Gene name: SGF73
Reference locus (S288C): YGL066W
Gene biotype: protein_coding
Description: SAGA-associated factor 73; Subunit of DUBm module of SAGA and SLIK; has roles in anchoring deubiquitination module (DUBm) into SAGA and SLIK complexes, maintaining organization and ubiquitin-binding conformation of Ubp8p, thereby contributing to overall DUBm activity; involved in preinitiation complex assembly at promoters; relocalizes to cytosol under hypoxia; human homolog ATXN7 implicated in spinocerebellar ataxia, and can complement yeast null mutant
Top 10 interactors (score): TAF10 (0.999); ADA2 (0.999); TRA1 (0.999); SPT7 (0.999); HFI1 (0.999); NGG1 (0.999); TAF5 (0.999); TAF6 (0.999); SGF29 (0.999); TAF9 (0.999); SPT3 (0.999); SGF11 (0.999); TAF12 (0.999); SPT20 (0.999); UBP8 (0.999); SUS1 (0.999); GCN5 (0.999); SPT8 (0.999); SPT15 (0.973); CHD1 (0.961)
Homologues (species, bitscore): ATXN7L1 (Homo sapiens, 59.3); Atxn7l1 (Mus musculus, 59.3); ATXN7L1 (Danio rerio, 61.2); atxn7l1 (Xenopus tropicalis, 61.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:380613-382571:+ | gene-YGL066W_AKU4011 | rna-NM_001180931.1_AKU4011 | cds-NP_011449.1_AKU4011 | 98.6 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:22820-24784:- | gene-YGL066W_BG1 | rna-NM_001180931.1_BG1 | cds-NP_011449.1_BG1 | 99.3 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:383092-385050:+ | gene-YGL066W_Bruggeman | rna-NM_001180931.1_Bruggeman | cds-NP_011449.1_Bruggeman | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:380089-382047:+ | gene-YGL066W_CAT1 | rna-NM_001180931.1_CAT1 | cds-NP_011449.1_CAT1 | 98.9 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:384158-386116:+ | gene-YGL066W_CBS1585 | rna-NM_001180931.1_CBS1585 | cds-NP_011449.1_CBS1585 | 98.6 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:378296-380257:+ | gene-YGL066W_CBS436 | rna-NM_001180931.1_CBS436 | cds-NP_011449.1_CBS436 | 99.3 | 99.3 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:368317-370275:+ | gene-YGL066W_CBS6412 | rna-NM_001180931.1_CBS6412 | cds-NP_011449.1_CBS6412 | 98.5 | 99.2 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:378243-380201:+ | gene-YGL066W_CBS6413 | rna-NM_001180931.1_CBS6413 | cds-NP_011449.1_CBS6413 | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:377796-379769:+ | gene-YGL066W_CENPK1137D | rna-NM_001180931.1_CENPK1137D | cds-NP_011449.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:369685-371643:+ | gene-YGL066W_EthanolRed | rna-NM_001180931.1_EthanolRed | cds-NP_011449.1_EthanolRed | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:372246-374204:+ | gene-YGL066W_FaliES1 | rna-NM_001180931.1_FaliES1 | cds-NP_011449.1_FaliES1 | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000369.1:57953-59914:+ | gene-YGL066W_JAY291 | rna-NM_001180931.1_JAY291 | cds-NP_011449.1_JAY291 | 99.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:380288-382246:+ | gene-YGL066W_MUCL30387 | rna-NM_001180931.1_MUCL30387 | cds-NP_011449.1_MUCL30387 | 98.8 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:383056-385293:+ | gene-YGL066W_MUCL30388 | rna-NM_001180931.1_MUCL30388 | cds-NP_011449.1_MUCL30388 | 86.6 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:380466-382424:+ | gene-YGL066W_MUCL39482 | rna-NM_001180931.1_MUCL39482 | cds-NP_011449.1_MUCL39482 | 98.6 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:191681-193642:- | gene-YGL066W_MUCL42920 | rna-NM_001180931.1_MUCL42920 | cds-NP_011449.1_MUCL42920 | 99.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:377609-379582:+ | gene-YGL066W_NCIM3186 | rna-NM_001180931.1_NCIM3186 | cds-NP_011449.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:371999-373957:+ | gene-YGL066W_NCYC1407 | rna-NM_001180931.1_NCYC1407 | cds-NP_011449.1_NCYC1407 | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:373654-375615:+ | gene-YGL066W_PE2H3 | rna-NM_001180931.1_PE2H3 | cds-NP_011449.1_PE2H3 | 99.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:378704-380665:+ | gene-YGL066W_PE2H4 | rna-NM_001180931.1_PE2H4 | cds-NP_011449.1_PE2H4 | 99.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:377609-379582:+ | gene-YGL066W_S288C | rna-NM_001180931.1_S288C | cds-NP_011449.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000096.1:12758-14749:+ | gene-YGL066W_SA1 | rna-NM_001180931.1_SA1 | cds-NP_011449.1_SA1 | 98.3 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:372497-374455:+ | gene-YGL066W_ThermosaccDry | rna-NM_001180931.1_ThermosaccDry | cds-NP_011449.1_ThermosaccDry | 98.6 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:482878-484842:+ | gene-YGL066W_VR1 | rna-NM_001180931.1_VR1 | cds-NP_011449.1_VR1 | 99.4 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:369860-371818:+ | gene-YGL066W_ZTW1 | rna-NM_001180931.1_ZTW1 | cds-NP_011449.1_ZTW1 | 98.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:375470-377443:+ | gene-YGL066W_Sparadoxus | rna-NM_001180931.1_Sparadoxus | cds-NP_011449.1_Sparadoxus | 87.5 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |