Gene name: SGT1
Reference locus (S288C): YOR057W
Gene biotype: protein_coding
Description: Cochaperone protein; regulates activity of adenylyl cyclase Cyr1p; involved in kinetochore complex assembly; associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex; acts as a linker between Skp1p and HSP90 complexes; protein abundance increases in response to DNA replication stress; Belongs to the SGT1 family
Top 10 interactors (score): HSC82 (0.999); SKP1 (0.999); HSP82 (0.999); CYR1 (0.99); CDC37 (0.976); STI1 (0.954); AHA1 (0.948); SBA1 (0.913); CTF13 (0.901); STE4 (0.881); TAH1 (0.836); URA3 (0.795); ERG12 (0.766); CNS1 (0.765); PML39 (0.731); CEP3 (0.716); HCH1 (0.696); URA5 (0.693); GPR1 (0.69); MES1 (0.682)
Homologues (species, bitscore): SUGT1 (Homo sapiens, 105.5); Sugt1 (Mus musculus, 105.9); sgut1 (Danio rerio, 102.4); sugt1 (Xenopus tropicalis, 121.7); Sgt1 (Drosophila melanogaster, 89.4); D1054.3 (Caenorhabditis elegans, 83.6); SGT1A (Arabidopsis thaliana, 111.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:416522-417709:+ | gene-YOR057W_AKU4011 | rna-NM_001183476.1_AKU4011 | cds-NP_014700.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000088.1:15052-16049:- | gene-YOR057W_BG1 | rna-NM_001183476.1_BG1 | cds-NP_014700.1_BG1 | 83.4 | 84.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:419235-420422:+ | gene-YOR057W_Bruggeman | rna-NM_001183476.1_Bruggeman | cds-NP_014700.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:417419-418606:+ | gene-YOR057W_CAT1 | rna-NM_001183476.1_CAT1 | cds-NP_014700.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:411208-412395:+ | gene-YOR057W_CBS1585 | rna-NM_001183476.1_CBS1585 | cds-NP_014700.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:415513-416700:+ | gene-YOR057W_CBS436 | rna-NM_001183476.1_CBS436 | cds-NP_014700.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:410535-411722:+ | gene-YOR057W_CBS6412 | rna-NM_001183476.1_CBS6412 | cds-NP_014700.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:417819-419006:+ | gene-YOR057W_CBS6413 | rna-NM_001183476.1_CBS6413 | cds-NP_014700.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:432170-433357:+ | gene-YOR057W_CENPK1137D | rna-NM_001183476.1_CENPK1137D | cds-NP_014700.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:413239-414426:+ | gene-YOR057W_EthanolRed | rna-NM_001183476.1_EthanolRed | cds-NP_014700.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:416575-417762:+ | gene-YOR057W_FaliES1 | rna-NM_001183476.1_FaliES1 | cds-NP_014700.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000195.1:4966-6153:- | gene-YOR057W_JAY291 | rna-NM_001183476.1_JAY291 | cds-NP_014700.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:424015-425202:+ | gene-YOR057W_MUCL30387 | rna-NM_001183476.1_MUCL30387 | cds-NP_014700.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:428425-429612:+ | gene-YOR057W_MUCL30388 | rna-NM_001183476.1_MUCL30388 | cds-NP_014700.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:418693-419880:+ | gene-YOR057W_MUCL39482 | rna-NM_001183476.1_MUCL39482 | cds-NP_014700.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:433502-434689:+ | gene-YOR057W_MUCL42920 | rna-NM_001183476.1_MUCL42920 | cds-NP_014700.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:432075-433262:+ | gene-YOR057W_NCIM3186 | rna-NM_001183476.1_NCIM3186 | cds-NP_014700.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:425362-426549:+ | gene-YOR057W_NCYC1407 | rna-NM_001183476.1_NCYC1407 | cds-NP_014700.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:424217-425404:+ | gene-YOR057W_PE2H3 | rna-NM_001183476.1_PE2H3 | cds-NP_014700.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:434598-435785:+ | gene-YOR057W_PE2H4 | rna-NM_001183476.1_PE2H4 | cds-NP_014700.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:432186-433373:+ | gene-YOR057W_S288C | rna-NM_001183476.1_S288C | cds-NP_014700.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:400112-401299:+ | gene-YOR057W_SA1 | rna-NM_001183476.1_SA1 | cds-NP_014700.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:415116-416303:+ | gene-YOR057W_ThermosaccDry | rna-NM_001183476.1_ThermosaccDry | cds-NP_014700.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:416532-417719:+ | gene-YOR057W_VR1 | rna-NM_001183476.1_VR1 | cds-NP_014700.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:149728-150915:+ | gene-YOR057W_ZTW1 | rna-NM_001183476.1_ZTW1 | cds-NP_014700.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:422617-423804:+ | gene-YOR057W_Sparadoxus | rna-NM_001183476.1_Sparadoxus | cds-NP_014700.1_Sparadoxus | 86.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |