Gene name: SFL1
Reference locus (S288C): YOR140W
Gene biotype: protein_coding
Description: Flocculation suppression protein; Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; has direct role in INO1 transcriptional memory; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p; premature stop codon (C1430T, Q477-stop) in SK1 background is linked to the aggressively invasive phenotype of SK1 relative to BY4741 (S288C)
Top 10 interactors (score): TEC1 (0.947); FLO11 (0.945); CYC8 (0.923); SSN8 (0.914); TPK2 (0.898); FLO8 (0.896); ROX3 (0.892); TUP1 (0.865); SIN4 (0.851); MSS11 (0.836); STE12 (0.819); NRG1 (0.814); RIM101 (0.783); GCN4 (0.77); CYR1 (0.77); BMH1 (0.752); HDA1 (0.73); FLO10 (0.715); FLO1 (0.711); PHD1 (0.697)
Homologues (species, bitscore): HSF2 (Homo sapiens, 76.3); Hsf2 (Mus musculus, 75.9); LOC792628 (Danio rerio, 82.8); hsf2 (Xenopus tropicalis, 77.8); Hsf (Drosophila melanogaster, 71.2); hsf-1 (Caenorhabditis elegans, 64.7); AT-HSFB2B (Arabidopsis thaliana, 84.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:590433-592733:+ | gene-YOR140W_AKU4011 | rna-NM_001183559.4_AKU4011 | cds-NP_014783.4_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:5876-8176:- | gene-YOR140W_BG1 | rna-NM_001183559.4_BG1 | cds-NP_014783.4_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:574593-576893:+ | gene-YOR140W_Bruggeman | rna-NM_001183559.4_Bruggeman | cds-NP_014783.4_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:574614-576914:+ | gene-YOR140W_CAT1 | rna-NM_001183559.4_CAT1 | cds-NP_014783.4_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:566613-568913:+ | gene-YOR140W_CBS1585 | rna-NM_001183559.4_CBS1585 | cds-NP_014783.4_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:571317-573617:+ | gene-YOR140W_CBS436 | rna-NM_001183559.4_CBS436 | cds-NP_014783.4_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:564100-566400:+ | gene-YOR140W_CBS6412 | rna-NM_001183559.4_CBS6412 | cds-NP_014783.4_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:572894-575194:+ | gene-YOR140W_CBS6413 | rna-NM_001183559.4_CBS6413 | cds-NP_014783.4_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:586732-589032:+ | gene-YOR140W_CENPK1137D | rna-NM_001183559.4_CENPK1137D | cds-NP_014783.4_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:566745-569045:+ | gene-YOR140W_EthanolRed | rna-NM_001183559.4_EthanolRed | cds-NP_014783.4_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:571598-573898:+ | gene-YOR140W_FaliES1 | rna-NM_001183559.4_FaliES1 | cds-NP_014783.4_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000070.1:69652-71952:- | gene-YOR140W_JAY291 | rna-NM_001183559.4_JAY291 | cds-NP_014783.4_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:579150-581450:+ | gene-YOR140W_MUCL30387 | rna-NM_001183559.4_MUCL30387 | cds-NP_014783.4_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:585232-587532:+ | gene-YOR140W_MUCL30388 | rna-NM_001183559.4_MUCL30388 | cds-NP_014783.4_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:574687-576987:+ | gene-YOR140W_MUCL39482 | rna-NM_001183559.4_MUCL39482 | cds-NP_014783.4_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:590285-592585:+ | gene-YOR140W_MUCL42920 | rna-NM_001183559.4_MUCL42920 | cds-NP_014783.4_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:586870-589170:+ | gene-YOR140W_NCIM3186 | rna-NM_001183559.4_NCIM3186 | cds-NP_014783.4_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:580953-583253:+ | gene-YOR140W_NCYC1407 | rna-NM_001183559.4_NCYC1407 | cds-NP_014783.4_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:579459-581759:+ | gene-YOR140W_PE2H3 | rna-NM_001183559.4_PE2H3 | cds-NP_014783.4_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:589836-592136:+ | gene-YOR140W_PE2H4 | rna-NM_001183559.4_PE2H4 | cds-NP_014783.4_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:586981-589281:+ | gene-YOR140W_S288C | rna-NM_001183559.4_S288C | cds-NP_014783.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:9445-11745:+ | gene-YOR140W_SA1 | rna-NM_001183559.4_SA1 | cds-NP_014783.4_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:570781-573081:+ | gene-YOR140W_ThermosaccDry | rna-NM_001183559.4_ThermosaccDry | cds-NP_014783.4_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:634459-636759:+ | gene-YOR140W_VR1 | rna-NM_001183559.4_VR1 | cds-NP_014783.4_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:304231-306530:+ | gene-YOR140W_ZTW1 | rna-NM_001183559.4_ZTW1 | cds-NP_014783.4_ZTW1 | 99.3 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:575630-577936:+ | gene-YOR140W_Sparadoxus | rna-NM_001183559.4_Sparadoxus | cds-NP_014783.4_Sparadoxus | 90.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |