Gene name: SFP1
Reference locus (S288C): YLR403W
Gene biotype: protein_coding
Description: Transcription factor SFP1; Regulates transcription of ribosomal protein and biogenesis genes; regulates response to nutrients and stress, G2/M transitions during mitotic cell cycle and DNA-damage response, and modulates cell size; regulated by TORC1 and Mrs6p; sequence of zinc finger, ChIP localization data, and protein-binding microarray (PBM) data, and computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p at others; can form the [ISP+] prion
Top 10 interactors (score): MRS6 (0.975); IFH1 (0.97); SCH9 (0.958); FHL1 (0.929); RAP1 (0.868); STB3 (0.865); MSN2 (0.861); TOR1 (0.851); TOD6 (0.828); MSN4 (0.827); DOT6 (0.82); HSF1 (0.763); HMO1 (0.763); YAP1 (0.762); MOT3 (0.758); MRPL25 (0.749); GCN4 (0.748); SKN7 (0.745); CDC123 (0.743); SWI1 (0.737)
Homologues (species, bitscore): JAZF1 (Homo sapiens, 66.2); Jazf1 (Mus musculus, 66.6); si:ch211-276c2.4 (Danio rerio, 71.6); jazf1 (Xenopus tropicalis, 65.5); CG12054 (Drosophila melanogaster, 62.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:875102-877153:+ | gene-YLR403W_AKU4011 | rna-NM_001182291.1_AKU4011 | cds-NP_013507.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:107245-109296:+ | gene-YLR403W_BG1 | rna-NM_001182291.1_BG1 | cds-NP_013507.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:913407-915458:+ | gene-YLR403W_Bruggeman | rna-NM_001182291.1_Bruggeman | cds-NP_013507.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:908931-910982:+ | gene-YLR403W_CAT1 | rna-NM_001182291.1_CAT1 | cds-NP_013507.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:910698-912749:+ | gene-YLR403W_CBS1585 | rna-NM_001182291.1_CBS1585 | cds-NP_013507.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:894336-896387:+ | gene-YLR403W_CBS436 | rna-NM_001182291.1_CBS436 | cds-NP_013507.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:946739-948790:+ | gene-YLR403W_CBS6412 | rna-NM_001182291.1_CBS6412 | cds-NP_013507.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:910989-913040:+ | gene-YLR403W_CBS6413 | rna-NM_001182291.1_CBS6413 | cds-NP_013507.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:910379-912430:+ | gene-YLR403W_CENPK1137D | rna-NM_001182291.1_CENPK1137D | cds-NP_013507.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:867645-869696:+ | gene-YLR403W_EthanolRed | rna-NM_001182291.1_EthanolRed | cds-NP_013507.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:896955-899006:+ | gene-YLR403W_FaliES1 | rna-NM_001182291.1_FaliES1 | cds-NP_013507.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000434.1:50114-52165:+ | gene-YLR403W_JAY291 | rna-NM_001182291.1_JAY291 | cds-NP_013507.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:912273-914324:+ | gene-YLR403W_MUCL30387 | rna-NM_001182291.1_MUCL30387 | cds-NP_013507.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:918359-920422:+ | gene-YLR403W_MUCL30388 | rna-NM_001182291.1_MUCL30388 | cds-NP_013507.1_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:911918-913969:+ | gene-YLR403W_MUCL39482 | rna-NM_001182291.1_MUCL39482 | cds-NP_013507.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:906573-908624:+ | gene-YLR403W_MUCL42920 | rna-NM_001182291.1_MUCL42920 | cds-NP_013507.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:925542-927593:+ | gene-YLR403W_NCIM3186 | rna-NM_001182291.1_NCIM3186 | cds-NP_013507.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:921098-923149:+ | gene-YLR403W_NCYC1407 | rna-NM_001182291.1_NCYC1407 | cds-NP_013507.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:907495-909546:+ | gene-YLR403W_PE2H3 | rna-NM_001182291.1_PE2H3 | cds-NP_013507.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:907239-909290:+ | gene-YLR403W_PE2H4 | rna-NM_001182291.1_PE2H4 | cds-NP_013507.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:925568-927619:+ | gene-YLR403W_S288C | rna-NM_001182291.1_S288C | cds-NP_013507.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:121070-123121:- | gene-YLR403W_SA1 | rna-NM_001182291.1_SA1 | cds-NP_013507.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:900034-902085:+ | gene-YLR403W_ThermosaccDry | rna-NM_001182291.1_ThermosaccDry | cds-NP_013507.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:912585-914636:+ | gene-YLR403W_VR1 | rna-NM_001182291.1_VR1 | cds-NP_013507.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:236752-238803:+ | gene-YLR403W_ZTW1 | rna-NM_001182291.1_ZTW1 | cds-NP_013507.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:885478-887541:+ | gene-YLR403W_Sparadoxus | rna-NM_001182291.1_Sparadoxus | cds-NP_013507.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |