011 cds-NP_015487.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:77017-78990:+ gene-YPR161C_BG1 rna-NM_001184258.1_BG1 cds-NP_015487.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:898918-900891:- gene-YPR161C_Bruggeman rna-NM_001184258.1_Bruggeman cds-NP_015487.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:941524-943497:- gene-YPR161C_CAT1 rna-NM_001184258.1_CAT1 cds-NP_015487.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:823526-825499:- gene-YPR161C_CBS1585 rna-NM_001184258.1_CBS1585 cds-NP_015487.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:837081-839054:- gene-YPR161C_CBS436 rna-NM_001184258.1_CBS436 cds-NP_015487.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:825390-827363:- gene-YPR161C_CBS6412 rna-NM_001184258.1_CBS6412 cds-NP_015487.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:820456-822429:- gene-YPR161C_CBS6413 rna-NM_001184258.1_CBS6413 cds-NP_015487.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:864460-866433:- gene-YPR161C_CENPK1137D rna-NM_001184258.1_CENPK1137D cds-NP_015487.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1140360-1142333:- gene-YPR161C_EthanolRed rna-NM_001184258.1_EthanolRed cds-NP_015487.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:820066-822039:- gene-YPR161C_FaliES1 rna-NM_001184258.1_FaliES1 cds-NP_015487.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000081.1:7856-9830:- gene-YPR161C_JAY291 rna-NM_001184258.1_JAY291 cds-NP_015487.1_JAY291 99.7 100.0 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:867003-868976:- gene-YPR161C_MUCL30387 rna-NM_001184258.1_MUCL30387 cds-NP_015487.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:839582-841555:- gene-YPR161C_MUCL30388 rna-NM_001184258.1_MUCL30388 cds-NP_015487.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:815728-817701:- gene-YPR161C_MUCL39482 rna-NM_001184258.1_MUCL39482 cds-NP_015487.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:879390-881363:- gene-YPR161C_MUCL42920 rna-NM_001184258.1_MUCL42920 cds-NP_015487.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:864432-866405:- gene-YPR161C_NCIM3186 rna-NM_001184258.1_NCIM3186 cds-NP_015487.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:824089-826062:- gene-YPR161C_NCYC1407 rna-NM_001184258.1_NCYC1407 cds-NP_015487.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:836381-838354:- gene-YPR161C_PE2H3 rna-NM_001184258.1_PE2H3 cds-NP_015487.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:836029-838002:- gene-YPR161C_PE2H4 rna-NM_001184258.1_PE2H4 cds-NP_015487.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:864449-866422:- gene-YPR161C_S288C rna-NM_001184258.1_S288C cds-NP_015487.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000060.1:59737-61710:+ gene-YPR161C_SA1 rna-NM_001184258.1_SA1 cds-NP_015487.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:819754-821727:- gene-YPR161C_ThermosaccDry rna-NM_001184258.1_ThermosaccDry cds-NP_015487.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:848036-850009:- gene-YPR161C_VR1 rna-NM_001184258.1_VR1 cds-NP_015487.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:822876-824849:- gene-YPR161C_ZTW1 rna-NM_001184258.1_ZTW1 cds-NP_015487.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:824940-826913:- gene-YPR161C_Sparadoxus rna-NM_001184258.1_Sparadoxus cds-NP_015487.1_Sparadoxus 90.0 99.9 Verified 1 1 1 False True False False False

Additional files